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Organ-Dedicated Molecular Imaging Systems

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Organ-Dedicated Molecular Imaging Systems

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dc.contributor.author González Martínez, Antonio Javier es_ES
dc.contributor.author Sánchez, F. es_ES
dc.contributor.author Benlloch Baviera, Jose María es_ES
dc.date.accessioned 2020-11-04T04:32:27Z
dc.date.available 2020-11-04T04:32:27Z
dc.date.issued 2018-09 es_ES
dc.identifier.issn 2469-7311 es_ES
dc.identifier.uri http://hdl.handle.net/10251/154033
dc.description.abstract [EN] In this review, we will cover both clinical and technical aspects of the advantages and disadvantages of organ specific (dedicated) molecular imaging (MI) systems, namely positron emission tomography (PET) and single photon emission computed tomography, including gamma cameras. This review will start with the introduction to the organ-dedicated MI systems. Thereafter, we will describe the differences and their advantages/disadvantages when compared with the standard large size scanners. We will review time evolution of dedicated systems, from first attempts to current scanners, and the ones that ended in clinical use. We will review later the state of the art of these systems for different organs, namely: breast, brain, heart, and prostate. We will also present the advantages offered by these systems as a function of the special application or field, such as in surgery, therapy assistance and assessment, etc. Their technological evolution will be introduced for each organ-based imager. Some of the advantages of dedicated devices are: higher sensitivity by placing the detectors closer to the organ, improved spatial resolution, better image contrast recovery (by reducing the noise from other organs), and also lower cost. Designing a complete ring-shaped dedicated PET scanner is sometimes difficult and limited angle tomography systems are preferable as they have more flexibility in placing the detectors around the body/organ. Examples of these geometries will be presented for breast, prostate and heart imaging. Recently achievable excellent time of flight capabilities below 300-ps full width at half of the maximum reduce significantly the impact of missing angles on the reconstructed images. es_ES
dc.description.sponsorship This work was supported in part by the European Research Council through the European Union's Horizon 2020 Research and Innovation Program under Grant 695536, in part by the EU through the FP7 Program under Grant 603002, and in part by the Spanish Ministerio de Economia, Industria y Competitividad through PROSPET (DTS15/00152) funded by the Ministerio de Economia y Competitividad under Grant TEC2016-79884-C2-1-R. es_ES
dc.language Inglés es_ES
dc.publisher Institute of Electrical and Electronics Engineers es_ES
dc.relation.ispartof IEEE Transactions on Radiation and Plasma Medical Sciences es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Compact equipment es_ES
dc.subject Nuclear medicine es_ES
dc.subject Organ dedicated positron emission tomography (PET) es_ES
dc.subject Organ specific/dedicated single photon emission computed tomography (SPECT) es_ES
dc.title Organ-Dedicated Molecular Imaging Systems es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1109/TRPMS.2018.2846745 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/603002/EU/Multimodal Imaging of Neurological Disorders/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//TEC2016-79884-C2-1-R/ES/DESARROLLO DEL HARDWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE ESTRES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/695536/EU/Innovative PET scanner for dynamic imaging/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes es_ES
dc.description.bibliographicCitation González Martínez, AJ.; Sánchez, F.; Benlloch Baviera, JM. (2018). Organ-Dedicated Molecular Imaging Systems. IEEE Transactions on Radiation and Plasma Medical Sciences. 2(5):388-403. https://doi.org/10.1109/TRPMS.2018.2846745 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1109/TRPMS.2018.2846745 es_ES
dc.description.upvformatpinicio 388 es_ES
dc.description.upvformatpfin 403 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 2 es_ES
dc.description.issue 5 es_ES
dc.relation.pasarela S\406015 es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES


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