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A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

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A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

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Vendrell-Criado, V.; González-Bello, C.; Miranda Alonso, MÁ.; Jiménez Molero, MC. (2018). A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins. Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy. 199:308-314. https://doi.org/10.1016/j.saa.2018.03.064

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/154805

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Title: A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins
Author: Vendrell-Criado, Victoria González-Bello, Concepción Miranda Alonso, Miguel Ángel Jiménez Molero, María Consuelo
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Binding of the inmunodrepresive agent mycophenolate mofetil (MMP) and its pharmacologically active metabolite mycophenolic acid (MPA) to human serum albumin (HSA) and ¿1-acid glycoprotein (HAAG) has been investigated ...[+]
Subjects: Drug-protein binding , Docking , Fluorescence , Human serum albumin , Human alpha(1)-acid glycoprotein
Copyrigths: Reserva de todos los derechos
Source:
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy. (issn: 1386-1425 )
DOI: 10.1016/j.saa.2018.03.064
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.saa.2018.03.064
Project ID:
info:eu-repo/grantAgreement/MINECO//SAF2016-75638-R/ES/DESARROLLO DE NUEVOS FARMACOS PARA EL TRATAMIENTO DE LAS INFECCIONES BACTERIANAS MULTIRESISTENTES: APROXIMACIONES QUE INCIDEN SOBRE VIABILIDAD, RESISTENCIA Y VIRULENCIA/
info:eu-repo/grantAgreement/Xunta de Galicia//ED431G%2F09/
info:eu-repo/grantAgreement/MINECO//CTQ2013-47872-C2-1-P/ES/METABOLITOS FOTOACTIVOS/
info:eu-repo/grantAgreement/MINECO//CTQ2016-78875-P/ES/CONTROL SUPRAMOLECULAR DE LA FOTORREACTIVIDAD EN MEDIOS MICROHETEROGENOS BASADOS EN AMINOACIDOS: GELES MOLECULARES Y PROTEINAS TRANSPORTADORAS COMO NANORREACTORES/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2017%2F075/ES/Reacciones fotoquímicas de biomoléculas/
Thanks:
Financial support from the Spanish Ministry of Economy and Competiveness (CTQ2013-47872-C2-1-P, CTQ2016-78875-P, SAF2016-75638-R), the Xunta de Galicia (Centro singular de investigacion de Galicia accreditation 2016-2019, ...[+]
Type: Artículo

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