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The effect of salt fusion processing variables on structural, physicochemical and biological properties of poly(glycerol sebacate) scaffolds

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The effect of salt fusion processing variables on structural, physicochemical and biological properties of poly(glycerol sebacate) scaffolds

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dc.contributor.author Vilariño, Guillermo es_ES
dc.contributor.author Muñoz-Santa, A. es_ES
dc.contributor.author Conejero-Garcia, Álvaro es_ES
dc.contributor.author Vallés Lluch, Ana es_ES
dc.date.accessioned 2020-12-17T04:32:48Z
dc.date.available 2020-12-17T04:32:48Z
dc.date.issued 2020-09-21 es_ES
dc.identifier.issn 0091-4037 es_ES
dc.identifier.uri http://hdl.handle.net/10251/157281
dc.description "This is an Accepted Manuscript of an article published by Taylor & Francis in International Journal of Polymeric Materials and Polymeric Biomaterials on SEP 21 2020, available online: https://www.tandfonline.com/doi/full/10.1080/00914037.2019.1636247" es_ES
dc.description.abstract [EN] Poly(glycerol sebacate), PGS, is a biodegradable elastomer recently proposed in the form of scaffolds for cardiac, vascular, cartilage or neural applications. In the present work, several processing variables for the fabrication of PGS scaffolds by the salt fusion method were systematically studied, namely the pre-polymer/porogen ratio, the salt particles average size, use of tetrahydrofuran to dissolve the pre-polymer for its injection in the porogen template, and the curing pressure. The effect of these variables on their structural, mechanical and biological properties was assessed to select those leading to optimal ones in terms of their potential performance in tissue engineering applications. es_ES
dc.description.sponsorship The authors acknowledge Spanish Ministerio de Economia y Competitividad through DPI2015-65401-C3-2-R project. The authors acknowledge the assistance and advice of the Electron Microscopy Service of the Universitat Politecnica de Valencia (Spain). es_ES
dc.language Inglés es_ES
dc.publisher Taylor & Francis es_ES
dc.relation.ispartof International Journal of Polymeric Materials es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Cell culture es_ES
dc.subject Mechanical modulus es_ES
dc.subject Poly(glycerol sebacate) es_ES
dc.subject Salt templates es_ES
dc.subject Scaffold es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title The effect of salt fusion processing variables on structural, physicochemical and biological properties of poly(glycerol sebacate) scaffolds es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1080/00914037.2019.1636247 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//DPI2015-65401-C3-2-R/ES/SOPORTES POLIMERICOS MULTIFUNCIONALES PARA CO-CULTIVO CELULAR INDIRECTO Y ESTIMULACION QUIMICA DESTINADOS A MIMETIZAR TEJIDO RENAL IN VITRO/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Vilariño, G.; Muñoz-Santa, A.; Conejero-Garcia, Á.; Vallés Lluch, A. (2020). The effect of salt fusion processing variables on structural, physicochemical and biological properties of poly(glycerol sebacate) scaffolds. International Journal of Polymeric Materials. 69(14):938-945. https://doi.org/10.1080/00914037.2019.1636247 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1080/00914037.2019.1636247 es_ES
dc.description.upvformatpinicio 938 es_ES
dc.description.upvformatpfin 945 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 69 es_ES
dc.description.issue 14 es_ES
dc.relation.pasarela S\393709 es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
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