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Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium

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Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium

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dc.contributor.author Ranjan, Rajesh es_ES
dc.contributor.author Das, Partha es_ES
dc.contributor.author Batabyal, Subhashish es_ES
dc.contributor.author Minj, Arpana Priyanka es_ES
dc.date.accessioned 2021-01-27T10:04:08Z
dc.date.available 2021-01-27T10:04:08Z
dc.date.issued 2020-12-30
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/160027
dc.description.abstract [EN] The present study was undertaken to explore the immunohistochemical localisation of TRPV6 calcium channels in rabbit gut epithelium that are actively involved in calcium absorption. To undertake the research, twelve apparently healthy adult female rabbits with a body weight between 1.0 to 1.5 kg were procured, acclimatised and divided into two groups: control and test. Both groups were kept on same feed along with exogenous calcium supplementation in test group animals only. The serum calcium level revealed that normally a high value of serum calcium is maintained in the rabbit as compared to other mammals, thus indicating that the homeostatic mechanism might be poorly developed. Immunohistochemistry and reverse transcription polymerase chain reaction analysis revealed that the caecum was the site of maximum calcium absorption in rabbit, followed by the duodenum and jejunum. The expression pattern of TRPV6 protein/mRNA was weaker in test group animals than in the control group, indicating that the channel was functional in low calcium concentration in the gut. es_ES
dc.description.sponsorship West Bengal University of Animal and Fishery Sciences es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València es_ES
dc.relation.ispartof World Rabbit Science es_ES
dc.rights Reconocimiento - No comercial - Compartir igual (by-nc-sa) es_ES
dc.subject Rabbit es_ES
dc.subject Gut epithelium es_ES
dc.subject TRPV6 es_ES
dc.subject Immunohistochemistry es_ES
dc.subject RT-PCR es_ES
dc.title Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.4995/wrs.2020.12161
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Ranjan, R.; Das, P.; Batabyal, S.; Minj, AP. (2020). Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium. World Rabbit Science. 28(4):187-197. https://doi.org/10.4995/wrs.2020.12161 es_ES
dc.description.accrualMethod OJS es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2020.12161 es_ES
dc.description.upvformatpinicio 187 es_ES
dc.description.upvformatpfin 197 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 28 es_ES
dc.description.issue 4 es_ES
dc.identifier.eissn 1989-8886
dc.relation.pasarela OJS\12161 es_ES
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