Mostrar el registro sencillo del ítem
dc.contributor.author | Estruch, Guillem | es_ES |
dc.contributor.author | Martínez-Llorens, Silvia | es_ES |
dc.contributor.author | Tomas-Vidal, A. | es_ES |
dc.contributor.author | Monge-Ortiz, Raquel | es_ES |
dc.contributor.author | Jover Cerda, Miguel | es_ES |
dc.contributor.author | Brown, Paul B. | es_ES |
dc.contributor.author | Peñaranda, D.S. | es_ES |
dc.date.accessioned | 2021-02-19T04:34:15Z | |
dc.date.available | 2021-02-19T04:34:15Z | |
dc.date.issued | 2020-03-30 | es_ES |
dc.identifier.issn | 1874-3919 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/161863 | |
dc.description.abstract | [EN] The digestive tract, particularly the intestine, represents one of the main sites of interactions with the environment, playing the gut mucosa a crucial role in the digestion and absorption of nutrients, and in the immune defence. Previous researches have proven that the fishmeal replacement by plant sources could have an impact on the intestinal status at both digestive and immune level, compromising relevant productive parameters, such as feed efficiency, growth or survival. In order to evaluate the long-term impact of total fishmeal replacement on intestinal mucosa, the gut mucosa proteome was analysed in fish fed with a fishmeal-based diet, against plant protein-based diets with or without alternative marine sources inclusion. Total fishmeal replacement without marine ingredients inclusion, reported a negative impact in growth and biometric parameters, further an altered gut mucosa proteome. However, the inclusion of a low percentage of marine ingredients in plant protein-based diets was able to maintain the growth, biometrics parameters and gut mucosa proteome with similar values to FM group. A total fishmeal replacement induced a big set of underrepresented proteins in relation to several biological processes such as intracellular transport, assembly of cellular macrocomplex, protein localization and protein catabolism, as well as several molecular functions, mainly related with binding to different molecules and the maintenance of the cytoskeleton structure. The set of downregulated proteins also included molecules which have a crucial role in the maintenance of the normal function of the enterocytes, and therefore, of the epithelium, including permeability, immune and inflammatory response regulation and nutritional absorption. Possibly, the amino acid imbalance presented in VM diet, in a long-term feeding, may be the main reason of these alterations, which can be prevented by the inclusion of 15% of alternative marine sources. Significance: Long-term feeding with plant protein based diets may be considered as a stress factor and lead to a negative impact on digestive and immune system mechanisms at the gut, that can become apparent in a reduced fish performance. The need for fishmeal replacement by alternative ingredients such as plant sources to ensure the sustainability of the aquaculture sector has led the research assessing the intestinal status of fish to be of increasing importance. This scientific work provides further knowledge about the proteins and biologic processes altered in the gut in response to plant protein based diets, suggesting the loss of part of gut mucosa functionality. Nevertheless, the inclusion of alternative marine ingredients was able to reverse these negative effects, showing as a feasible option to develop sustainable aquafeeds. | es_ES |
dc.description.sponsorship | The first author was supported by a contract-grant (Contrato Pre doctoral para la Formacion de Profesorado Universitario) from Subprogramas de Formacion y Movilidad within the Programa Estatal de Promocion del Talento y su Empleabilidad of the Ministerio de Educacion, Cultura y Deporte of Spain. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Journal of Proteomics | es_ES |
dc.rights | Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) | es_ES |
dc.subject | Gilthead seabream | es_ES |
dc.subject | Plant sources | es_ES |
dc.subject | Gut mucosa | es_ES |
dc.subject | Alternative marine ingredients | es_ES |
dc.subject | Proteome | es_ES |
dc.subject | Label-free LC-MS/MS assay | es_ES |
dc.subject.classification | PRODUCCION ANIMAL | es_ES |
dc.title | Impact of high dietary plant protein with or without marine ingredients in gut mucosa proteome of gilthead seabream (Sparus aurata, L.) | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.jprot.2020.103672 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MECD//FPU13%2F01278/ES/FPU13%2F01278/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal | es_ES |
dc.description.bibliographicCitation | Estruch, G.; Martínez-Llorens, S.; Tomas-Vidal, A.; Monge-Ortiz, R.; Jover Cerda, M.; Brown, PB.; Peñaranda, D. (2020). Impact of high dietary plant protein with or without marine ingredients in gut mucosa proteome of gilthead seabream (Sparus aurata, L.). Journal of Proteomics. 216:1-13. https://doi.org/10.1016/j.jprot.2020.103672 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.jprot.2020.103672 | es_ES |
dc.description.upvformatpinicio | 1 | es_ES |
dc.description.upvformatpfin | 13 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 216 | es_ES |
dc.identifier.pmid | 32004726 | es_ES |
dc.relation.pasarela | S\401461 | es_ES |
dc.contributor.funder | Ministerio de Educación, Cultura y Deporte | es_ES |
dc.description.references | Martínez-Llorens, S., Moñino, A. V., Tomás Vidal, A., Salvador, V. J. M., Pla Torres, M., & Jover Cerdá, M. (2007). Soybean meal as a protein source in gilthead sea bream (Sparus aurata L.) diets: effects on growth and nutrient utilization. Aquaculture Research, 38(1), 82-90. doi:10.1111/j.1365-2109.2006.01637.x | es_ES |
dc.description.references | Moutinho, S., Martínez-Llorens, S., Tomás-Vidal, A., Jover-Cerdá, M., Oliva-Teles, A., & Peres, H. (2017). Meat and bone meal as partial replacement for fish meal in diets for gilthead seabream ( Sparus aurata ) juveniles: Growth, feed efficiency, amino acid utilization, and economic efficiency. Aquaculture, 468, 271-277. doi:10.1016/j.aquaculture.2016.10.024 | es_ES |
dc.description.references | Piccolo, G., Iaconisi, V., Marono, S., Gasco, L., Loponte, R., Nizza, S., … Parisi, G. (2017). Effect of Tenebrio molitor larvae meal on growth performance, in vivo nutrients digestibility, somatic and marketable indexes of gilthead sea bream (Sparus aurata). Animal Feed Science and Technology, 226, 12-20. doi:10.1016/j.anifeedsci.2017.02.007 | es_ES |
dc.description.references | Nengas, I., Alexis, M. N., & Davies, S. J. (1999). High inclusion levels of poultry meals and related byproducts in diets for gilthead seabream Sparus aurata L. Aquaculture, 179(1-4), 13-23. doi:10.1016/s0044-8486(99)00148-9 | es_ES |
dc.description.references | Monge-Ortiz, R., Martínez-Llorens, S., Márquez, L., Moyano, F. J., Jover-Cerdá, M., & Tomás-Vidal, A. (2016). Potential use of high levels of vegetal proteins in diets for market-sized gilthead sea bream (Sparus aurata). Archives of Animal Nutrition, 70(2), 155-172. doi:10.1080/1745039x.2016.1141743 | es_ES |
dc.description.references | Sitjà-Bobadilla, A., Peña-Llopis, S., Gómez-Requeni, P., Médale, F., Kaushik, S., & Pérez-Sánchez, J. (2005). Effect of fish meal replacement by plant protein sources on non-specific defence mechanisms and oxidative stress in gilthead sea bream (Sparus aurata). Aquaculture, 249(1-4), 387-400. doi:10.1016/j.aquaculture.2005.03.031 | es_ES |
dc.description.references | Santigosa, E., Sánchez, J., Médale, F., Kaushik, S., Pérez-Sánchez, J., & Gallardo, M. A. (2008). Modifications of digestive enzymes in trout (Oncorhynchus mykiss) and sea bream (Sparus aurata) in response to dietary fish meal replacement by plant protein sources. Aquaculture, 282(1-4), 68-74. doi:10.1016/j.aquaculture.2008.06.007 | es_ES |
dc.description.references | Kiron, V. (2012). Fish immune system and its nutritional modulation for preventive health care. Animal Feed Science and Technology, 173(1-2), 111-133. doi:10.1016/j.anifeedsci.2011.12.015 | es_ES |
dc.description.references | Minghetti, M., Drieschner, C., Bramaz, N., Schug, H., & Schirmer, K. (2017). A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC. Cell Biology and Toxicology, 33(6), 539-555. doi:10.1007/s10565-017-9385-x | es_ES |
dc.description.references | Gómez, G. D., & Balcázar, J. L. (2008). A review on the interactions between gut microbiota and innate immunity of fish: Table 1. FEMS Immunology & Medical Microbiology, 52(2), 145-154. doi:10.1111/j.1574-695x.2007.00343.x | es_ES |
dc.description.references | Yu, Y., Sitaraman, S., & Gewirtz, A. T. (2004). Intestinal Epithelial Cell Regulation of Mucosal Inflammation. Immunologic Research, 29(1-3), 055-068. doi:10.1385/ir:29:1-3:055 | es_ES |
dc.description.references | Ivanov, A. I., Parkos, C. A., & Nusrat, A. (2010). Cytoskeletal Regulation of Epithelial Barrier Function During Inflammation. The American Journal of Pathology, 177(2), 512-524. doi:10.2353/ajpath.2010.100168 | es_ES |
dc.description.references | Lokman, P., & Symonds, J. (2014). Molecular and biochemical tricks of the research trade: -omics approaches in finfish aquaculture. New Zealand Journal of Marine and Freshwater Research, 48(3), 492-505. doi:10.1080/00288330.2014.928333 | es_ES |
dc.description.references | Forné, I., Abián, J., & Cerdà, J. (2009). Fish proteome analysis: Model organisms and non-sequenced species. PROTEOMICS, 10(4), 858-872. doi:10.1002/pmic.200900609 | es_ES |
dc.description.references | Rodrigues, P. M., Silva, T. S., Dias, J., & Jessen, F. (2012). PROTEOMICS in aquaculture: Applications and trends. Journal of Proteomics, 75(14), 4325-4345. doi:10.1016/j.jprot.2012.03.042 | es_ES |
dc.description.references | Pandey, A., & Mann, M. (2000). Proteomics to study genes and genomes. Nature, 405(6788), 837-846. doi:10.1038/35015709 | es_ES |
dc.description.references | Karpievitch, Y. V., Polpitiya, A. D., Anderson, G. A., Smith, R. D., & Dabney, A. R. (2010). Liquid chromatography mass spectrometry-based proteomics: Biological and technological aspects. The Annals of Applied Statistics, 4(4). doi:10.1214/10-aoas341 | es_ES |
dc.description.references | Ahmed, F., Kumar, G., Soliman, F. M., Adly, M. A., Soliman, H. A. M., El-Matbouli, M., & Saleh, M. (2019). Proteomics for understanding pathogenesis, immune modulation and host pathogen interactions in aquaculture. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 32, 100625. doi:10.1016/j.cbd.2019.100625 | es_ES |
dc.description.references | Sissener, N. H., Martin, S. A. M., Cash, P., Hevrøy, E. M., Sanden, M., & Hemre, G.-I. (2009). Proteomic Profiling of Liver from Atlantic Salmon (Salmo salar) Fed Genetically Modified Soy Compared to the Near-Isogenic non-GM Line. Marine Biotechnology, 12(3), 273-281. doi:10.1007/s10126-009-9214-1 | es_ES |
dc.description.references | Morais, S., Silva, T., Cordeiro, O., Rodrigues, P., Guy, D. R., Bron, J. E., … Tocher, D. R. (2012). Effects of genotype and dietary fish oil replacement with vegetable oil on the intestinal transcriptome and proteome of Atlantic salmon (Salmo salar). BMC Genomics, 13(1), 448. doi:10.1186/1471-2164-13-448 | es_ES |
dc.description.references | Martin, S. A. M., Cash, P., Blaney, S., & Houlihan, D. F. (2001). Fish Physiology and Biochemistry, 24(3), 259-270. doi:10.1023/a:1014015530045 | es_ES |
dc.description.references | Martin, S. A. M., Vilhelmsson, O., Médale, F., Watt, P., Kaushik, S., & Houlihan, D. F. (2003). Proteomic sensitivity to dietary manipulations in rainbow trout. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1651(1-2), 17-29. doi:10.1016/s1570-9639(03)00231-0 | es_ES |
dc.description.references | Vilhelmsson, O. T., Martin, S. A. M., Médale, F., Kaushik, S. J., & Houlihan, D. F. (2004). Dietary plant-protein substitution affects hepatic metabolism in rainbow trout (Oncorhynchus mykiss). British Journal of Nutrition, 92(1), 71-80. doi:10.1079/bjn20041176 | es_ES |
dc.description.references | Kumar, G., Hummel, K., Razzazi-Fazeli, E., & El-Matbouli, M. (2019). Modulation of posterior intestinal mucosal proteome in rainbow trout (Oncorhynchus mykiss) after Yersinia ruckeri infection. Veterinary Research, 50(1). doi:10.1186/s13567-019-0673-8 | es_ES |
dc.description.references | Rajan, B., Lokesh, J., Kiron, V., & Brinchmann, M. F. (2013). Differentially expressed proteins in the skin mucus of Atlantic cod (Gadus morhua) upon natural infection with Vibrio anguillarum. BMC Veterinary Research, 9(1). doi:10.1186/1746-6148-9-103 | es_ES |
dc.description.references | Saleh, M., Kumar, G., Abdel-Baki, A.-A., Dkhil, M. A., El-Matbouli, M., & Al-Quraishy, S. (2018). Quantitative shotgun proteomics distinguishes wound-healing biomarker signatures in common carp skin mucus in response to Ichthyophthirius multifiliis. Veterinary Research, 49(1). doi:10.1186/s13567-018-0535-9 | es_ES |
dc.description.references | Saleh, M., Kumar, G., Abdel-Baki, A.-A. S., Dkhil, M. A., El-Matbouli, M., & Al-Quraishy, S. (2019). Quantitative proteomic profiling of immune responses to Ichthyophthirius multifiliis in common carp skin mucus. Fish & Shellfish Immunology, 84, 834-842. doi:10.1016/j.fsi.2018.10.078 | es_ES |
dc.description.references | ENYU, Y.-L., & SHU-CHIEN, A. C. (2011). Proteomics analysis of mitochondrial extract from liver of female zebrafish undergoing starvation and refeeding. Aquaculture Nutrition, 17(2), e413-e423. doi:10.1111/j.1365-2095.2010.00776.x | es_ES |
dc.description.references | Boonanuntanasarn, S., Nakharuthai, C., Schrama, D., Duangkaew, R., & Rodrigues, P. M. (2019). Effects of dietary lipid sources on hepatic nutritive contents, fatty acid composition and proteome of Nile tilapia (Oreochromis niloticus). Journal of Proteomics, 192, 208-222. doi:10.1016/j.jprot.2018.09.003 | es_ES |
dc.description.references | Ghisaura, S., Anedda, R., Pagnozzi, D., Biosa, G., Spada, S., Bonaglini, E., … Addis, M. F. (2014). Impact of three commercial feed formulations on farmed gilthead sea bream (Sparus aurata, L.) metabolism as inferred from liver and blood serum proteomics. Proteome Science, 12(1). doi:10.1186/s12953-014-0044-3 | es_ES |
dc.description.references | Sabbagh, M., Schiavone, R., Brizzi, G., Sicuro, B., Zilli, L., & Vilella, S. (2019). Poultry by-product meal as an alternative to fish meal in the juvenile gilthead seabream (Sparus aurata) diet. Aquaculture, 511, 734220. doi:10.1016/j.aquaculture.2019.734220 | es_ES |
dc.description.references | Piazzon, M. C., Calduch-Giner, J. A., Fouz, B., Estensoro, I., Simó-Mirabet, P., Puyalto, M., … Pérez-Sánchez, J. (2017). Under control: how a dietary additive can restore the gut microbiome and proteomic profile, and improve disease resilience in a marine teleostean fish fed vegetable diets. Microbiome, 5(1). doi:10.1186/s40168-017-0390-3 | es_ES |
dc.description.references | Wulff, T., Petersen, J., Nørrelykke, M. R., Jessen, F., & Nielsen, H. H. (2012). Proteome Analysis of Pyloric Ceca: A Methodology for Fish Feed Development? Journal of Agricultural and Food Chemistry, 60(34), 8457-8464. doi:10.1021/jf3016943 | es_ES |
dc.description.references | Pérez-Sánchez, J., Estensoro, I., Redondo, M. J., Calduch-Giner, J. A., Kaushik, S., & Sitjà-Bobadilla, A. (2013). Mucins as Diagnostic and Prognostic Biomarkers in a Fish-Parasite Model: Transcriptional and Functional Analysis. PLoS ONE, 8(6), e65457. doi:10.1371/journal.pone.0065457 | es_ES |
dc.description.references | Mirghaed, A. T., Yarahmadi, P., Soltani, M., Paknejad, H., & Hoseini, S. M. (2019). Dietary sodium butyrate (Butirex® C4) supplementation modulates intestinal transcriptomic responses and augments disease resistance of rainbow trout (Oncorhynchus mykiss). Fish & Shellfish Immunology, 92, 621-628. doi:10.1016/j.fsi.2019.06.046 | es_ES |
dc.description.references | Estruch, G., Tomás-Vidal, A., El Nokrashy, A. M., Monge-Ortiz, R., Godoy-Olmos, S., Jover Cerdá, M., & Martínez-Llorens, S. (2018). Inclusion of alternative marine by-products in aquafeeds with different levels of plant-based sources for on-growing gilthead sea bream (Sparus aurata, L.): effects on digestibility, amino acid retention, ammonia excretion and enzyme activity. Archives of Animal Nutrition, 72(4), 321-339. doi:10.1080/1745039x.2018.1472408 | es_ES |
dc.description.references | Peres, H., & Oliva-Teles, A. (2009). The optimum dietary essential amino acid profile for gilthead seabream (Sparus aurata) juveniles. Aquaculture, 296(1-2), 81-86. doi:10.1016/j.aquaculture.2009.04.046 | es_ES |
dc.description.references | Cox, J., Hein, M. Y., Luber, C. A., Paron, I., Nagaraj, N., & Mann, M. (2014). Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ. Molecular & Cellular Proteomics, 13(9), 2513-2526. doi:10.1074/mcp.m113.031591 | es_ES |
dc.description.references | Metsalu, T., & Vilo, J. (2015). ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap. Nucleic Acids Research, 43(W1), W566-W570. doi:10.1093/nar/gkv468 | es_ES |
dc.description.references | Conesa, A., Gotz, S., Garcia-Gomez, J. M., Terol, J., Talon, M., & Robles, M. (2005). Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics, 21(18), 3674-3676. doi:10.1093/bioinformatics/bti610 | es_ES |
dc.description.references | Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2008). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols, 4(1), 44-57. doi:10.1038/nprot.2008.211 | es_ES |
dc.description.references | Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2008). Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Research, 37(1), 1-13. doi:10.1093/nar/gkn923 | es_ES |
dc.description.references | Kader, M. A., Bulbul, M., Koshio, S., Ishikawa, M., Yokoyama, S., Nguyen, B. T., & Komilus, C. F. (2012). Effect of complete replacement of fishmeal by dehulled soybean meal with crude attractants supplementation in diets for red sea bream, Pagrus major. Aquaculture, 350-353, 109-116. doi:10.1016/j.aquaculture.2012.04.009 | es_ES |
dc.description.references | HERBINGER, C. M., & FRIARS, G. W. (1991). Correlation between condition factor and total lipid content in Atlantic salmon, Salmo salar L., parr. Aquaculture Research, 22(4), 527-529. doi:10.1111/j.1365-2109.1991.tb00766.x | es_ES |
dc.description.references | Johansson, L., Kiessling, A., Kiessling, K.-H., & Berglund, L. (2000). Effects of altered ration levels on sensory characteristics, lipid content and fatty acid composition of rainbow trout (Oncorhynchus mykiss). Food Quality and Preference, 11(3), 247-254. doi:10.1016/s0950-3293(99)00073-7 | es_ES |
dc.description.references | De Francesco, M., Parisi, G., Médale, F., Lupi, P., Kaushik, S. J., & Poli, B. M. (2004). Effect of long-term feeding with a plant protein mixture based diet on growth and body/fillet quality traits of large rainbow trout (Oncorhynchus mykiss). Aquaculture, 236(1-4), 413-429. doi:10.1016/j.aquaculture.2004.01.006 | es_ES |
dc.description.references | Berg, O. K., Thronæs, E., & Bremset, G. (1998). Energetics and survival of virgin and repeat spawning brown trout (Salmo trutta). Canadian Journal of Fisheries and Aquatic Sciences, 55(1), 47-53. doi:10.1139/f97-208 | es_ES |
dc.description.references | Saera-Vila, A., Calduch-Giner, J. A., Gómez-Requeni, P., Médale, F., Kaushik, S., & Pérez-Sánchez, J. (2005). Molecular characterization of gilthead sea bream (Sparus aurata) lipoprotein lipase. Transcriptional regulation by season and nutritional condition in skeletal muscle and fat storage tissues. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 142(2), 224-232. doi:10.1016/j.cbpb.2005.07.009 | es_ES |
dc.description.references | Panserat, S., & Kaushik, S. J. (2010). Regulation of gene expression by nutritional factors in fish. Aquaculture Research, 41(5), 751-762. doi:10.1111/j.1365-2109.2009.02173.x | es_ES |
dc.description.references | Khurana, S., & George, S. P. (2008). Regulation of cell structure and function by actin-binding proteins: Villin’s perspective. FEBS Letters, 582(14), 2128-2139. doi:10.1016/j.febslet.2008.02.040 | es_ES |
dc.description.references | Bedford, L., Paine, S., Sheppard, P. W., Mayer, R. J., & Roelofs, J. (2010). Assembly, structure, and function of the 26S proteasome. Trends in Cell Biology, 20(7), 391-401. doi:10.1016/j.tcb.2010.03.007 | es_ES |
dc.description.references | Wu, Y.-X., Yang, J.-H., & Saitsu, H. (2016). Bortezomib-resistance is associated with increased levels of proteasome subunits and apoptosis-avoidance. Oncotarget, 7(47), 77622-77634. doi:10.18632/oncotarget.12731 | es_ES |
dc.description.references | Fararjeh, Chen, Ho, Cheng, Liu, Chang, … Tu. (2019). Proteasome 26S Subunit, non-ATPase 3 (PSMD3) Regulates Breast Cancer by Stabilizing HER2 from Degradation. Cancers, 11(4), 527. doi:10.3390/cancers11040527 | es_ES |
dc.description.references | Pastorelli, L., De Salvo, C., Mercado, J. R., Vecchi, M., & Pizarro, T. T. (2013). Central Role of the Gut Epithelial Barrier in the Pathogenesis of Chronic Intestinal Inflammation: Lessons Learned from Animal Models and Human Genetics. Frontiers in Immunology, 4. doi:10.3389/fimmu.2013.00280 | es_ES |
dc.description.references | Babbin, B. A., Laukoetter, M. G., Nava, P., Koch, S., Lee, W. Y., Capaldo, C. T., … Nusrat, A. (2008). Annexin A1 Regulates Intestinal Mucosal Injury, Inflammation, and Repair. The Journal of Immunology, 181(7), 5035-5044. doi:10.4049/jimmunol.181.7.5035 | es_ES |
dc.description.references | Leoni, G., Neumann, P.-A., Sumagin, R., Denning, T. L., & Nusrat, A. (2015). Wound repair: role of immune–epithelial interactions. Mucosal Immunology, 8(5), 959-968. doi:10.1038/mi.2015.63 | es_ES |
dc.description.references | Bakke-McKellep, A. M., Penn, M. H., Salas, P. M., Refstie, S., Sperstad, S., Landsverk, T., … Krogdahl, Å. (2007). Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.). British Journal of Nutrition, 97(4), 699-713. doi:10.1017/s0007114507381397 | es_ES |
dc.description.references | Wolf, H. K., & Dittrich, K. L. (1992). Detection of proliferating cell nuclear antigen in diagnostic histopathology. Journal of Histochemistry & Cytochemistry, 40(9), 1269-1273. doi:10.1177/40.9.1354677 | es_ES |
dc.description.references | Ducker, G. S., & Rabinowitz, J. D. (2017). One-Carbon Metabolism in Health and Disease. Cell Metabolism, 25(1), 27-42. doi:10.1016/j.cmet.2016.08.009 | es_ES |
dc.description.references | Cunningham, K. E., & Turner, J. R. (2012). Myosin light chain kinase: pulling the strings of epithelial tight junction function. Annals of the New York Academy of Sciences, 1258(1), 34-42. doi:10.1111/j.1749-6632.2012.06526.x | es_ES |
dc.description.references | Fanning, A. S., & Anderson, J. M. (1999). PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. Journal of Clinical Investigation, 103(6), 767-772. doi:10.1172/jci6509 | es_ES |
dc.description.references | Werner, T., & Haller, D. (2007). Intestinal epithelial cell signalling and chronic inflammation: From the proteome to specific molecular mechanisms. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 622(1-2), 42-57. doi:10.1016/j.mrfmmm.2007.05.010 | es_ES |
dc.description.references | Lee, S. H. (2015). Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases. Intestinal Research, 13(1), 11. doi:10.5217/ir.2015.13.1.11 | es_ES |
dc.description.references | Turner, J. R. (2009). Intestinal mucosal barrier function in health and disease. Nature Reviews Immunology, 9(11), 799-809. doi:10.1038/nri2653 | es_ES |
dc.description.references | Ulluwishewa, D., Anderson, R. C., McNabb, W. C., Moughan, P. J., Wells, J. M., & Roy, N. C. (2011). Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components. The Journal of Nutrition, 141(5), 769-776. doi:10.3945/jn.110.135657 | es_ES |
dc.description.references | Knudsen, D., Jutfelt, F., Sundh, H., Sundell, K., Koppe, W., & Frøkiær, H. (2008). Dietary soya saponins increase gut permeability and play a key role in the onset of soyabean-induced enteritis in Atlantic salmon (Salmo salar L.). British Journal of Nutrition, 100(1), 120-129. doi:10.1017/s0007114507886338 | es_ES |
dc.description.references | Hu, H., Kortner, T. M., Gajardo, K., Chikwati, E., Tinsley, J., & Krogdahl, Å. (2016). Intestinal Fluid Permeability in Atlantic Salmon (Salmo salar L.) Is Affected by Dietary Protein Source. PLOS ONE, 11(12), e0167515. doi:10.1371/journal.pone.0167515 | es_ES |
dc.description.references | Strober, W., Fuss, I. J., & Blumberg, R. S. (2002). The Immunology of Mucosal Models of Inflammation. Annual Review of Immunology, 20(1), 495-549. doi:10.1146/annurev.immunol.20.100301.064816 | es_ES |
dc.description.references | Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004). Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis. Cell, 118(2), 229-241. doi:10.1016/j.cell.2004.07.002 | es_ES |
dc.description.references | Neal, M. D., Leaphart, C., Levy, R., Prince, J., Billiar, T. R., Watkins, S., … Hackam, D. J. (2006). Enterocyte TLR4 Mediates Phagocytosis and Translocation of Bacteria Across the Intestinal Barrier. The Journal of Immunology, 176(5), 3070-3079. doi:10.4049/jimmunol.176.5.3070 | es_ES |
dc.description.references | Fink, M. P., & Delude, R. L. (2005). Epithelial Barrier Dysfunction: A Unifying Theme to Explain the Pathogenesis of Multiple Organ Dysfunction at the Cellular Level. Critical Care Clinics, 21(2), 177-196. doi:10.1016/j.ccc.2005.01.005 | es_ES |
dc.description.references | Estruch, G., Collado, M. C., Peñaranda, D. S., Tomás Vidal, A., Jover Cerdá, M., Pérez Martínez, G., & Martinez-Llorens, S. (2015). Impact of Fishmeal Replacement in Diets for Gilthead Sea Bream (Sparus aurata) on the Gastrointestinal Microbiota Determined by Pyrosequencing the 16S rRNA Gene. PLOS ONE, 10(8), e0136389. doi:10.1371/journal.pone.0136389 | es_ES |
dc.description.references | Snelgrove, R. J. (2011). Leukotriene A4 hydrolase: an anti-inflammatory role for a proinflammatory enzyme. Thorax, 66(6), 550-551. doi:10.1136/thoraxjnl-2011-200234 | es_ES |
dc.description.references | Banerjee, S., Oneda, B., Yap, L. M., Jewell, D. P., Matters, G. L., Fitzpatrick, L. R., … Bond, J. S. (2009). MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal Immunology, 2(3), 220-231. doi:10.1038/mi.2009.3 | es_ES |
dc.description.references | Hashimoto, T., Perlot, T., Rehman, A., Trichereau, J., Ishiguro, H., Paolino, M., … Penninger, J. M. (2012). ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature, 487(7408), 477-481. doi:10.1038/nature11228 | es_ES |
dc.description.references | Kokou, F., Sarropoulou, E., Cotou, E., Kentouri, M., Alexis, M., & Rigos, G. (2017). Effects of graded dietary levels of soy protein concentrate supplemented with methionine and phosphate on the immune and antioxidant responses of gilthead sea bream ( Sparus aurata L.). Fish & Shellfish Immunology, 64, 111-121. doi:10.1016/j.fsi.2017.03.017 | es_ES |
dc.description.references | Kokou, F., Sarropoulou, E., Cotou, E., Rigos, G., Henry, M., Alexis, M., & Kentouri, M. (2015). Effects of Fish Meal Replacement by a Soybean Protein on Growth, Histology, Selected Immune and Oxidative Status Markers of Gilthead Sea Bream, Sparus aurata. Journal of the World Aquaculture Society, 46(2), 115-128. doi:10.1111/jwas.12181 | es_ES |
dc.description.references | Tort, L. (2011). Stress and immune modulation in fish. Developmental & Comparative Immunology, 35(12), 1366-1375. doi:10.1016/j.dci.2011.07.002 | es_ES |
dc.description.references | Burrells, C., Williams, P. D., Southgate, P. J., & Crampton, V. O. (1999). Immunological, physiological and pathological responses of rainbow trout (Oncorhynchus mykiss) to increasing dietary concentrations of soybean proteins. Veterinary Immunology and Immunopathology, 72(3-4), 277-288. doi:10.1016/s0165-2427(99)00143-9 | es_ES |
dc.description.references | Estruch, G., Collado, M. C., Monge-Ortiz, R., Tomás-Vidal, A., Jover-Cerdá, M., Peñaranda, D. S., … Martínez-Llorens, S. (2018). Long-term feeding with high plant protein based diets in gilthead seabream (Sparus aurata, L.) leads to changes in the inflammatory and immune related gene expression at intestinal level. BMC Veterinary Research, 14(1). doi:10.1186/s12917-018-1626-6 | es_ES |
dc.description.references | Estensoro, I., Ballester-Lozano, G., Benedito-Palos, L., Grammes, F., Martos-Sitcha, J. A., Mydland, L.-T., … Pérez-Sánchez, J. (2016). Dietary Butyrate Helps to Restore the Intestinal Status of a Marine Teleost (Sparus aurata) Fed Extreme Diets Low in Fish Meal and Fish Oil. PLOS ONE, 11(11), e0166564. doi:10.1371/journal.pone.0166564 | es_ES |
dc.description.references | Baeza-Ariño, R., Martínez-Llorens, S., Nogales-Mérida, S., Jover-Cerda, M., & Tomás-Vidal, A. (2014). Study of liver and gut alterations in sea bream,Sparus aurataL., fed a mixture of vegetable protein concentrates. Aquaculture Research, 47(2), 460-471. doi:10.1111/are.12507 | es_ES |
dc.description.references | Bakke-McKellep, A. M., Nordrum, S., Krogdahl, Å., & Buddington, R. K. (2000). Fish Physiology and Biochemistry, 22(1), 33-44. doi:10.1023/a:1007872929847 | es_ES |
dc.description.references | Ambardekar, A. A., Reigh, R. C., & Williams, M. B. (2009). Absorption of amino acids from intact dietary proteins and purified amino acid supplements follows different time-courses in channel catfish (Ictalurus punctatus). Aquaculture, 291(3-4), 179-187. doi:10.1016/j.aquaculture.2009.02.044 | es_ES |
dc.description.references | Santigosa, E., García-Meilán, I., Valentin, J. M., Pérez-Sánchez, J., Médale, F., Kaushik, S., & Gallardo, M. A. (2011). Modifications of intestinal nutrient absorption in response to dietary fish meal replacement by plant protein sources in sea bream (Sparus aurata) and rainbow trout (Onchorynchus mykiss). Aquaculture, 317(1-4), 146-154. doi:10.1016/j.aquaculture.2011.04.026 | es_ES |
dc.description.references | Dhabhar, F. S. (2009). Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology. Neuroimmunomodulation, 16(5), 300-317. doi:10.1159/000216188 | es_ES |
dc.description.references | Gong, H., Lawrence, A. L., Jiang, D.-H., Castille, F. L., & Gatlin, D. M. (2000). Lipid nutrition of juvenile Litopenaeus vannamei. Aquaculture, 190(3-4), 305-324. doi:10.1016/s0044-8486(00)00414-2 | es_ES |
dc.description.references | Schrama, D., Richard, N., Silva, T. S., Figueiredo, F. A., Conceição, L. E. C., Burchmore, R., … Rodrigues, P. M. L. (2016). Enhanced dietary formulation to mitigate winter thermal stress in gilthead sea bream (Sparus aurata): a 2D-DIGE plasma proteome study. Fish Physiology and Biochemistry, 43(2), 603-617. doi:10.1007/s10695-016-0315-2 | es_ES |
dc.subject.ods | 14.- Conservar y utilizar de forma sostenible los océanos, mares y recursos marinos para lograr el desarrollo sostenible | es_ES |