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Biosensors for food allergy detection according to specific IgE levels in serum

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Morais, S.; Tortajada-Genaro, LA.; Maquieira Catala, Á.; González Martínez, MÁ. (2020). Biosensors for food allergy detection according to specific IgE levels in serum. TrAC Trends in Analytical Chemistry. 127:1-12. https://doi.org/10.1016/j.trac.2020.115904

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Title: Biosensors for food allergy detection according to specific IgE levels in serum
Author: Morais, Sergi Tortajada-Genaro, Luis Antonio Maquieira Catala, Ángel González Martínez, Miguel Ángel
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
[EN] People respond differently to food components, which can sometimes cause dramatic and unpredictable effects, such as intolerance, toxicity and allergy, and are a major global problem today. Of all the different reactions ...[+]
Subjects: Biosensing , Food allergens , IgE , Diagnostics , In vitro point-of-care
Copyrigths: Cerrado
TrAC Trends in Analytical Chemistry. (issn: 0165-9936 )
DOI: 10.1016/j.trac.2020.115904
Publisher version: https://doi.org/10.1016/j.trac.2020.115904
Project ID:
We thank the Spanish Ministry of Economy and Competitiveness (CTQ2016-75749-R), FEDER and the European Union's Horizon 2020 research and innovation programme for funding Grant No. 688448 (Compact biophotonics platform for ...[+]
Type: Artículo


Muraro, A., Werfel, T., Hoffmann-Sommergruber, K., Roberts, G., Beyer, K., … Bindslev-Jensen, C. (2014). EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy. Allergy, 69(8), 1008-1025. doi:10.1111/all.12429

Sampson, H. A. (2005). Food allergy - accurately identifying clinical reactivity. Allergy, 60, 19-24. doi:10.1111/j.1398-9995.2005.00853.x

Barnett, J., Vasileiou, K., & Lucas, J. S. (2020). Conversations about food allergy risk with restaurant staff when eating out: A customer perspective. Food Control, 108, 106858. doi:10.1016/j.foodcont.2019.106858 [+]
Muraro, A., Werfel, T., Hoffmann-Sommergruber, K., Roberts, G., Beyer, K., … Bindslev-Jensen, C. (2014). EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy. Allergy, 69(8), 1008-1025. doi:10.1111/all.12429

Sampson, H. A. (2005). Food allergy - accurately identifying clinical reactivity. Allergy, 60, 19-24. doi:10.1111/j.1398-9995.2005.00853.x

Barnett, J., Vasileiou, K., & Lucas, J. S. (2020). Conversations about food allergy risk with restaurant staff when eating out: A customer perspective. Food Control, 108, 106858. doi:10.1016/j.foodcont.2019.106858

Sicherer, S. H., & Sampson, H. A. (2018). Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. Journal of Allergy and Clinical Immunology, 141(1), 41-58. doi:10.1016/j.jaci.2017.11.003

Martino, D. J., Saffery, R., Allen, K. J., & Prescott, S. L. (2016). Epigenetic modifications: mechanisms of disease and biomarkers of food allergy. Current Opinion in Immunology, 42, 9-15. doi:10.1016/j.coi.2016.05.005

Lack, G. (2012). Update on risk factors for food allergy. Journal of Allergy and Clinical Immunology, 129(5), 1187-1197. doi:10.1016/j.jaci.2012.02.036

Turner, P. J., Campbell, D. E., Boyle, R. J., & Levin, M. E. (2018). Primary Prevention of Food Allergy: Translating Evidence from Clinical Trials to Population-Based Recommendations. The Journal of Allergy and Clinical Immunology: In Practice, 6(2), 367-375. doi:10.1016/j.jaip.2017.12.015

Kumfer, A. M., & Commins, S. P. (2019). Primary Prevention of Food Allergy. Current Allergy and Asthma Reports, 19(1). doi:10.1007/s11882-019-0838-6

Burks, A. W., Tang, M., Sicherer, S., Muraro, A., Eigenmann, P. A., Ebisawa, M., … Sampson, H. A. (2012). ICON: Food allergy. Journal of Allergy and Clinical Immunology, 129(4), 906-920. doi:10.1016/j.jaci.2012.02.001

Ho, M. H.-K., Wong, W. H.-S., & Chang, C. (2012). Clinical Spectrum of Food Allergies: a Comprehensive Review. Clinical Reviews in Allergy & Immunology, 46(3), 225-240. doi:10.1007/s12016-012-8339-6

Tanno, L. K., Calderon, M. A., Goldberg, B. J., Akdis, C. A., Papadopoulos, N. G., & Demoly, P. (2014). Categorization of allergic disorders in the new World Health Organization International Classification of Diseases. Clinical and Translational Allergy, 4(1), 42. doi:10.1186/2045-7022-4-42

Longo, G., Berti, I., Burks, A. W., Krauss, B., & Barbi, E. (2013). IgE-mediated food allergy in children. The Lancet, 382(9905), 1656-1664. doi:10.1016/s0140-6736(13)60309-8

Du Toit, G., Sampson, H. A., Plaut, M., Burks, A. W., Akdis, C. A., & Lack, G. (2018). Food allergy: Update on prevention and tolerance. Journal of Allergy and Clinical Immunology, 141(1), 30-40. doi:10.1016/j.jaci.2017.11.010

Tang, M. L. K., & Mullins, R. J. (2017). Food allergy: is prevalence increasing? Internal Medicine Journal, 47(3), 256-261. doi:10.1111/imj.13362

Sicherer, S. H. (2002). Food allergy. The Lancet, 360(9334), 701-710. doi:10.1016/s0140-6736(02)09831-8

Anvari, S., Miller, J., Yeh, C.-Y., & Davis, C. M. (2018). IgE-Mediated Food Allergy. Clinical Reviews in Allergy & Immunology, 57(2), 244-260. doi:10.1007/s12016-018-8710-3

Ciprandi, G. (2017). Serum IgE as biomarker for predicting allergen immunotherapy effectiveness. Journal of Allergy and Clinical Immunology, 139(6), 2029. doi:10.1016/j.jaci.2016.12.987

Brockow, K., Garvey, L. H., Aberer, W., Atanaskovic-Markovic, M., Barbaud, A., … Bilo, M. B. (2013). Skin test concentrations for systemically administered drugs - an ENDA/EAACI Drug Allergy Interest Group position paper. Allergy, 68(6), 702-712. doi:10.1111/all.12142

Demoly, P., Adkinson, N. F., Brockow, K., Castells, M., Chiriac, A. M., Greenberger, P. A., … Thong, B. Y.-H. (2014). International Consensus on drug allergy. Allergy, 69(4), 420-437. doi:10.1111/all.12350

Hemmings, O., Kwok, M., McKendry, R., & Santos, A. F. (2018). Basophil Activation Test: Old and New Applications in Allergy. Current Allergy and Asthma Reports, 18(12). doi:10.1007/s11882-018-0831-5

Rubio, M., Bousquet, P.-J., & Demoly, P. (2010). Update in drug allergy: novel drugs with novel reaction patterns. Current Opinion in Allergy & Clinical Immunology, 10(5), 457-462. doi:10.1097/aci.0b013e32833e0896

Diaz-Vazquez, C., Torregrosa-Bertet, M. J., Carvajal-Urueña, I., Cano-Garcinuño, A., Fos-Escrivà, E., García-Gallego, A., … Ridao-Redondo, M. L. (2009). Accuracy of ImmunoCAP®Rapid in the diagnosis of allergic sensitization in children between 1 and 14 years with recurrent wheezing: The IReNE study. Pediatric Allergy and Immunology, 20(6), 601-609. doi:10.1111/j.1399-3038.2008.00827.x

Chinnasamy, T., Segerink, L. I., Nystrand, M., Gantelius, J., & Svahn, H. A. (2014). A lateral flow paper microarray for rapid allergy point of care diagnostics. The Analyst, 139(10), 2348. doi:10.1039/c3an01806g

Reuterswärd, P., Gantelius, J., & Andersson Svahn, H. (2015). An 8 minute colorimetric paper-based reverse phase vertical flow serum microarray for screening of hyper IgE syndrome. The Analyst, 140(21), 7327-7334. doi:10.1039/c5an01013f

Oh, J. H., Park, M. K., Kim, S. W., & Park, J.-K. (2015). A fully automated analyzer for multiple detection of allergen-specific immunoglobulin E. Analytical Methods, 7(20), 8889-8895. doi:10.1039/c5ay01634g

Jiang, P., He, M., Shen, L., Shi, A., & Liu, Z. (2017). A paper-supported aptasensor for total IgE based on luminescence resonance energy transfer from upconversion nanoparticles to carbon nanoparticles. Sensors and Actuators B: Chemical, 239, 319-324. doi:10.1016/j.snb.2016.08.005

Liu, H., Malhotra, R., Peczuh, M. W., & Rusling, J. F. (2010). Electrochemical Immunosensors for Antibodies to Peanut Allergen Ara h2 Using Gold Nanoparticle−Peptide Films. Analytical Chemistry, 82(13), 5865-5871. doi:10.1021/ac101110q

Wang, Y., Cui, M., Jiao, M., & Luo, X. (2018). Antifouling and ultrasensitive biosensing interface based on self-assembled peptide and aptamer on macroporous gold for electrochemical detection of immunoglobulin E in serum. Analytical and Bioanalytical Chemistry, 410(23), 5871-5878. doi:10.1007/s00216-018-1201-9

PAPAMICHAEL, K., KREUZER, M., & GUILBAULT, G. (2007). Viability of allergy (IgE) detection using an alternative aptamer receptor and electrochemical means. Sensors and Actuators B: Chemical, 121(1), 178-186. doi:10.1016/j.snb.2006.09.024

Deinhofer, K., Sevcik, H., Balic, N., Harwanegg, C., Hiller, R., Rumpold, H., … Spitzauer, S. (2004). Microarrayed allergens for IgE profiling. Methods, 32(3), 249-254. doi:10.1016/j.ymeth.2003.08.018

King, E.-M., Vailes, L. D., Tsay, A., Satinover, S. M., & Chapman, M. D. (2007). Simultaneous detection of total and allergen-specific IgE by using purified allergens in a fluorescent multiplex array. Journal of Allergy and Clinical Immunology, 120(5), 1126-1131. doi:10.1016/j.jaci.2007.06.043

Gaudin, J.-C., Rabesona, H., Choiset, Y., Yeretssian, G., Chobert, J.-M., Sakanyan, V., … Haertlé, T. (2008). Assessment of the immunoglobulin E-mediated immune response to milk-specific proteins in allergic patients using microarrays. Clinical & Experimental Allergy, 38(4), 686-693. doi:10.1111/j.1365-2222.2008.02952.x

Lebrun, S. J., Petchpud, W. N., Hui, A., & McLaughlin, C. S. (2005). Development of a sensitive, colorometric microarray assay for allergen-responsive human IgE. Journal of Immunological Methods, 300(1-2), 24-31. doi:10.1016/j.jim.2005.01.019

Matsumoto, N., Okochi, M., Matsushima, M., Kato, R., Takase, T., Yoshida, Y., … Honda, H. (2009). Peptide array-based analysis of the specific IgE and IgG4 in cow’s milk allergens and its use in allergy evaluation. Peptides, 30(10), 1840-1847. doi:10.1016/j.peptides.2009.07.005

Shreffler, W. G., Beyer, K., Chu, T.-H. T., Burks, A. W., & Sampson, H. A. (2004). Microarray immunoassay: Association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes. Journal of Allergy and Clinical Immunology, 113(4), 776-782. doi:10.1016/j.jaci.2003.12.588

Renault, N. K., Gaddipati, S. R., Wulfert, F., Falcone, F. H., Mirotti, L., Tighe, P. J., … Alcocer, M. J. C. (2011). Multiple protein extract microarray for profiling human food-specific immunoglobulins A, M, G and E. Journal of Immunological Methods, 364(1-2), 21-32. doi:10.1016/j.jim.2010.10.004

Cretich, M., Breda, D., Damin, F., Borghi, M., Sola, L., Unlu, S. M., … Chiari, M. (2010). Allergen microarrays on high-sensitivity silicon slides. Analytical and Bioanalytical Chemistry, 398(4), 1723-1733. doi:10.1007/s00216-010-4077-x


Monroe, M. R., Reddington, A. P., Collins, A. D., LaBoda, C., Cretich, M., Chiari, M., … Ünlü, M. S. (2011). Multiplexed Method to Calibrate and Quantitate Fluorescence Signal for Allergen-Specific IgE. Analytical Chemistry, 83(24), 9485-9491. doi:10.1021/ac202212k

Morais, S., Puchades, R., & Maquieira, Á. (2016). Disc-based microarrays: principles and analytical applications. Analytical and Bioanalytical Chemistry, 408(17), 4523-4534. doi:10.1007/s00216-016-9423-1

Feyzkhanova, G. U., Filippova, M. A., Talibov, V. O., Dementieva, E. I., Maslennikov, V. V., Reznikov, Y. P., … Fooke-Achterrath, M. (2014). Development of hydrogel biochip for in vitro allergy diagnostics. Journal of Immunological Methods, 406, 51-57. doi:10.1016/j.jim.2014.03.003

Feyzkhanova, G., Voloshin, S., Smoldovskaya, O., Arefieva, A., Filippova, M., Barsky, V., … Rubina, A. (2017). Development of a microarray-based method for allergen-specific IgE and IgG4 detection. Clinical Proteomics, 14(1). doi:10.1186/s12014-016-9136-7

Syedmoradi, L., Daneshpour, M., Alvandipour, M., Gomez, F. A., Hajghassem, H., & Omidfar, K. (2017). Point of care testing: The impact of nanotechnology. Biosensors and Bioelectronics, 87, 373-387. doi:10.1016/j.bios.2016.08.084

Caracciolo, G., Vali, H., Moore, A., & Mahmoudi, M. (2019). Challenges in molecular diagnostic research in cancer nanotechnology. Nano Today, 27, 6-10. doi:10.1016/j.nantod.2019.06.001

Märki, I., & Rebeaud, F. (2017). Nanotechnologies for In Vitro IgE Testing. Current Allergy and Asthma Reports, 17(7). doi:10.1007/s11882-017-0717-y

Guesdon, J.-L., Thierry, R., & Avraméas, S. (1978). Magnetic enzyme immunoassay for measuring human IgE. Journal of Allergy and Clinical Immunology, 61(1), 23-27. doi:10.1016/0091-6749(78)90469-4

Ashraf, S., Qadri, S., al-Ramadi, B., & Haik, Y. (2012). Nanoparticles rapidly assess specific IgE in plasma. Nanotechnology, 23(30), 305101. doi:10.1088/0957-4484/23/30/305101

Yescas González, T., Leonard, A., Gaude, V., Delplanque, A., Barre, A., Rougé, P., … Peyrade, D. (2019). IgE detection in allergic patient’s serum by absorption analysis of biofunctionalised microparticles. Microelectronic Engineering, 207, 27-32. doi:10.1016/j.mee.2018.12.005

Teste, B., Malloggi, F., Siaugue, J.-M., Varenne, A., Kanoufi, F., & Descroix, S. (2011). Microchip integrating magnetic nanoparticles for allergy diagnosis. Lab on a Chip, 11(24), 4207. doi:10.1039/c1lc20809h

Proczek, G., Gassner, A.-L., Busnel, J.-M., & Girault, H. H. (2011). Total serum IgE quantification by microfluidic ELISA using magnetic beads. Analytical and Bioanalytical Chemistry, 402(8), 2645-2653. doi:10.1007/s00216-011-5495-0

Wang, J., Munir, A., Li, Z., & Zhou, H. S. (2009). Aptamer–Au NPs conjugates-enhanced SPR sensing for the ultrasensitive sandwich immunoassay. Biosensors and Bioelectronics, 25(1), 124-129. doi:10.1016/j.bios.2009.06.016

Li, H., Qiang, W., Vuki, M., Xu, D., & Chen, H.-Y. (2011). Fluorescence Enhancement of Silver Nanoparticle Hybrid Probes and Ultrasensitive Detection of IgE. Analytical Chemistry, 83(23), 8945-8952. doi:10.1021/ac201574s

Peng, Q., Cao, Z., Lau, C., Kai, M., & Lu, J. (2011). Aptamer-barcode based immunoassay for the instantaneous derivatization chemiluminescence detection of IgE coupled to magnetic beads. The Analyst, 136(1), 140-147. doi:10.1039/c0an00448k

Platt, G. W., Damin, F., Swann, M. J., Metton, I., Skorski, G., Cretich, M., & Chiari, M. (2014). Allergen immobilisation and signal amplification by quantum dots for use in a biosensor assay of IgE in serum. Biosensors and Bioelectronics, 52, 82-88. doi:10.1016/j.bios.2013.08.019

Cho, S., Lee, S. M., Shin, H. Y., Kim, M. S., Seo, Y. H., Cho, Y. K., … Kim, M. I. (2018). Highly sensitive colorimetric detection of allergies based on an immunoassay using peroxidase-mimicking nanozymes. The Analyst, 143(5), 1182-1187. doi:10.1039/c7an01866e

D. Howes, P., Rana, S., & M. Stevens, M. (2014). Plasmonic nanomaterials for biodiagnostics. Chem. Soc. Rev., 43(11), 3835-3853. doi:10.1039/c3cs60346f

Bose, P. P., Mandal, G., Chatterjee, U., Singh, M., & Chatterjee, B. P. (2016). Gold nanoparticle-based novel visual diagnostic method for the detection of specific IgE to test for food allergies. Analytical Methods, 8(19), 3878-3884. doi:10.1039/c5ay03387j

Li, Z., Li, Z., Niu, Q., Li, H., Vuki, M., & Xu, D. (2017). Visual microarray detection for human IgE based on silver nanoparticles. Sensors and Actuators B: Chemical, 239, 45-51. doi:10.1016/j.snb.2016.07.142

Zhou, J., Qi, Q., Wang, C., Qian, Y., Liu, G., Wang, Y., & Fu, L. (2019). Surface plasmon resonance (SPR) biosensors for food allergen detection in food matrices. Biosensors and Bioelectronics, 142, 111449. doi:10.1016/j.bios.2019.111449

SU, X., & ZHANG, J. (2004). Comparison of surface plasmon resonance spectroscopy and quartz crystal microbalance for human IgE quantification. Sensors and Actuators B: Chemical, 100(3), 309-314. doi:10.1016/j.snb.2004.01.020

Kim, Y. H., Kim, J. P., Han, S. J., & Sim, S. J. (2009). Aptamer biosensor for lable-free detection of human immunoglobulin E based on surface plasmon resonance. Sensors and Actuators B: Chemical, 139(2), 471-475. doi:10.1016/j.snb.2009.03.013

Kim, S., Lee, J., Lee, S. J., & Lee, H. J. (2010). Ultra-sensitive detection of IgE using biofunctionalized nanoparticle-enhanced SPR. Talanta, 81(4-5), 1755-1759. doi:10.1016/j.talanta.2010.03.036

Kim, B., Eggel, A., Tarchevskaya, S. S., Vogel, M., Prinz, H., & Jardetzky, T. S. (2012). Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor. Nature, 491(7425), 613-617. doi:10.1038/nature11546

Zellweger, F., Gasser, P., Brigger, D., Buschor, P., Vogel, M., & Eggel, A. (2017). A novel bispecific DARPin targeting FcγRIIB and FcεRI-bound IgE inhibits allergic responses. Allergy, 72(8), 1174-1183. doi:10.1111/all.13109

Suzuki, H., Yanase, Y., Tsutsui, T., Ishii, K., Hiragun, T., & Hide, M. (2008). Applying Surface Plasmon Resonance to Monitor the IgE-Mediated Activation of Human Basophils. Allergology International, 57(4), 347-358. doi:10.2332/allergolint.o-07-506

Joshi, A. A., Peczuh, M. W., Kumar, C. V., & Rusling, J. F. (2014). Ultrasensitive carbohydrate-peptide SPR imaging microarray for diagnosing IgE mediated peanut allergy. The Analyst, 139(22), 5728-5733. doi:10.1039/c4an01544d

Shen, M., Joshi, A. A., Vannam, R., Dixit, C. K., Hamilton, R. G., Kumar, C. V., … Peczuh, M. W. (2018). Epitope‐Resolved Detection of Peanut‐Specific IgE Antibodies by Surface Plasmon Resonance Imaging. ChemBioChem, 19(3), 199-202. doi:10.1002/cbic.201700513

Chardin, H., Mercier, K., Frydman, C., & Vollmer, N. (2014). Surface Plasmon Resonance imaging: A method to measure the affinity of the antibodies in allergy diagnosis. Journal of Immunological Methods, 405, 23-28. doi:10.1016/j.jim.2013.12.010

Espinosa, R., Laguna, M., Fernández, F., Santamaria, B., Sanza, F., Maigler, M., … Holgado, M. (2018). A Proof-of-Concept of Label-Free Biosensing System for Food Allergy Diagnostics in Biophotonic Sensing Cells: Performance Comparison with ImmunoCAP. Sensors, 18(8), 2686. doi:10.3390/s18082686

Luka, G., Ahmadi, A., Najjaran, H., Alocilja, E., DeRosa, M., Wolthers, K., … Hoorfar, M. (2015). Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications. Sensors, 15(12), 30011-30031. doi:10.3390/s151229783

Peoples, M. C., & Karnes, H. T. (2008). Microfluidic immunoaffinity separations for bioanalysis. Journal of Chromatography B, 866(1-2), 14-25. doi:10.1016/j.jchromb.2007.08.030

Ho, H., Lau, P., Kwok, H., Wu, S., Gao, M., Cheung, A. K., … Kong, S. (2014). Allergen screening bioassays: recent developments in lab-on-a-chip and lab-on-a-disc systems. Bioanalysis, 6(14), 2005-2018. doi:10.4155/bio.14.153

Robinson, A. J., Kashanin, D., O’Dowd, F., Fitzgerald, K., Williams, V., & Walsh, G. M. (2009). Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions. Clinical & Experimental Allergy, 39(12), 1866-1874. doi:10.1111/j.1365-2222.2009.03334.x

Chen, Q. L., Cheung, K. L., Kong, S. K., Zhou, J. Q., Kwan, Y. W., Wong, C. K., & Ho, H. P. (2012). An integrated lab-on-a-disc for automated cell-based allergen screening bioassays. Talanta, 97, 48-54. doi:10.1016/j.talanta.2012.03.061

Aljadi, Z., Kalm, F., Nilsson, C., Winqvist, O., Russom, A., Lundahl, J., & Nopp, A. (2019). A novel tool for clinical diagnosis of allergy operating a microfluidic immunoaffinity basophil activation test technique. Clinical Immunology, 209, 108268. doi:10.1016/j.clim.2019.108268

Heyries, K. A., Loughran, M. G., Hoffmann, D., Homsy, A., Blum, L. J., & Marquette, C. A. (2008). Microfluidic biochip for chemiluminescent detection of allergen-specific antibodies. Biosensors and Bioelectronics, 23(12), 1812-1818. doi:10.1016/j.bios.2008.02.025

Shyur, S.-D., Jan, R.-L., Webster, J. R., Chang, P., Lu, Y.-J., & Wang, J.-Y. (2009). Determination of multiple allergen-specific IgE by microfluidic immunoassay cartridge in clinical settings. Pediatric Allergy and Immunology, 21(4p1), 623-633. doi:10.1111/j.1399-3038.2009.00956.x

Cretich, M., Di Carlo, G., Giudici, C., Pokoj, S., Lauer, I., Scheurer, S., & Chiari, M. (2009). Detection of allergen specific immunoglobulins by microarrays coupled to microfluidics. PROTEOMICS, 9(8), 2098-2107. doi:10.1002/pmic.200800651

Tai, L.-W., Tseng, K.-Y., Wang, S.-T., Chiu, C.-C., Kow, C. H., Chang, P., … Webster, J. R. (2009). An automated microfluidic-based immunoassay cartridge for allergen screening and other multiplexed assays. Analytical Biochemistry, 391(2), 98-105. doi:10.1016/j.ab.2009.05.009

Huang, W.-Y., Chou, S.-T., Chen, C.-H., Chou, S.-Y., Wu, J.-H., Chen, Y.-C., & Lee, G.-B. (2018). An automatic integrated microfluidic system for allergy microarray chips. The Analyst, 143(10), 2285-2292. doi:10.1039/c8an00247a




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