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Covert Cognition in Disorders of Consciousness: A Meta-Analysis

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Covert Cognition in Disorders of Consciousness: A Meta-Analysis

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dc.contributor.author Schnakers, Caroline es_ES
dc.contributor.author Hirsch, Michaela es_ES
dc.contributor.author Noé, Enrique es_ES
dc.contributor.author Llorens Rodríguez, Roberto es_ES
dc.contributor.author Lejeune, Nicolas es_ES
dc.contributor.author Veeramuthu, Vigneswaran es_ES
dc.contributor.author De Marco, Sabrina es_ES
dc.contributor.author Demertzi, Athena es_ES
dc.contributor.author Duclos, Catherine es_ES
dc.contributor.author Morrissey, Ann-Marie es_ES
dc.contributor.author Chatelle, Camille es_ES
dc.contributor.author Estraneo, Anna es_ES
dc.date.accessioned 2021-04-22T03:31:27Z
dc.date.available 2021-04-22T03:31:27Z
dc.date.issued 2020-12 es_ES
dc.identifier.uri http://hdl.handle.net/10251/165481
dc.description.abstract [EN] Covert cognition in patients with disorders of consciousness represents a real diagnostic conundrum for clinicians. In this meta-analysis, our main objective was to identify clinical and demographic variables that are more likely to be associated with responding to an active paradigm. Among 2018 citations found on PubMed, 60 observational studies were found relevant. Based on the QUADAS-2, 49 studies were considered. Data from 25 publications were extracted and included in the meta-analysis. Most of these studies used electrophysiology as well as counting tasks or mental imagery. According to our statistical analysis, patients clinically diagnosed as being in a vegetative state and in a minimally conscious state minus (MCS-) show similar likelihood in responding to active paradigm and responders are most likely suffering from a traumatic brain injury. In the future, multi-centric studies should be performed in order to increase sample size, with similar methodologies and include structural and functional neuroimaging in order to identify cerebral markers related to such a challenging diagnosis. es_ES
dc.description.sponsorship C.S. would like to thank Felice Loverso, the Casa Colina Board of Directors, the Casa Colina Foundation and the International Brain Injury Association for supporting this research. es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation.ispartof Brain Sciences es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Severe brain injury es_ES
dc.subject Consciousness es_ES
dc.subject Vegetative state es_ES
dc.subject Minimally conscious state es_ES
dc.subject Covert cognition es_ES
dc.subject Cognitive motor dissociation es_ES
dc.subject.classification TEORIA DE LA SEÑAL Y COMUNICACIONES es_ES
dc.title Covert Cognition in Disorders of Consciousness: A Meta-Analysis es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/brainsci10120930 es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Schnakers, C.; Hirsch, M.; Noé, E.; Llorens Rodríguez, R.; Lejeune, N.; Veeramuthu, V.; De Marco, S.... (2020). Covert Cognition in Disorders of Consciousness: A Meta-Analysis. Brain Sciences. 10(12):1-11. https://doi.org/10.3390/brainsci10120930 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/brainsci10120930 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 11 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 10 es_ES
dc.description.issue 12 es_ES
dc.identifier.eissn 2076-3425 es_ES
dc.identifier.pmid 33276451 es_ES
dc.identifier.pmcid PMC7759773 es_ES
dc.relation.pasarela S\425046 es_ES
dc.contributor.funder Casa Colina Foundation es_ES
dc.contributor.funder International Brain Injury Association es_ES
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