- -

When, How, and to What Extent Are Individuals with Unresponsive Wakefulness Syndrome Able to Progress? Functional Independence

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

When, How, and to What Extent Are Individuals with Unresponsive Wakefulness Syndrome Able to Progress? Functional Independence

Show simple item record

Files in this item

dc.contributor.author Olaya, José es_ES
dc.contributor.author Noé, Enrique es_ES
dc.contributor.author Navarro, María Dolores es_ES
dc.contributor.author O'Valle, Myrtha es_ES
dc.contributor.author Colomer, Carolina es_ES
dc.contributor.author Moliner, Belén es_ES
dc.contributor.author Ippoliti, Camilla es_ES
dc.contributor.author Ferri, Joan es_ES
dc.contributor.author Maza, Anny es_ES
dc.contributor.author Llorens Rodríguez, Roberto es_ES
dc.date.accessioned 2021-04-24T03:30:59Z
dc.date.available 2021-04-24T03:30:59Z
dc.date.issued 2020-12 es_ES
dc.identifier.uri http://hdl.handle.net/10251/165555
dc.description.abstract [EN] Accurate estimation of the functional independence of patients with unresponsive wakefulness syndrome (UWS) is essential to adjust family and clinical expectations and plan long-term necessary resources. Although different studies have described the clinical course of these patients, they have methodological limitations that could restrict generalization of the results. This study investigates the neurobehavioral progress of 100 patients with UWS consecutively admitted to a neurorehabilitation center using systematic weekly assessments based on standardized measures, and the functional independence staging of those patients who emerged from a minimally conscious state (MCS) during the first year post-emergence. Our results showed that one year after emergence, most patients were severely dependent, although some of them showed extreme or moderate severity. Clinically meaningful functional improvement was less likely to occur in cognitively-demanding activities, such as activities of daily living and executive function. Consequently, the use of specific and staging functional independence measures, with domain-specific evaluations, are recommended to detect the functional changes that might be expected in these patients. The information provided by these instruments, together with that obtained from repeated assessments of the preserved consciousness with standardized instruments, could help clinicians to adjust expectations and plan necessary resources for this population. es_ES
dc.description.sponsorship This research was funded by the program RISE-Marie-Slodowska-Curie of the European Commission (Grant agreement 778234), by Conselleria de Educacion, Investigacion, Cultura y Deporte of Generalitat Valenciana (SEJI/2019/017), and by Vicerrectorado de Investigacion, Innovacion y transferencia of Universitat Politecnica de Valencia (PAID-06-18). es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation UPV/PAID-06-18 es_ES
dc.relation GENERALITAT VALENCIANA/SEJI/2019/017 es_ES
dc.relation.ispartof Brain Sciences es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Unresponsive wakefulness syndrome es_ES
dc.subject Vegetative state es_ES
dc.subject Minimally conscious state es_ES
dc.subject Disorders of consciousness es_ES
dc.subject Brain damage es_ES
dc.subject Disability es_ES
dc.subject Independence es_ES
dc.subject Functionality es_ES
dc.subject.classification TEORIA DE LA SEÑAL Y COMUNICACIONES es_ES
dc.title When, How, and to What Extent Are Individuals with Unresponsive Wakefulness Syndrome Able to Progress? Functional Independence es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/brainsci10120990 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/778234/EU/Disorders of Consciousness (DoC): enhancing the transfer of knowledge and professional skills on evidence-based interventions and validated technology for a better management of patients/ es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Olaya, J.; Noé, E.; Navarro, MD.; O'valle, M.; Colomer, C.; Moliner, B.; Ippoliti, C.... (2020). When, How, and to What Extent Are Individuals with Unresponsive Wakefulness Syndrome Able to Progress? Functional Independence. Brain Sciences. 10(12):1-14. https://doi.org/10.3390/brainsci10120990 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/brainsci10120990 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 14 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 10 es_ES
dc.description.issue 12 es_ES
dc.identifier.eissn 2076-3425 es_ES
dc.identifier.pmid 33339138 es_ES
dc.identifier.pmcid PMC7765669 es_ES
dc.relation.pasarela S\425047 es_ES
dc.contributor.funder European Commission es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder Universitat Politècnica de València es_ES


This item appears in the following Collection(s)

Show simple item record