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dc.contributor.author | Marcos-Garces, Victor | es_ES |
dc.contributor.author | Gavara-Doñate, Josep | es_ES |
dc.contributor.author | Monmeneu-Menadas, Jose Vicente | es_ES |
dc.contributor.author | Lopez-Lereu, Maria P. | es_ES |
dc.contributor.author | Pérez, Nerea | es_ES |
dc.contributor.author | Rios-Navarro, César | es_ES |
dc.contributor.author | De Dios, Elena | es_ES |
dc.contributor.author | Moratal, David | es_ES |
dc.contributor.author | Miñana, Gema | es_ES |
dc.contributor.author | Núñez, Julio | es_ES |
dc.contributor.author | Chorro Gasco, Francisco J. | es_ES |
dc.contributor.author | Bodi, V. | es_ES |
dc.date.accessioned | 2021-05-25T03:33:19Z | |
dc.date.available | 2021-05-25T03:33:19Z | |
dc.date.issued | 2020-06 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/166760 | |
dc.description.abstract | [EN] Vasodilator stress cardiac magnetic resonance (stressCMR) has shown robust diagnostic and prognostic value in patients with known or suspected chronic coronary syndrome (CCS). However, it is unknown whether integration of stressCMR with clinical variables in a simple clinical-imaging score can straightforwardly predict all-cause mortality in this population. We included 6187 patients in a large registry that underwent stressCMR for known or suspected CCS. Several clinical and stressCMR variables were collected, such as left ventricular ejection fraction (LVEF) and ischemic burden (number of segments with stress-induced perfusion defects (PD)). During a median follow-up of 5.56 years, we registered 682 (11%) all-cause deaths. The only independent predictors of all-cause mortality in multivariable analysis were age, male sex, diabetes mellitus (DM), LVEF and ischemic burden. Based on the weight of the chi-square increase at each step of the multivariable analysis, we created a simple clinical-stressCMR (C-CMR-10) score that included these variables (age >= 65 years = 3 points, LVEF <= 50% = 3 points, DM = 2 points, male sex = 1 point, and ischemic burden > 5 segments = 1 point). This 0 to 10 points C-CMR-10 score showed good performance to predict all-cause annualized mortality rate ranging from 0.29%/year (score = 0) to >4.6%/year (score >= 7). The goodness of the model and of the C-CMR-10 score was separately confirmed in 2 internal cohorts (n> 3000 each). We conclude that a novel and simple clinical-stressCMR score, which includes clinical and stressCMR variables, can provide robust prediction of the risk of long-term all-cause mortality in a population of patients with known or suspected CCS. | es_ES |
dc.description.sponsorship | This work was supported by the Instituto de Salud Carlos III and co-funded by Fondo Europeo de Desarrollo Regional (FEDER) (grant numbers PI17/01836 and CIBERCV16/11/00486). | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | MDPI AG | es_ES |
dc.relation.ispartof | Journal of Clinical Medicine | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject | Cardiac magnetic resonance | es_ES |
dc.subject | Chronic coronary syndrome | es_ES |
dc.subject | Ischemic burden | es_ES |
dc.subject | Prognosis | es_ES |
dc.subject | Score | es_ES |
dc.subject | All-Cause mortality | es_ES |
dc.subject.classification | TECNOLOGIA ELECTRONICA | es_ES |
dc.title | A Novel Clinical and Stress Cardiac Magnetic Resonance (C-CMR-10) Score to Predict Long-Term All-Cause Mortality in Patients with Known or Suspected Chronic Coronary Syndrome | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.3390/jcm9061957 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ISCIII//PI17%2F01836/ES/Estudio multidisciplinar de la obstrucción microvascular y su reparación tras un infarto agudo demiocardio: de la arteria coronaria a la microcirculación. Foco en el factor VEGF-A165b/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00486/ES/ENFERMEDADES CARDIOVASCULARES/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica | es_ES |
dc.description.bibliographicCitation | Marcos-Garces, V.; Gavara-Doñate, J.; Monmeneu-Menadas, JV.; Lopez-Lereu, MP.; Pérez, N.; Rios-Navarro, C.; De Dios, E.... (2020). A Novel Clinical and Stress Cardiac Magnetic Resonance (C-CMR-10) Score to Predict Long-Term All-Cause Mortality in Patients with Known or Suspected Chronic Coronary Syndrome. Journal of Clinical Medicine. 9(6):1-13. https://doi.org/10.3390/jcm9061957 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/jcm9061957 | es_ES |
dc.description.upvformatpinicio | 1 | es_ES |
dc.description.upvformatpfin | 13 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 9 | es_ES |
dc.description.issue | 6 | es_ES |
dc.identifier.eissn | 2077-0383 | es_ES |
dc.identifier.pmid | 32585832 | es_ES |
dc.identifier.pmcid | PMC7356983 | es_ES |
dc.relation.pasarela | S\427159 | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | European Regional Development Fund | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad | es_ES |
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dc.subject.ods | 03.- Garantizar una vida saludable y promover el bienestar para todos y todas en todas las edades | es_ES |