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dc.contributor.author | LOZANO JUSTE, JORGE | es_ES |
dc.contributor.author | García-Maquilón, Irene | es_ES |
dc.contributor.author | Ruiz-Partida, Rafael | es_ES |
dc.contributor.author | Rodríguez Egea, Pedro Luís | es_ES |
dc.date.accessioned | 2021-11-05T12:57:35Z | |
dc.date.available | 2021-11-05T12:57:35Z | |
dc.date.issued | 2020-09 | es_ES |
dc.identifier.issn | 1360-1385 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/176167 | |
dc.description.abstract | [EN] Following virtual screening and structure-based ligand optimization, researchers have developed opabactin (OP), an abscisic acid (ABA)-receptor agonist with tenfold greater in vivo activity than ABA. This new ligand surpasses previous agonists for its potency and bioactivity on staple crops. OP leads a new class of agrochemicals designed to protect crops from drought. | es_ES |
dc.description.sponsorship | We thank Laetitia Poidevin (IBMCP-UPV-CSIC) and Jessica Toth (UCR) for comments on the manuscript. The editor and four anonymous reviewers are also acknowledged for their constructive suggestions. We apologize to authors whose work could not be cited due to space limitations. We also acknowledge Universidad Politecnica de Valencia for the grant SP20180340 (PAID-06-18) to J.L-J. and Ministerio de Ciencia, Innovacion y Universidades for the grant RTC-2017-6019-2 to P.L.R. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Trends in Plant Science | es_ES |
dc.rights | Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) | es_ES |
dc.subject | Abiotic stress | es_ES |
dc.subject | Abscisic acid | es_ES |
dc.subject | Drug discovery | es_ES |
dc.subject | ABA-receptor agonist | es_ES |
dc.subject.classification | BIOQUIMICA Y BIOLOGIA MOLECULAR | es_ES |
dc.title | Drug Discovery for Thirsty Crops | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.tplants.2020.07.001 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/Ministerio de Ciencia, Innovación y Universidades//RTC-2017-6019-2//Descubrimiento de agroquímicos para mejorar la resistencia a la sequía de plantas de cosecha. / | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/UPV-VIN//SP20180340//Descubrimiento de agroquímicos para mejorar la resistencia a la sequia de plantas de cosecha./ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes | es_ES |
dc.description.bibliographicCitation | Lozano Juste, J.; García-Maquilón, I.; Ruiz-Partida, R.; Rodríguez Egea, PL. (2020). Drug Discovery for Thirsty Crops. Trends in Plant Science. 25(9):844-846. https://doi.org/10.1016/j.tplants.2020.07.001 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.tplants.2020.07.001 | es_ES |
dc.description.upvformatpinicio | 844 | es_ES |
dc.description.upvformatpfin | 846 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 25 | es_ES |
dc.description.issue | 9 | es_ES |
dc.identifier.pmid | 32690361 | es_ES |
dc.relation.pasarela | S\426004 | es_ES |
dc.contributor.funder | UNIVERSIDAD POLITECNICA DE VALENCIA | es_ES |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades | es_ES |