- -

Roles of host genetics and sperm microbiota in reproductive success in healthy rabbit

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

  • Estadisticas de Uso

Roles of host genetics and sperm microbiota in reproductive success in healthy rabbit

Show simple item record

Files in this item

dc.contributor.author Marco-Jiménez, Francisco es_ES
dc.contributor.author Borrás-Pérez, Sara es_ES
dc.contributor.author Garcia-Dominguez, X es_ES
dc.contributor.author D Auria, Giuseppe es_ES
dc.contributor.author Vicente Antón, José Salvador es_ES
dc.contributor.author Marin, Clara es_ES
dc.date.accessioned 2021-11-05T14:08:05Z
dc.date.available 2021-11-05T14:08:05Z
dc.date.issued 2020-12 es_ES
dc.identifier.issn 0093-691X es_ES
dc.identifier.uri http://hdl.handle.net/10251/176314
dc.description.abstract [EN] Although the effects of sperm microbiota and sperm quality have been described previously, recent studies provide evidence that female genital modifications triggered by seminal components could be of significant importance to identify some disturbances associated with fertility. So, sperm microbiota could play a key role in sperm quality, contributing to fertilisation. To understand how sperm microbiota diversity is influenced by the host genetics, the symbiotic bacteria in four inbred lines raised in the same animal facility and their effects on sperm quality and fertility were analysed. Forty healthy rabbits from four selected Spanish commercial lines were used in this research (three based on litter performance, designated A, V and LP, and one selected for daily body weight gain, called R). Significant variations in the seminal concentration, morphology and some motion parameters were found among inbred lines, but sperm motility and viability were similar among inbred lines. After mating, inbred lines selected for litter size had the same fertility rate, significantly higher than inbred line selected for body weight (82 ± 3.3%, 79 ± 3.5% and 89 ± 4.5% versus 61 ± 3.7%, for the A, V and LP vs R lines, respectively, p < 0.05). Bacteria belonging to Proteobacteria, Firmicutes, Fusobacteria and Bacteroidetes were identified in sperm microbiota. At genus level, the bacterial community composition in the sperm microbiota was influenced by host genetics. A total of 35, 16, 34, and 51 genera were accurately detected in the A, V, LP, and R lines, respectively. Moreover, Enhydrobacter, Ferruginibacter, Myroides Paracoccus, Rheinheimera, Tepidiphilus, Tetradesmus obliquus and Thauera genera were present only in the inbred lines selected for litter size. Moreover, the discriminant analysis revealed Lysinibacillus and Flavobacterium genera as potential biomarkers for fertility. Thus, these two genera may play a key role in fertility. Our results demonstrated the existence of a rabbit inbred line-specific variation in bacterial occurrence in sperm microbiota. Moreover, fertility differentials among inbred lines that were not predicted by routine semen analysis could be partly explained by the symbiotic state of the semen microbiota. es_ES
dc.description.sponsorship Funding from the Ministry of Economy, Industry and Competitiveness (Research project: AGL2017-85162-C2-1-R) is acknowledged. X.G.D. was supported by a research grant from the Ministry of Economy, Industry and Competitiveness (BES-2015-072429). English text version was revised by N. Macowan English Language Service. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Theriogenology es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject Microbiota es_ES
dc.subject 16S rRNA es_ES
dc.subject Semen es_ES
dc.subject Fertility es_ES
dc.subject Inbred line es_ES
dc.subject.classification BIOLOGIA ANIMAL es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.title Roles of host genetics and sperm microbiota in reproductive success in healthy rabbit es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.theriogenology.2020.09.028 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2017-85162-C2-1-R/ES/MEJORA GENETICA DEL CONEJO DE CARNE: ESTRATEGIAS PARA INCREMENTAR LA EFICACIA DE LA MEJORA, REPRODUCCION Y SALUD DE LINEAS PATERNALES/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural es_ES
dc.description.bibliographicCitation Marco-Jiménez, F.; Borrás-Pérez, S.; Garcia-Dominguez, X.; D Auria, G.; Vicente Antón, JS.; Marin, C. (2020). Roles of host genetics and sperm microbiota in reproductive success in healthy rabbit. Theriogenology. 158:416-423. https://doi.org/10.1016/j.theriogenology.2020.09.028 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.theriogenology.2020.09.028 es_ES
dc.description.upvformatpinicio 416 es_ES
dc.description.upvformatpfin 423 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 158 es_ES
dc.identifier.pmid 33039925 es_ES
dc.relation.pasarela S\445381 es_ES
dc.contributor.funder AGENCIA ESTATAL DE INVESTIGACION es_ES


This item appears in the following Collection(s)

Show simple item record