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dc.contributor.author | Collantes-Pablo, Cynthia | es_ES |
dc.contributor.author | González-Pedro, Victoria | es_ES |
dc.contributor.author | Bañuls Polo, María-José | es_ES |
dc.contributor.author | Maquieira Catala, Angel | es_ES |
dc.date.accessioned | 2021-11-05T14:09:04Z | |
dc.date.available | 2021-11-05T14:09:04Z | |
dc.date.issued | 2021-02-26 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/176356 | |
dc.description.abstract | [EN] Despite the rising advances in the field of metal halide perovskite nanocrystals (NCs), the exploitation of such nanoparticles as luminescent labels for ex vivo imaging and biosensing is still unclear and in the early stages of investigation. One of the major challenges toward the implementation of metal halide perovskite NCs in biosensing applications is to produce monodispersed nanoparticles with desired surface characteristics and compatible with aqueous environments. Here, we report the synthesis of monodispersed spherical CsPb2Br5@SiO2 core-shell nanoparticles by post-synthetic chemical transformation of 3D CsPbBr3 NCs in the presence of tetraethyl orthosilicate and a critical water/ammonia ratio. This method involves an ammoniamediated and ammonia-induced "top-down" transformation of as-synthesized 3D CsPbBr3 NCs to smaller CsPb2Br5 nanoclusters (ca. 2-3 nm), which trigger a seed-mediated silica growth, yielding monodispersed spherical blue luminescent (lambda(emission) = 432 nm) CsPb2Br5@SiO2 perovskite nanoparticles. By adjusting the reaction conditions, core-shell nanoparticles of a 36.1 +/- 4.5 nm diameter, which preserve their optical properties in water, were obtained. Besides that, the viability of the developed nanoparticles as a luminescent label for biosensing has been proven by specific biorecognition of the IgG protein in a direct immunoassay. Our work sheds light on the chemical processes and transformations involved in the silica nucleation mechanism in the presence of perovskite nanoparticles and opens the way for the future rational design of the next generation of semiconductor NC luminescent biological labels | es_ES |
dc.description.sponsorship | This work was financially supported by the E.U FEDER projects BiHolog CTQ2016-75749-R and ADBIHOL (PID2019110713RB-I00) from MINECO and PROMETEO/2020/094 from Generalitat Valenciana. C.C. thanks the Spanish Ministry of Economy and Competitiveness for her predoctoral contract (FPI/17 Scholarship). V.G-P. thanks Universitat Polite`cnica de Vale`ncia for her postdoctoral fellowship (Grant-PAID-10-14) and for financial support from the project PAID/16/18 (VIITUPV) | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | American Chemical Society | es_ES |
dc.relation.ispartof | ACS Applied Nano Materials | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject | Cesium lead bromide nanocrystals | es_ES |
dc.subject | Silica growth | es_ES |
dc.subject | CsPb2Br5@SiO2 core-shell nanoparticles | es_ES |
dc.subject | Monodisperse | es_ES |
dc.subject | Stability | es_ES |
dc.subject | Luminescent label | es_ES |
dc.subject | Protein detection | es_ES |
dc.subject.classification | QUIMICA ANALITICA | es_ES |
dc.title | Monodispersed CsPb2Br5@SiO2 Core-Shell Nanoparticles as Luminescent Labels for Biosensing | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1021/acsanm.0c03340 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-110713RB-I00/ES/HACIA EL BIOSENSADO HOLOGRAFICO AVANZADO/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/UPV//PAID%2F16%2F18/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//FPI%2F17/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/UPV//PAID-10-14/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/AEI//CTQ2016-75749-R//BIOSENSORES HOLOGRAFICOS. PRUEBA DE CONCEPTO Y DEMOSTRACION EN APLICACIONES CLINICAS/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GENERALITAT VALENCIANA//PROMETEO%2F2020%2F094//HOLOGRAFÍA. UNA VIA PARA AFRONTAR NUEVOS RETOS EN BIOSENSADO/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.date.embargoEndDate | 2022-02-26 | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Química - Departament de Química | es_ES |
dc.description.bibliographicCitation | Collantes-Pablo, C.; González-Pedro, V.; Bañuls Polo, M.; Maquieira Catala, A. (2021). Monodispersed CsPb2Br5@SiO2 Core-Shell Nanoparticles as Luminescent Labels for Biosensing. ACS Applied Nano Materials. 4(2):2011-2018. https://doi.org/10.1021/acsanm.0c03340 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1021/acsanm.0c03340 | es_ES |
dc.description.upvformatpinicio | 2011 | es_ES |
dc.description.upvformatpfin | 2018 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 4 | es_ES |
dc.description.issue | 2 | es_ES |
dc.identifier.eissn | 2574-0970 | es_ES |
dc.relation.pasarela | S\428988 | es_ES |
dc.contributor.funder | GENERALITAT VALENCIANA | es_ES |
dc.contributor.funder | AGENCIA ESTATAL DE INVESTIGACION | es_ES |
dc.contributor.funder | Universitat Politècnica de València | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad | es_ES |