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dc.contributor.author | Vergara, Marina | es_ES |
dc.contributor.author | Rezaei, Ahmadreza | es_ES |
dc.contributor.author | Schramm, Georg | es_ES |
dc.contributor.author | Rodríguez-Álvarez, María José | es_ES |
dc.contributor.author | Benlloch Baviera, Jose María | es_ES |
dc.contributor.author | Nuyts, Johan | es_ES |
dc.date.accessioned | 2022-01-27T19:03:09Z | |
dc.date.available | 2022-01-27T19:03:09Z | |
dc.date.issued | 2021-09 | es_ES |
dc.identifier.issn | 2469-7311 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/180288 | |
dc.description.abstract | [EN] Several research groups are studying organ-dedicated limited angle positron emission tomography (PET) systems to optimize performance-cost ratio, sensitivity, access to the patient, and/or flexibility. Often open systems are considered, typically consisting of two detector panels of various sizes. Such systems provide incomplete sampling due to limited angular coverage and/or truncation, which leads to artifacts in the reconstructed activity images. In addition, these organ-dedicated PET systems are usually stand-alone systems, and as a result, no attenuation information can be obtained from anatomical images acquired in the same imaging session. It has been shown that the use of time-of-flight (TOF) information reduces incomplete data artifacts and enables the joint estimation of the activity and the attenuation factors. In this work, we explore with simple 2-D simulations the performance and stability of a joint reconstruction algorithm, for imaging with a limited angle PET system. The reconstruction is based on the so-called maximum-likelihood attenuation correction factors (MLACF) algorithm and uses linear attenuation coefficients in a known-tissue-class region to obtain absolute quantification. Different panel sizes and different TOF resolutions are considered. The noise propagation is compared to that of MLEM reconstruction with exact attenuation correction (AC) for the same PET system. The results show that with good TOF resolution, images of good visual quality can be obtained. If also a good scatter correction can be implemented, quantitative PET imaging will be possible. Further research, in particular on scatter correction, is required. | es_ES |
dc.description.sponsorship | This work was supported in part by the European Research Council (ERC) through the European Unions Horizon 2020 Research and Innovation Program under Grant 695536; in part by the Research Foundation Flanders (FWO) under Project 12T7118N and Project G062220N; and in part by the NIH Project under Grant 1P41EB017183-01A1. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Institute of Electrical and Electronics Engineers | es_ES |
dc.relation.ispartof | IEEE Transactions on Radiation and Plasma Medical Sciences | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Time-of-Flight | es_ES |
dc.subject | Limited angle | es_ES |
dc.subject | Sinogram truncation | es_ES |
dc.subject | Dedicated systems | es_ES |
dc.subject | PET imaging | es_ES |
dc.subject | Interior problem | es_ES |
dc.subject.classification | MATEMATICA APLICADA | es_ES |
dc.title | 2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1109/TRPMS.2021.3079462 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/H2020/695536/EU/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-107790RB-C22/ES/DESARROLLO DEL SOFTWARE PARA UN SISTEMA PET DE CRISTAL CONTINUO APLICADO AL CANCER DE MAMA/ | |
dc.relation.projectID | info:eu-repo/grantAgreement/FWO//G062220N/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//TEC2016-79884-C2-2-R/ES/DESARROLLO DEL SOFTWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE STRESS/ | |
dc.relation.projectID | info:eu-repo/grantAgreement/NIH//1P41EB017183-01A1/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FWO//12T7118N/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Matemática Aplicada - Departament de Matemàtica Aplicada | es_ES |
dc.description.bibliographicCitation | Vergara, M.; Rezaei, A.; Schramm, G.; Rodríguez-Álvarez, MJ.; Benlloch Baviera, JM.; Nuyts, J. (2021). 2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET. IEEE Transactions on Radiation and Plasma Medical Sciences. 5(5):712-722. https://doi.org/10.1109/TRPMS.2021.3079462 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1109/TRPMS.2021.3079462 | es_ES |
dc.description.upvformatpinicio | 712 | es_ES |
dc.description.upvformatpfin | 722 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 5 | es_ES |
dc.description.issue | 5 | es_ES |
dc.identifier.pmid | 34541435 | es_ES |
dc.identifier.pmcid | PMC8445242 | es_ES |
dc.relation.pasarela | S\439318 | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.contributor.funder | Research Foundation Flanders | es_ES |
dc.contributor.funder | National Institutes of Health, EEUU | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad | |
dc.contributor.funder | Agencia Estatal de Investigación |