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A Fast 0.5 T Prepolarizer Module for Preclinical Magnetic Resonance Imaging

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A Fast 0.5 T Prepolarizer Module for Preclinical Magnetic Resonance Imaging

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dc.contributor.author Rigla, J. P. es_ES
dc.contributor.author Borreguero-Morata, José es_ES
dc.contributor.author Gramage, Carlos es_ES
dc.contributor.author Pallás-Lodeiro, Eduardo es_ES
dc.contributor.author González-Hernández, José Manuel es_ES
dc.contributor.author Bosch-Esteve, Rubén es_ES
dc.contributor.author Algarín-Guisado, José Miguel es_ES
dc.contributor.author Sanchez-Andres, Juan V. es_ES
dc.contributor.author Galve, Fernando es_ES
dc.contributor.author Grau-Ruiz, Daniel es_ES
dc.contributor.author Pellicer, Rubén es_ES
dc.contributor.author Rios, Alfonso es_ES
dc.contributor.author Benlloch Baviera, Jose María es_ES
dc.contributor.author Alonso, Joseba es_ES
dc.date.accessioned 2022-01-28T07:41:29Z
dc.date.available 2022-01-28T07:41:29Z
dc.date.issued 2022-02 es_ES
dc.identifier.issn 0018-9464 es_ES
dc.identifier.uri http://hdl.handle.net/10251/180339
dc.description.abstract [EN] We present a magnet and high power electronics for Prepolarized Magnetic Resonance Imaging (PMRI) in a home-made, special-purpose preclinical system designed for simultaneous visualization of hard and soft biological tissues. The sensitivity of MRI systems grows with field strength, but so do their costs. PMRI can boost the signal-to-noise ratio (SNR) in affordable low-field scanners by means of a long and strong magnetic pulse. However, this must be rapidly switched off prior to the imaging pulse sequence, in timescales shorter than the spin relaxation (or T1) time of the sample. We have operated our prepolarizer at up to 0.5 T and demonstrated enhanced magnetization, image SNR and tissue contrast with PMRI of tap water, an ex vivo mouse brain and food samples. These have T1 times ranging from hundreds of milli-seconds to single seconds, while the preliminary high-power electronics setup employed in this work can switch off the prepolarization field in tens of milli-seconds. In order to make this system suitable for solid-state matter and hard tissues, which feature T1 times as short as 10 ms, we are developing new electronics which can cut switching times to ~ 300 ¿s. This does not require changes in the prepolarizer module, opening the door to the first experimental demonstration of PMRI on hard biological tissues. es_ES
dc.description.sponsorship This work was supported in part by the European Commission under Grant 737180 (FET-Open: HistoMRI), in part by the Ministerio de Ciencia e Innovación of Spain for Research under Grant PID2019-111436RB-C21, and in part by the European Union through the Programa Operativo del Fondo Europeo de Desarrollo Regional (FEDER) of the Comunitat Valenciana 2014¿2020 under Grant IDIFEDER/2018/022. The work of José M. González was supported by the Innodocto Program of the Agencia Valenciana de la Innovación under Grant INNTA3/2020/22. The work of Juan V. Sanchez-Andres was supported by the Universitat Jaume I - Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (UJISABIO) under Grant 21I044.01/1 es_ES
dc.language Inglés es_ES
dc.publisher Institute of Electrical and Electronics Engineers es_ES
dc.relation.ispartof IEEE Transactions on Magnetics es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject MRI es_ES
dc.subject Low field es_ES
dc.subject Prepolarization es_ES
dc.subject Magnet design es_ES
dc.subject Electromagnet es_ES
dc.title A Fast 0.5 T Prepolarizer Module for Preclinical Magnetic Resonance Imaging es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1109/TMAG.2021.3080840 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-111436RB-C21/ES/IMAGEN FOTOACUSTICA CON NANOPARTICUTLAS CON PROPIEDADES OPTOELECTRONICAS Y MAGNETICAS/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AVI//INNTA3%2F2020%2F22/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/737180/EU/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/UJI//21I044.01%2F1/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EDUC.INVEST.CULT.DEP//IDIFEDER%2F2018%2F022//EQUIPOS PARA TECNICAS MIXTAS ELECTROMAGNETICAS-ULTRASONICAS PARA IMAGEN MEDICA/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular es_ES
dc.description.bibliographicCitation Rigla, JP.; Borreguero-Morata, J.; Gramage, C.; Pallás-Lodeiro, E.; González-Hernández, JM.; Bosch-Esteve, R.; Algarín-Guisado, JM.... (2022). A Fast 0.5 T Prepolarizer Module for Preclinical Magnetic Resonance Imaging. IEEE Transactions on Magnetics. 58(2):1-8. https://doi.org/10.1109/TMAG.2021.3080840 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1109/TMAG.2021.3080840 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 8 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 58 es_ES
dc.description.issue 2 es_ES
dc.relation.pasarela S\451120 es_ES
dc.contributor.funder Universitat Jaume I es_ES
dc.contributor.funder GENERALITAT VALENCIANA es_ES
dc.contributor.funder Agencia Estatal de Investigación es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Agència Valenciana de la Innovació es_ES
dc.contributor.funder European Union s Horizon 2020 research and innovation programme es_ES


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