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Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach

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Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach

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Dasí, A.; Hernández-Romero, I.; Gómez, JF.; Climent, AM.; Ferrero De Loma-Osorio, JM.; Trenor Gomis, BA. (2021). Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach. Computers in Biology and Medicine. 137:1-10. https://doi.org/10.1016/j.compbiomed.2021.104796

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Title: Analysis of the response of human iPSC-derived cardiomyocyte tissue to I CaL block. A combined in vitro and in silico approach
Author: Dasí, Albert Hernández-Romero, Ismael Gómez, Juan F. Climent, Andreu M. Ferrero De Loma-Osorio, José María Trenor Gomis, Beatriz Ana
UPV Unit: Universitat Politècnica de València. Centro de Investigación e Innovación en Bioingeniería - Centre de Recerca i Innovació en Bioenginyeria
Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Issued date:
Abstract:
[EN] The high incidence of cardiac arrythmias underlines the need for the assessment of pharmacological therapies. In this field of drug efficacy, as in the field of drug safety highlighted by the Comprehensive in Vitro ...[+]
Subjects: HiPSC-CM , HAdultV-CM , Re-entry , ICaL block
Copyrigths: Reconocimiento (by)
Source:
Computers in Biology and Medicine. (issn: 0010-4825 )
DOI: 10.1016/j.compbiomed.2021.104796
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.compbiomed.2021.104796
Project ID:
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-104356RB-C41/ES/MODELO MULTIESCALA DE PATOLOGIAS CARDIACAS Y OPTIMIZACION DE TERAPIAS PERSONALIZADAS/
info:eu-repo/grantAgreement/EC/H2020/101016496/EU
info:eu-repo/grantAgreement/MCIU//RYC2018-024346B-750/
info:eu-repo/grantAgreement/GENERALITAT VALENCIANA//PROMETEO%2F2020%2F043//MODELOS IN-SILICO MULTI-FISICOS Y MULTI-ESCALA DEL CORAZON PARA EL DESARROLLO DE NUEVOS METODOS DE PREVENCION, DIAGNOSTICO Y TRATAMIENTO EN MEDICINA PERSONALIZADA (HEART IN-SILICO MODELS)/
info:eu-repo/grantAgreement/AEI//PRE2020-091849//MODELO MULTIESCALA DE PATOLOGIAS CARDIACAS Y OPTIMIZACION DE TERAPIAS PERSONALIZADAS/
Thanks:
This work was supported by the "Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2017-2020" of the Ministerio de Ciencia e Innovacion y Universidades (PID2019-104356RB-C41/AEI/10.13039/501100011033) , ...[+]
Type: Artículo

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