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Multi-omic data integration study of immune system alterations in the development of minimal hepatic encephalopathy in patients with liver cirrhosis

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Multi-omic data integration study of immune system alterations in the development of minimal hepatic encephalopathy in patients with liver cirrhosis

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Rubio Martínez-Abarca, MT. (2022). Multi-omic data integration study of immune system alterations in the development of minimal hepatic encephalopathy in patients with liver cirrhosis [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/185116

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Title: Multi-omic data integration study of immune system alterations in the development of minimal hepatic encephalopathy in patients with liver cirrhosis
Author: Rubio Martínez-Abarca, María Teresa
Director(s): Conesa Cegarra, Ana Felipo Orts, Vicente Tarazona Campos, Sonia
UPV Unit: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Read date / Event date:
2022-06-30
Issued date:
Abstract:
[ES] El objetivo principal de este trabajo fue conocer las alteraciones inmunológicas asociadas a la inflamación periférica que desencadenan deterioro cognitivo en los pacientes cirróticos encefalopatía hepática mínima ...[+]


[CA] L'objectiu principal d'aquest treball va ser conèixer les alteracions immunològiques associades a la inflamació perifèrica que desencadenen deteriorament cognitiu en els pacients cirròtics amb encefalopatia hepàtica ...[+]


[EN] The main objective of this work was to understand the immunological alterations associated with the peripheral inflammation that trigger minimal hepatic encephalopathy (MHE) in patients with cirrhosis. These changes ...[+]
Subjects: Encefalopatía hepática mínima , Células T CD4 , Análisis multiómico , Transcriptómica , Metabolómica , Mínimos cuadrados , Receptor de células T , Minimal Hepatic Encephalopathy , CD4 T-cells , Multi-omic analysis , Transcriptomics , Metabolomics , RNA-seq , MiRNA-seq , Partial Least Squares , T-cell receptor , Nextflow
Copyrigths: Reserva de todos los derechos
DOI: 10.4995/Thesis/10251/185116
Publisher:
Universitat Politècnica de València
Type: Tesis doctoral

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