Mostrar el registro sencillo del ítem
dc.contributor.author | Pueyo-Périz, E. | es_ES |
dc.contributor.author | Téllez-Marquès, C. | es_ES |
dc.contributor.author | Radosevic, A. | es_ES |
dc.contributor.author | Morató, O. | es_ES |
dc.contributor.author | Visa, L. | es_ES |
dc.contributor.author | Ilzarbe, L. | es_ES |
dc.contributor.author | Berjano, Enrique | es_ES |
dc.contributor.author | de Vicente, E. | es_ES |
dc.contributor.author | Poves, I. | es_ES |
dc.contributor.author | Ielpo, B. | es_ES |
dc.contributor.author | Grande, L. | es_ES |
dc.contributor.author | Burdío, F. | es_ES |
dc.contributor.author | Sánchez-Velázquez, P. | es_ES |
dc.date.accessioned | 2022-11-28T19:01:54Z | |
dc.date.available | 2022-11-28T19:01:54Z | |
dc.date.issued | 2022-05-06 | es_ES |
dc.identifier.issn | 2045-2322 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/190279 | |
dc.description.abstract | [EN] To demonstrate the efficacy of radiofrequency for pancreatic stump closure in reducing the incidence of postoperative pancreatic fistula (POPF) in distal pancreatectomy (DP) compared with mechanical transection methods. Despite all the different techniques of pancreatic stump closure proposed for DP, best practice for avoiding POPF remains an unresolved issue, with an incidence of up to 30% regardless of center volume or surgical expertise. DP was performed in a cohort of patients by applying radiofrequency to stump closure (RF Group) and compared with mechanical closure (Control Group). A propensity score (PS) matched cohort study was carried out to minimize bias from nonrandomized treatment assignment. Cohorts were matched by PS accounting for factors significantly associated with either undergoing RF transection or mechanical closure through logistic regression analysis. The primary end-point was the incidence of clinically relevant POPF (CR-POPF). Of 89 patients included in the whole cohort, 13 case patients from the RF-Group were 1:1 matched to 13 control patients. In both the first independent analysis of unmatched data and subsequent adjustment to the overall propensity score-matched cohort, a higher rate of CR-POPF in the Control Group compared with the RF-Group was detected (25.4% vs 5.3%, p = 0.049 and 53.8% vs 0%; p = 0.016 respectively). The RF Group showed better outcomes in terms of readmission rate (46.2% vs 0%, p = 0.031). No significant differences were observed in terms of mortality, major complications (30.8% vs 0%, p = 0.063) or length of hospital stay (5.7 vs 5.2 days, p = 0.89). Findings suggest that the RF-assisted technique is more efficacious in reducing CR-POPF than mechanical pancreatic stump closure. | es_ES |
dc.description.sponsorship | This work was supported completely by a grant for medical research from the Catalan Surgery Society. Project PI20/00008, funded by Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Nature Publishing Group | es_ES |
dc.relation.ispartof | Scientific Reports | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject.classification | TECNOLOGIA ELECTRONICA | es_ES |
dc.title | Radiofrequency-assisted transection of the pancreas vs stapler in distal pancreatectomy: a propensity score matched cohort analysis | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1038/s41598-022-11583-0 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00008/ES/TRANSECCION PANCREATICA ASISTIDA POR RADIOFRECUENCIA VS ENDOGRAPADORA (ESTUDIO TRANSPAIRE). ENSAYO CLINICO EN FASE III/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería del Diseño - Escola Tècnica Superior d'Enginyeria del Disseny | es_ES |
dc.description.bibliographicCitation | Pueyo-Périz, E.; Téllez-Marquès, C.; Radosevic, A.; Morató, O.; Visa, L.; Ilzarbe, L.; Berjano, E.... (2022). Radiofrequency-assisted transection of the pancreas vs stapler in distal pancreatectomy: a propensity score matched cohort analysis. Scientific Reports. 12(1):1-8. https://doi.org/10.1038/s41598-022-11583-0 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1038/s41598-022-11583-0 | es_ES |
dc.description.upvformatpinicio | 1 | es_ES |
dc.description.upvformatpfin | 8 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 12 | es_ES |
dc.description.issue | 1 | es_ES |
dc.identifier.pmid | 35523857 | es_ES |
dc.identifier.pmcid | PMC9076639 | es_ES |
dc.relation.pasarela | S\465204 | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.description.references | Kleeff, J. et al. Distal pancreatectomy: Risk factors for surgical failure in 302 consecutive cases. Ann. Surg. 245(4), 573–582 (2007). | es_ES |
dc.description.references | De Rooij, T. et al. Minimally invasive versus open distal pancreatectomy (LEOPARD): A multicenter patient-blinded randomized controlled trial. Ann. Surg. 269(1), 2–9 (2019). | es_ES |
dc.description.references | Knaebel, H. P., Diener, M. K., Wente, M. N., Büchler, M. W. & Seiler, C. M. Systematic review and meta-analysis of technique for closure of the pancreatic remnant after distal pancreatectomy. Br. J. Surg. 92(5), 539–546 (2005). | es_ES |
dc.description.references | Rodríguez, J. R. et al. Implications and cost of pancreatic leak following distal pancreatic resection. Arch. Surg. 141(4), 361–366 (2006). | es_ES |
dc.description.references | Diener, M. K. et al. Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): A randomised, controlled multicentre trial. Lancet 377(9776), 1514–1522 (2011). | es_ES |
dc.description.references | Montorsi, M. et al. Efficacy of an absorbable fibrin sealant patch (TachoSil) after distal pancreatectomy: A multicenter, randomized, controlled trial. Ann. Surg. 256(5), 853–860 (2012). | es_ES |
dc.description.references | Suc, B. et al. Temporary fibrin glue occlusion of the main pancreatic duct in the prevention of intra-abdominal complications after pancreatic resection: Prospective randomized trial. Ann. Surg. 237(1), 57–65 (2003). | es_ES |
dc.description.references | Bassi, C. et al. The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after. Surgery 161(3), 584–591 (2017). | es_ES |
dc.description.references | Maggino, L., Malleo, G., Salvia, R., Bassi, C. & Vollmer, C. M. Defining the practice of distal pancreatectomy around the world. HPB 21(10), 1277–1287 (2019). | es_ES |
dc.description.references | McCormack, L., Petrowsky, H. & Clavien, P. A. Novel approach using dissecting sealer for uncinate process resection during pancreaticoduodenectomy. J. Am. Coll. Surg. 202(3), 556–558 (2006). | es_ES |
dc.description.references | Ganguli, S. & Goldberg, S. N. Radiofrequency equipment and scientific basis for radiofrequency ablation. Interv. Radiol. Treat. Liver Tumors https://doi.org/10.1017/CBO9780511575433.011 (2008). | es_ES |
dc.description.references | Zervas, N. T. & Kuwayama, A. Pathological characteristics of experimental thermal lesions. Comparison of induction heating and radiofrequency electrocoagulation. J. Neurosurg. 37(4), 418–422 (1972). | es_ES |
dc.description.references | Goldberg, S. N., Gazelle, G. S., Compton, C. C., Mueller, P. R. & Tanabe, K. K. Treatment of intrahepatic malignancy with radiofrequency ablation: Radiologic–pathologic correlation. Cancer 88(11), 2452–2463 (2000). | es_ES |
dc.description.references | Nagakawa, Y. et al. The VIO soft-coagulation system can prevent pancreatic fistula following pancreatectomy. J. Hepatobiliary Pancreat. Surg. 15(4), 359–365 (2008). | es_ES |
dc.description.references | Blansfield, J. A. et al. Novel method of stump closure for distal pancreatectomy with a 75% reduction in pancreatic fistula rate. J. Gastrointest. Surg. 16(3), 524–528 (2012). | es_ES |
dc.description.references | Fronza, J. S., Bentrem, D. J., Baker, M. S., Talamonti, M. S. & Ujiki, M. B. Laparoscopic distal pancreatectomy using radiofrequency energy. Am. J. Surg. 199(3), 401–404 (2010). | es_ES |
dc.description.references | Dorcaratto, D. et al. Radiofrequency is a secure and effective method for pancreatic transection in laparoscopic distal pancreatectomy: Results of a randomized, controlled trial in an experimental model. Surg. Endosc. 27(10), 3710–3719 (2013). | es_ES |
dc.description.references | Quesada, R. et al. Impact of monopolar radiofrequency coagulation on intraoperative blood loss during liver resection: A prospective randomised controlled trial. Int. J. Hyperth. 33(2), 135–141 (2017). | es_ES |
dc.description.references | Ceppa, E. P. et al. Does pancreatic stump closure method influence distal pancreatectomy outcomes?. J. Gastrointest. Surg. 19(8), 1449–1456 (2015). | es_ES |
dc.description.references | Dorcaratto, D. et al. Laparoscopic distal pancreatectomy: Feasibility study of radiofrequency-assisted transection in a porcine model. J. Laparoendosc. Adv. Surg. Tech. 22(3), 242–248 (2012). | es_ES |
dc.description.references | Burdío, F. et al. Radiofrequency-induced heating versus mechanical stapler for pancreatic stump closure: In vivo comparative study. Int. J. Hyperth. 32(3), 272–280 (2016). | es_ES |
dc.description.references | Dindo, D., Demartines, N. & Clavien, P.-A. Classification of surgical complications. Ann. Surg. 240(2), 205–213 (2004). | es_ES |
dc.description.references | Slankamenac, K., Graf, R., Barkun, J., Puhan, M. A. & Clavien, P. A. The comprehensive complication index: A novel continuous scale to measure surgical morbidity. Ann. Surg. 258(1), 1–7 (2013). | es_ES |
dc.description.references | Lonjon, G., Porcher, R., Ergina, P., Fouet, M. & Boutron, I. Potential pitfalls of reporting and bias in observational studies with propensity score analysis assessing a surgical procedure: A methodological systematic review. Ann. Surg. 265(5), 901–909 (2017). | es_ES |
dc.description.references | Burdo, F. et al. A new single-instrument technique for parenchyma division and hemostasis in liver resection: A clinical feasibility study. Am. J. Surg. 200(6), e75–e80 (2010). | es_ES |
dc.description.references | Jimenez, R. E. & Hawkins, W. G. Emerging strategies to prevent the development of pancreatic fistula after distal pancreatectomy. Surgery (United States) 152(3 Suppl.), S64–S70 (2012). | es_ES |