Mathematical modelling of kidney disease stages in patients diagnosed with diabetes mellitus II

Abstract

[EN] The direct costs associated with diabetes mellitus represent 8% of total healthcare expenditure in Spain, amounting to around 6 billion euros per year [1]. The overall prevalence of diabetes in people over 18 years of age (adjusted for age and sex) is estimated at 13.8% in 2010 [2], with type 2 (T2DM) being the most common type of diabetes, accounting for 85-95% of all diabetes cases in high-income countries [3]. T2DM is associated with multiple diseases such as chronic kidney disease [4], retinopathy, pyelonephritis, heart attack or stroke [5]. It is estimated that 35% of patients with T2DM develop diabetic kidney disease [6]. Treatment of end-stage renal disease requires expensive treatments such as haemodialysis and kidney transplantation. The objective of this study is to evaluate in patients with T2DM the degree of renal damage and the risk of suffering complications according to their socio-demographic, clinical and morbidity characteristics and to obtain the weight of the variables that have most influence.