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dc.contributor.author | CARBONELL, ALBERTO![]() |
es_ES |
dc.date.accessioned | 2023-06-15T18:00:40Z | |
dc.date.available | 2023-06-15T18:00:40Z | |
dc.date.issued | 2022-05 | es_ES |
dc.identifier.issn | 0168-1702 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/194260 | |
dc.description.abstract | [EN] Viroids are small (250-400 nucleotides), single-stranded, circular RNAs without protein-coding capacity that infect a large number of ornamental and crop plant species, causing high economic losses worldwide. Strategies to control viroid diseases have included the use of naturally resistant cultivars in breeding programs, the superinfection exclusion with mild strains, the expression of ribonucleases, sense or antisense (catalytic) RNAs and, more recently, RNA interference (RNAi)-based tools. Here, I review the different RNAi strategies used to control vimid infections in plants, with particular focus on highly specific artificial small RNA (art-sRNA)-based tools such as artificial microRNAs and synthetic trans-acting small interfering RNAs. The advantages and future perspectives of art-sRNA-based RNAi for controlling viroid diseases are discussed. | es_ES |
dc.description.sponsorship | This work was supported by grants from Ministerio de Ciencia, Innovacion y Universidades (MCIU, Spain), Agencia Estatal de Investigacion (AEI, Spain) and Fondo Europeo de Desarrollo Regional (FEDER, European Union) [RTI2018-095118-A-100 and RYC-2017-21648 to A.C.]. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Virus Research | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject | Viroid | es_ES |
dc.subject | Artificial small RNA | es_ES |
dc.subject | RNAi | es_ES |
dc.subject | Artificial microRNA | es_ES |
dc.subject | Syn-tasiRNA | es_ES |
dc.subject | Resistance | es_ES |
dc.title | RNAi tools for controlling viroid diseases | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.virusres.2022.198729 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/Ministerio de Ciencia e Innovación//RTI2018-095118-A-100//Complejos ARGONAUTA1 de Plantas: Identificación de sus Componentes Proteicos y de RNA, y Ajuste Fino del Silenciamiento Mediante su Programación por Pequeños RNAs Artificiales / | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/Ministerio de Ciencia e Innovación//RYC-2017-21648//RNA-based regulation of gene expression and antiviral resistance in plants / | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.description.bibliographicCitation | Carbonell, A. (2022). RNAi tools for controlling viroid diseases. Virus Research. 313:1-6. https://doi.org/10.1016/j.virusres.2022.198729 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.virusres.2022.198729 | es_ES |
dc.description.upvformatpinicio | 1 | es_ES |
dc.description.upvformatpfin | 6 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 313 | es_ES |
dc.identifier.pmid | 35263623 | es_ES |
dc.relation.pasarela | S\469935 | es_ES |
dc.contributor.funder | European Regional Development Fund | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación | es_ES |