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Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant

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Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant

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dc.contributor.author Cano-Velázquez, Mildred S. es_ES
dc.contributor.author Bon Corbín, José es_ES
dc.contributor.author Llamazares, M. es_ES
dc.contributor.author Camacho-López, Santiago es_ES
dc.contributor.author Aguilar, Guillermo es_ES
dc.contributor.author Hernández-Cordero, Juan es_ES
dc.contributor.author Trujillo Guillen, Macarena es_ES
dc.date.accessioned 2023-07-04T18:01:38Z
dc.date.available 2023-07-04T18:01:38Z
dc.date.issued 2022-06 es_ES
dc.identifier.issn 0169-2607 es_ES
dc.identifier.uri http://hdl.handle.net/10251/194673
dc.description.abstract [EN] Background and objective: In the last few years, we have been exploring the use of transparent nanocrystalline yttria-stabilized zirconia (nc-YSZ) ceramics as a biomedical transparent cranial implant, referred as the "Window to the Brain " (WttB). The WttB aims at providing chronical optical access to the brain for diagnostics and therapeutic procedures and it has shown to provide an effective means to obtain enhanced results from optical imaging techniques. The objective of this work is to explore the photothermal effects of the Wttb produced when it is irradiated by a laser source. Methods: We make experimental and computer models. The thermal effects of laser irradiation on the nc-YSZ samples were evaluated upon registering the induced temperature changes by means of thermal imaging. The computer models try to mimic the experimental models using a similar geometry, reproducing the physical situation by a couple thermal-optical problem and adjusting the main parameters from the experimental results. Results: Experimental and computational coincides in results: Temperatures at the bottom surface of the implant does not exceed those which produce thermal damage. The quantitative comparison between experimental and computational models show that differences in results are under a reasonable value of 5% and qualitatively we observe a similar behavior. The results provide optimum values for the thermal optical nc-YSZ parameters considering a linear and exponential relationship with temperature for the absorption coefficient: The thermal conductivity is k = 2.13 W/mmiddotK and the absorption coefficient alpha varies from 426 to 526 m(-1) with the linear relationship, and k = 2.04 W/mmiddotK and alpha is an element of [433,502] m(-1) with the exponential. The reflection coefficient is R = 19% in both cases. Conclusions: The temperatures achieved in the nc-YSZ during the laser irradiation are suitable for biomedical applications. The combination of experimental and computational models contributes to build a clinically oriented model with the thermal-optical parameters values stablished and to determine their influence in results. Specifically, the absorption coefficient of the nc-YSZ samples is the most influent parameter in the obtained temperatures. Moreover, this combination provides a method to evaluate the relevant thermal-optical parameters of nc-YSZ samples obtained with different manufacturing processes. es_ES
dc.description.sponsorship This work was supported by the Spanish Ministerio de Ciencia, Innovacion y Universidades under "Programa Estatal de I + D + I Orientada a los Retos de la Sociedad", Grant No. "RTI2018- 094357-B-C21". The WttB project is being funded by NSF through grants NSF-PIRE 1545852, NSF-EAGER 1547014 and by CONACYT (Mexico) through FORDECyT-PRONACES, Grant 246648. M.S.C.V. acknowledges support from "Beca Mixta, Grant 741249" (CONACYT, Mexico) . es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Computer Methods and Programs in Biomedicine es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject Nanocrystalline yttria stabilized zirconia es_ES
dc.subject Cranial implant es_ES
dc.subject Heat conduction es_ES
dc.subject Window to the brain es_ES
dc.subject Computer modeling es_ES
dc.subject Photothermal effect es_ES
dc.subject.classification TECNOLOGIA DE ALIMENTOS es_ES
dc.subject.classification MATEMATICA APLICADA es_ES
dc.title Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.cmpb.2022.106896 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094357-B-C21/ES/MODELADO Y EXPERIMENTACION PARA TERAPIAS ABLATIVAS INNOVADORAS/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/NSF//NSF-EAGER 1547014//WttB project/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/NSF//NSF-PIRE 1545852//WttB project/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/CONACYT//741249//Beca Mixta/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/CONACYT//246648//FORDECyT-PRONACES/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Arquitectura - Escola Tècnica Superior d'Arquitectura es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural es_ES
dc.description.bibliographicCitation Cano-Velázquez, MS.; Bon Corbín, J.; Llamazares, M.; Camacho-López, S.; Aguilar, G.; Hernández-Cordero, J.; Trujillo Guillen, M. (2022). Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant. Computer Methods and Programs in Biomedicine. 221:1-11. https://doi.org/10.1016/j.cmpb.2022.106896 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.cmpb.2022.106896 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 11 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 221 es_ES
dc.identifier.pmid 35617809 es_ES
dc.relation.pasarela S\467246 es_ES
dc.contributor.funder AGENCIA ESTATAL DE INVESTIGACION es_ES
dc.contributor.funder National Science Foundation, EEUU es_ES
dc.contributor.funder Consejo Nacional de Ciencia y Tecnología, México es_ES
upv.costeAPC 2440 es_ES


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