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Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance

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Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance

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Clara-Trujillo, S.; Tolosa, L.; Cordón, L.; Sempere, A.; Gallego-Ferrer, G.; Gómez Ribelles, JL. (2022). Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance. Biomaterials Advances. 135:1-13. https://doi.org/10.1016/j.bioadv.2022.212749

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Título: Novel microgel culture system as semi-solid three-dimensional in vitro model for the study of multiple myeloma proliferation and drug resistance
Autor: Clara-Trujillo, Sandra Tolosa, Laia Cordón, Lourdes Sempere, Amparo Gallego-Ferrer, Gloria Gómez Ribelles, José Luís
Entidad UPV: Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials
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Resumen:
[EN] Multiple myeloma (MM) is a hematological malignancy in which the patient's drug resistance is one of the main clinical problems. As 2D cultures do not recapitulate the cellular microenvironment, which has a key role ...[+]
Palabras clave: Multiple myeloma , Microgels , Microspheres , Emulsion polymerization , Drug resistance , Acrylic acid
Derechos de uso: Reconocimiento (by)
Fuente:
Biomaterials Advances. (eissn: 2772-9508 )
DOI: 10.1016/j.bioadv.2022.212749
Editorial:
Elsevier
Versión del editor: https://doi.org/10.1016/j.bioadv.2022.212749
Código del Proyecto:
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-106099RB-C41/ES/MICROGELES BIOMIMETICOS PARA EL ESTUDIO DE LA GENERACION DE RESISTENCIAS A FARMACOS EN EL MIELOMA MULTIPLE/
info:eu-repo/grantAgreement/ //FPU17%2F05810//AYUDA CONTRATO PREDOCTORAL FPU-CLARA TRUJILLO. PROYECTO: PERSONALIZED MEDICINE DEVICES FOR BLOOD CANCERS/
Agradecimientos:
This work was funded by the Spanish State Research Agency (AEI) through the PID2019-106099RB-C41/AEI/10.13039/501100011033 Project. CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008-2011, Iniciativa ...[+]
Tipo: Artículo

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