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Sex Effect in the Decision to Perform Invasive Coronary Angiography in Patients With Chronic Coronary Syndrome After Undergoing Vasodilator Stress MRI

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Sex Effect in the Decision to Perform Invasive Coronary Angiography in Patients With Chronic Coronary Syndrome After Undergoing Vasodilator Stress MRI

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dc.contributor.author Palau, Patricia es_ES
dc.contributor.author Núñez, Julio es_ES
dc.contributor.author Monmeneu, José V. es_ES
dc.contributor.author Lopez-Lereu, Maria P. es_ES
dc.contributor.author Gavara-Doñate, Josep es_ES
dc.contributor.author Rios-Navarro, Cesar es_ES
dc.contributor.author de Dios, Elena es_ES
dc.contributor.author Perez-Sole, Nerea es_ES
dc.contributor.author Marcos-Garces, Victor es_ES
dc.contributor.author Domínguez, Eloy es_ES
dc.contributor.author Moratal, David es_ES
dc.contributor.author Canoves, Joaquim es_ES
dc.contributor.author Miñana, Gema es_ES
dc.contributor.author Chorro, Francisco Javier es_ES
dc.contributor.author Bodi, Vicente es_ES
dc.date.accessioned 2023-11-10T19:05:18Z
dc.date.available 2023-11-10T19:05:18Z
dc.date.issued 2022-12 es_ES
dc.identifier.issn 1053-1807 es_ES
dc.identifier.uri http://hdl.handle.net/10251/199525
dc.description.abstract [EN] Background Stress cardiac MRI permits comprehensive evaluation of patients with known or suspected chronic coronary syndromes (CCS). The impact of sex on the use of invasive cardiac angiography (ICA) after vasodilator stress cardiac MRI is unclear. Purpose To evaluate the impact of sex on ICA use after vasodilator stress cardiac MRI. Study type Retrospective. Population A total of 6229 consecutive patients (age [mean +/- standard deviation] 65.2 +/- 11.5 years, 38.1% women). Field Strength/Sequence A 5-T; a steady-state free-precession cine sequence; stress first-pass perfusion imaging; late enhancement imaging. Assessment Patients underwent vasodilator stress cardiac MRI for known or suspected CCS. The ischemic burden (at stress first-pass perfusion imaging) was computed (17-segment model). Statistical Tests Multivariate logistic regression was used to evaluate the potential differential association between ischemic burden and use of cardiac MRI-related ICA across sex. Results A total of 1109 (17.8%) patients were referred to ICA, among which there were significantly more men (762, 19.7%) than women (347, 14.6%). Overall, after multivariate adjustment, female sex was not associated with lower use of ICA (odds ratio [OR] = 0.99; confidence interval [CI] 95%: 0.84-1.18, P = 0.934). However, significant sex differences were detected across ischemic burden. Whereas women with nonischemic vasodilator stress cardiac MRI (0 ischemic segments) were less commonly submitted to ICA (OR = 0.49; CI 95%: 0.35-0.69) in patients with ischemia (>1 ischemic segment), adjusted use of ICA was more frequent in women than men (OR = 1.27; CI 95%: 1.1-1.5). Data Conclusions In patients with known or suspected CCS submitted to undergo vasodilator stress cardiac MRI, cardiac MRI-related ICA may be overused in men without ischemia. Furthermore, ICA referral in patients with negative ischemia resulted in greater odds of revascularization in men. Evidence Level 3 Technical Efficacy Stage 5. es_ES
dc.description.sponsorship This work was supported by "Instituto de Salud Carlos III" and "Fondos Europeos de Desarrollo Regional FEDER" (grant numbers PI20/00637 and CIBERCV16/11/00486), by Conselleria de Educacio - Generalitat Valenciana (grant number PROMETEO/2021/008), and by the Spanish Society of Cardiology (grant number SEC/FECINV-CLI 21/024). es_ES
dc.language Inglés es_ES
dc.publisher John Wiley & Sons es_ES
dc.relation.ispartof Journal of Magnetic Resonance Imaging es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Coronary angiography es_ES
dc.subject Vasodilator stress MRI es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Sex Effect in the Decision to Perform Invasive Coronary Angiography in Patients With Chronic Coronary Syndrome After Undergoing Vasodilator Stress MRI es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1002/jmri.28163 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00637/ES/RESOLUCION DE LA OBSTRUCCION MICROVASCULAR TRAS UN INFARTO DE MIOCARDIO: EVALUACION DE LAS CONSECUENCIAS ESTRUCTURALES Y CLINICAS Y BUSQUEDA DE NUEVAS OPCIONES TERAPEUTICAS./ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/FEDER//CIBERCV16%2F11%2F00486/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00486/ES/ENFERMEDADES CARDIOVASCULARES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//PROMETEO%2F2021%2F008/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/Sociedad Española de Cardiología//SEC%2FFECINV-CLI 21%2F024/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials es_ES
dc.description.bibliographicCitation Palau, P.; Núñez, J.; Monmeneu, JV.; Lopez-Lereu, MP.; Gavara-Doñate, J.; Rios-Navarro, C.; De Dios, E.... (2022). Sex Effect in the Decision to Perform Invasive Coronary Angiography in Patients With Chronic Coronary Syndrome After Undergoing Vasodilator Stress MRI. Journal of Magnetic Resonance Imaging. 56(6):1680-1690. https://doi.org/10.1002/jmri.28163 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1002/jmri.28163 es_ES
dc.description.upvformatpinicio 1680 es_ES
dc.description.upvformatpfin 1690 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 56 es_ES
dc.description.issue 6 es_ES
dc.identifier.pmid 35344231 es_ES
dc.relation.pasarela S\481738 es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder Instituto de Salud Carlos III es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Sociedad Española de Cardiología es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES


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