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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA.

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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA.

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Pérez-Martínez, FC.; Carrión, B.; Lucío, MI.; Rubio, N.; Herrero, MA.; Vázquez, E.; Ceña, V. (2012). Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA. Biomaterials. 33(32):8152-8159. https://doi.org/10.1016/j.biomaterials.2012.07.038

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/201989

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Title: Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA.
Author: Pérez-Martínez, Francisco C. Carrión, Blanca Lucío, María Isabel Rubio, Noelia Herrero, Maria A. Vázquez, Ester Ceña, Valentín
UPV Unit: Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural
Issued date:
Abstract:
[EN] We synthesized a non-viral delivery system (f-CNH3) for small interfering RNA (siRNA) by anchoring a fourth-generation polyamidoamine dendrimer (G4-PAMAM) to carbon nanohorns (CNHs). Using this new compound, we delivered ...[+]
Subjects: Dendrimer , Gene therapy , Nanoparticle , SiRNA , Prostate cancer
Copyrigths: Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
Source:
Biomaterials. (issn: 0142-9612 )
DOI: 10.1016/j.biomaterials.2012.07.038
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.biomaterials.2012.07.038
Project ID:
info:eu-repo/grantAgreement/JCCM//PII1I09-0163-4002/ES/Papel De La Proteína P53 En La Activación Mitocondrial Durante Los Procesos Excitotóxicos/
info:eu-repo/grantAgreement/JCCM//POII10-0274-3182/ES/Dendrímeros como base de la terapia génica en la terapéutica de la osteopenia asociada a la diabetes mellitus/
info:eu-repo/grantAgreement/MICINN//BFU2011-30161-C02-01/ES/NANOPARTICULAS NO VIRALES COMO VECTORES PARA SIRNA EN CELULAS TUMORALES Y NEURONAS/
Thanks:
F.C.P-M. and B.C. are recipients of Torres Quevedo contracts from Ministerio de Ciencia e Innovacion (Spain) and NanoDrugs, S.L. This work has been supported, in part, by grants BFU2011-30161-C02-01 from Ministerio de ...[+]
Type: Artículo

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