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Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients

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Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients

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dc.contributor.author Frasson, Matteo es_ES
dc.contributor.author Flor, Blas es_ES
dc.contributor.author Ramos, José Luis es_ES
dc.contributor.author Granero-Castro, Pablo es_ES
dc.contributor.author Hervás-Marín, David es_ES
dc.contributor.author Alvarez, Miguel Angel es_ES
dc.contributor.author Garcia, Maria Jesus es_ES
dc.contributor.author Sanchez, Juan Manuel es_ES
dc.contributor.author Garcia-Granero, Eduardo es_ES
dc.date.accessioned 2024-02-05T19:02:53Z
dc.date.available 2024-02-05T19:02:53Z
dc.date.issued 2015-08 es_ES
dc.identifier.issn 0003-4932 es_ES
dc.identifier.uri http://hdl.handle.net/10251/202350
dc.description.abstract [EN] Objective: To determine pre-/intraoperative risk factors for anastomotic leak after colon resection for cancer and to create a practical instrument for predicting anastomotic leak risk. Background: Anastomotic leak is still the most dreaded complication in colorectal surgery. Many risk factors have been identified to date, but multicentric prospective studies on anastomotic leak after colon resection are lacking. Methods: Fifty-two hospitals participated in this prospective, observational study. Data of 3193 patients, operated for colon cancer with primary anastomosis without stoma, were included in a prospective online database (September 2011-September 2012). Forty-two pre-/intraoperative variables, related to patient, tumor, surgical procedure, and hospital, were analyzed as potential independent risk factors for anastomotic leak (60-day follow-up). A nomogram was created to easily predict the risk of anastomotic leak for a given patient. es_ES
dc.description.sponsorship The study was promoted by the "Spanish Association of Surgeons" ("Asociacion Espanola de Cirujanos"). The online database was created and maintained by "Oxon Epidemiology," sponsored by Takeda. es_ES
dc.language Inglés es_ES
dc.publisher Lippincott Williams & Wilkins es_ES
dc.relation.ispartof Annals of Surgery es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Anastomotic leak es_ES
dc.subject Colon cancer es_ES
dc.subject Colon resection es_ES
dc.subject Nomogram es_ES
dc.subject Risk factor es_ES
dc.subject.classification ESTADISTICA E INVESTIGACION OPERATIVA es_ES
dc.title Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1097/SLA.0000000000000973 es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Politécnica Superior de Alcoy - Escola Politècnica Superior d'Alcoi es_ES
dc.description.bibliographicCitation Frasson, M.; Flor, B.; Ramos, JL.; Granero-Castro, P.; Hervás-Marín, D.; Alvarez, MA.; Garcia, MJ.... (2015). Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients. Annals of Surgery. 262(2):321-330. https://doi.org/10.1097/SLA.0000000000000973 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1097/SLA.0000000000000973 es_ES
dc.description.upvformatpinicio 321 es_ES
dc.description.upvformatpfin 330 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 262 es_ES
dc.description.issue 2 es_ES
dc.identifier.pmid 25361221 es_ES
dc.relation.pasarela S\508230 es_ES
dc.contributor.funder Takeda Pharmaceutical Company, Ltd. es_ES


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