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Use of Fluorescence Spectroscopy and Chemometrics to Visualise Fluoroquinolones Photodegradation Major Trends: A Confirmation Study with Mass Spectrometry

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Use of Fluorescence Spectroscopy and Chemometrics to Visualise Fluoroquinolones Photodegradation Major Trends: A Confirmation Study with Mass Spectrometry

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dc.contributor.author Sciscenko, Iván Matías es_ES
dc.contributor.author García-Negueroles, Paula es_ES
dc.contributor.author Amat Payá, Ana María es_ES
dc.contributor.author Oller, Isabel es_ES
dc.contributor.author Escudero-Oñate, Carlos es_ES
dc.contributor.author Ferrando-Climent, Laura es_ES
dc.contributor.author Arqués Sanz, Antonio es_ES
dc.date.accessioned 2024-02-28T19:04:49Z
dc.date.available 2024-02-28T19:04:49Z
dc.date.issued 2023-01 es_ES
dc.identifier.uri http://hdl.handle.net/10251/202842
dc.description.abstract [EN] In this work, we employed EEM-PARAFAC (fluorescence excitation-emission matrices-parallel factor analysis) as a low-cost tool to study the oxidation pathways of (fluoro)quinolones. Amounts of 12.5 ¿M of enrofloxacin (ENR), ciprofloxacin (CIP), ofloxacin (OFL), oxolinic acid (OA), and flumequine (FLU), as individual solutions, were irradiated under UVA light. A 5-component PARAFAC model was obtained, four of them related to the parent pollutants, named as ENR-like (including CIP), OFL-like, OA-like, and FLU-like, and an additional one related to photoproducts, called ENRox-like (with an emission red-shift with respect to the ENR-like component). Mass spectrometry was employed to correlate the five PARAFAC components with their plausible molecular structures. Results indicated that photoproducts presenting: (i) hydroxylation or alkyl cleavages exhibited fingerprints analogous to those of the parent pollutants; (ii) defluorination and hydroxylation emitted within the ENRox-like region; (iii) the aforementioned changes plus piperazine ring cleavage emitted within the OA-like region. Afterwards, the five antibiotics were mixed in a single solution (each at a concentration of 0.25 ¿M) in seawater, PARAFAC being also able to deconvolute the fingerprint of humic-like substances. This approach could be a potential game changer in the analysis of (fluorescent) contaminants of emerging concern removals in complex matrices, giving rapid visual insights into the degradation pathways. es_ES
dc.description.sponsorship This work is part of a project that received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 765860 (AQUAlity). The paper reflects only the authors' view and the Agency is not responsible for any use that may be made of the information it contains. The authors also wish to thank the Spanish Ministry of Science and Innovation (MCI) for funding under the AquaEnAgri Project (Reference: PID2021-126400OB-C31). Further thanks goes to the Water JPI-Biodiversa COFUND Program for funding the BIORESET project and supporting the research of the scientist Laura Ferrando Climent. es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation.ispartof Molecules es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Antibiotics es_ES
dc.subject Low-cost analysis es_ES
dc.subject Pharmaceuticals es_ES
dc.subject Photolysis es_ES
dc.subject Seawater es_ES
dc.subject Transformation products es_ES
dc.subject Water treatments es_ES
dc.subject.classification QUIMICA FISICA es_ES
dc.title Use of Fluorescence Spectroscopy and Chemometrics to Visualise Fluoroquinolones Photodegradation Major Trends: A Confirmation Study with Mass Spectrometry es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/molecules28020777 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-126400OB-C31/ES/REVALORIZACION DE DIFERENTES AGUAS RESIDUALES MEDIANTE TECNOLOGIAS QUE PERMITAN MEJORAR EL NEXO AGUA-ENERGIA RENOVABLE-ALIMENTOS/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/765860/EU es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Textil y Papelera - Departament d'Enginyeria Tèxtil i Paperera es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Politécnica Superior de Alcoy - Escola Politècnica Superior d'Alcoi es_ES
dc.description.bibliographicCitation Sciscenko, IM.; García-Negueroles, P.; Amat Payá, AM.; Oller, I.; Escudero-Oñate, C.; Ferrando-Climent, L.; Arqués Sanz, A. (2023). Use of Fluorescence Spectroscopy and Chemometrics to Visualise Fluoroquinolones Photodegradation Major Trends: A Confirmation Study with Mass Spectrometry. Molecules. 28(2). https://doi.org/10.3390/molecules28020777 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/molecules28020777 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 28 es_ES
dc.description.issue 2 es_ES
dc.identifier.eissn 1420-3049 es_ES
dc.identifier.pmid 36677831 es_ES
dc.identifier.pmcid PMC9864895 es_ES
dc.relation.pasarela S\482483 es_ES
dc.contributor.funder AGENCIA ESTATAL DE INVESTIGACION es_ES
dc.contributor.funder COMISION DE LAS COMUNIDADES EUROPEA es_ES


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