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dc.contributor.author | Gavara-Doñate, Josep | es_ES |
dc.contributor.author | Merenciano-Gonzalez, Héctor | es_ES |
dc.contributor.author | Llopis-Lorente, Jordi | es_ES |
dc.contributor.author | Molina-García, Tamara | es_ES |
dc.contributor.author | Perez-Solé, Nerea | es_ES |
dc.contributor.author | De Dios, Elena | es_ES |
dc.contributor.author | Marcos-Garces, Víctor | es_ES |
dc.contributor.author | Monmeneu, José V. | es_ES |
dc.contributor.author | Lopez-Lereu, Maria P. | es_ES |
dc.contributor.author | Cànoves, Joaquim | es_ES |
dc.contributor.author | Clara Bonanad | es_ES |
dc.contributor.author | Moratal, David | es_ES |
dc.contributor.author | Nuñez, Julio | es_ES |
dc.contributor.author | Bayés-Genis, Antoni | es_ES |
dc.contributor.author | Sanchis, Juan | es_ES |
dc.date.accessioned | 2024-09-06T18:16:47Z | |
dc.date.available | 2024-09-06T18:16:47Z | |
dc.date.issued | 2024-02 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/207628 | |
dc.description.abstract | [EN] We aimed to assess the correlation of cardiovascular magnetic resonance (CMR)-derived epicardial adipose tissue (EAT) with infarct size (IS) and residual systolic function in ST-segment elevation myocardial infarction (STEMI). We enrolled patients discharged for a first anterior reperfused STEMI submitted to undergo CMR. EAT, left ventricular (LV) ejection fraction (LVEF), and IS were quantified at the 1-week (n = 221) and at 6-month CMR (n = 167). At 1-week CMR, mean EAT was 31 +/- 13 mL/m(2). Patients with high EAT volume (n = 72) showed larger 1-week IS. After adjustment, EAT extent was independently related to 1-week IS. In patients with large IS at 1 week (>30% of LV mass, n = 88), those with high EAT showed more preserved 6-month LVEF. This association persisted after adjustment and in a 1:1 propensity score-matched patient subset. Overall, EAT decreased at 6 months. In patients with large IS, a greater reduction of EAT was associated with more preserved 6-month LVEF. In STEMI, a higher presence of EAT was associated with a larger IS. Nevertheless, in patients with large infarctions, high EAT and greater subsequent EAT reduction were linked to more preserved LVEF in the chronic phase. This dual and paradoxical effect of EAT fuels the need for further research in this field. | es_ES |
dc.description.sponsorship | This work was supported by "Instituto de Salud Carlos III" and FEDER (grant numbers PI20/00637, PI23/01150, CB16/11/00403, CB16/11/00420, CB16/11/00486, CM21/00175), "Conselleria deEducacion-Generalitat Valenciana" (PROMETEO/2021/008), "Conselleria de Innovacion, Universidades,Ciencia y Sociedad Digital-Generalitat Valenciana" (CIGE/2022/26, AEST/2021/050, CIAEST/2021/27),"Agencia Estatal de Investigacion" (grant FJC2020-043981-I/AEI/10.13039/501100011033). | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | MDPI AG | es_ES |
dc.relation.ispartof | Diagnostics | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject | ST-segment elevation myocardial infarction | es_ES |
dc.subject | Cardiovascular magnetic resonance | es_ES |
dc.subject | Epicardial adipose tissue | es_ES |
dc.subject | Infarct size | es_ES |
dc.subject | Left ventricular ejection fraction | es_ES |
dc.subject.classification | TECNOLOGIA ELECTRONICA | es_ES |
dc.title | Impact of Epicardial Adipose Tissue on Infarct Size and Left Ventricular Systolic Function in Patients with Anterior ST-Segment Elevation Myocardial Infarction | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.3390/diagnostics14040368 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00637/ES/RESOLUCION DE LA OBSTRUCCION MICROVASCULAR TRAS UN INFARTO DE MIOCARDIO: EVALUACION DE LAS CONSECUENCIAS ESTRUCTURALES Y CLINICAS Y BUSQUEDA DE NUEVAS OPCIONES TERAPEUTICAS./ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00403/ES/ENFERMEDADES CARDIOVASCULARES/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00420/ES/ENFERMEDADES CARDIOVASCULARES/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00486/ES/ENFERMEDADES CARDIOVASCULARES/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GVA//CIGE%2F2022%2F26/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GVA//AEST%2F2021%2F050/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GVA//PROMETEO%2F2021%2F008/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GVA//CIAEST%2F2021%2F27/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ISCIII//CM21%2F00175/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ISCIII//PI23%2F01150/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/AEI//FJC2020-043981-I/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials | es_ES |
dc.description.bibliographicCitation | Gavara-Doñate, J.; Merenciano-Gonzalez, H.; Llopis-Lorente, J.; Molina-García, T.; Perez-Solé, N.; De Dios, E.; Marcos-Garces, V.... (2024). Impact of Epicardial Adipose Tissue on Infarct Size and Left Ventricular Systolic Function in Patients with Anterior ST-Segment Elevation Myocardial Infarction. Diagnostics. 14(4). https://doi.org/10.3390/diagnostics14040368 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/diagnostics14040368 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 14 | es_ES |
dc.description.issue | 4 | es_ES |
dc.identifier.eissn | 2075-4418 | es_ES |
dc.identifier.pmid | 38396407 | es_ES |
dc.identifier.pmcid | PMC10888463 | es_ES |
dc.relation.pasarela | S\520999 | es_ES |
dc.contributor.funder | Generalitat Valenciana | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | Agencia Estatal de Investigación | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad | es_ES |