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Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports

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Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports

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dc.contributor.author Coll Merino, Mª Carmen es_ES
dc.contributor.author Mondragón Martínez, Laura es_ES
dc.contributor.author Martínez Mañez, Ramón es_ES
dc.contributor.author Sancenón Galarza, Félix es_ES
dc.contributor.author Marcos Martínez, María Dolores es_ES
dc.contributor.author Soto Camino, Juan es_ES
dc.contributor.author Amoros del Toro, Pedro Jose es_ES
dc.contributor.author Pérez Payá, Enrique es_ES
dc.date.accessioned 2013-04-19T10:35:59Z
dc.date.issued 2011-02-01
dc.identifier.issn 1433-7851
dc.identifier.uri http://hdl.handle.net/10251/28070
dc.description.abstract Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, "zero release" supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides). © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. es_ES
dc.description.sponsorship We thank the Spanish Government (projects MAT2009-14564-C04, CB07/01/2012, and BIO2007 60066), the Generalitat Valencia (project PROMETEO/2009/016, PROMETEO/2010/005), and the CIBER-BBN for their support. en_EN
dc.language Español es_ES
dc.publisher Wiley-VCH Verlag es_ES
dc.relation Generalitat Valenciana projects PROMETEO es_ES
dc.relation Spanish Government (projects MAT2009 es_ES
dc.relation.ispartof Angewandte Chemie International Edition es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Controlled release es_ES
dc.subject Mesoporous materials es_ES
dc.subject Molecular gates es_ES
dc.subject Nanoparticles es_ES
dc.subject Peptides es_ES
dc.subject Controlled release systems es_ES
dc.subject Mesoporous Silica es_ES
dc.subject Mesoporous support es_ES
dc.subject Peptide sequences es_ES
dc.subject Silica es_ES
dc.subject Coordination compound es_ES
dc.subject Nanoparticle es_ES
dc.subject Peptide es_ES
dc.subject Peptide hydrolase es_ES
dc.subject Ruthenium es_ES
dc.subject Silicon dioxide es_ES
dc.subject Amino acid sequence es_ES
dc.subject Article es_ES
dc.subject Chemistry es_ES
dc.subject Kinetics es_ES
dc.subject Metabolism es_ES
dc.subject Molecular genetics es_ES
dc.subject Porosity es_ES
dc.subject Coordination Complexes es_ES
dc.subject Molecular Sequence Data es_ES
dc.subject Peptide Hydrolases es_ES
dc.subject.classification INGENIERIA DE LA CONSTRUCCION es_ES
dc.subject.classification QUIMICA INORGANICA es_ES
dc.subject.classification QUIMICA ORGANICA es_ES
dc.title Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports es_ES
dc.type Artículo es_ES
dc.embargo.lift 10000-01-01
dc.embargo.terms forever es_ES
dc.identifier.doi 10.1002/anie.201004133
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Química - Departament de Química es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic es_ES
dc.description.bibliographicCitation Coll Merino, MC.; Mondragón Martínez, L.; Martínez Mañez, R.; Sancenón Galarza, F.; Marcos Martínez, MD.; Soto Camino, J.; Amoros Del Toro, PJ.... (2011). Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports. Angewandte Chemie International Edition. 50:2138-2140. doi:10.1002/anie.201004133 es_ES
dc.description.accrualMethod Senia es_ES
dc.relation.publisherversion http://onlinelibrary.wiley.com/doi/10.1002/anie.201004133/pdf es_ES
dc.description.upvformatpinicio 2138 es_ES
dc.description.upvformatpfin 2140 es_ES
dc.type.version info:eu repo/semantics/publishedVersion es_ES
dc.description.volume 50 es_ES
dc.relation.senia 206704


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