- -

Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

  • Estadisticas de Uso

Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration

Show simple item record

Files in this item

dc.contributor.author Aznar Gimeno, Elena es_ES
dc.contributor.author Sancenón Galarza, Félix es_ES
dc.contributor.author Marcos Martínez, María Dolores es_ES
dc.contributor.author Martínez Mañez, Ramón es_ES
dc.contributor.author STROEVE, PIETER es_ES
dc.contributor.author Cano, Joan es_ES
dc.contributor.author AMOROS DEL TORO, PEDRO es_ES
dc.date.accessioned 2013-05-07T09:40:17Z
dc.date.issued 2012-12-19
dc.identifier.issn 0743-7463
dc.identifier.uri http://hdl.handle.net/10251/28622
dc.description.abstract This article focuses on the study of the release rate in a family of modified silica mesoporous supports. A collection of solids containing ethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontyl groups anchored on the pore outlets of mesoporous MCM-41 has been prepared and characterized. Controlled release from pore voids has been studied through the delivery of the dye complex tris(2,2¿-bipyridyl)ruthenium(II). Delivery rates were found to be dependent on the alkyl chain length anchored on the pore outlets of the mesoporous scaffolding. Moreover, release rates follow a Higuchi diffusion model, and Higuchi constants for the different hybrid solids have been calculated. A decrease of the Higuchi constants was observed as the alkyl chain used to tune the release profile is longer, confirming the effect that the different alkyl chains anchored into the pore mouths exerted on the delivery of the cargo. Furthermore, to better understand the relation between pore outlets decoration and release rate, studies using molecular dynamics simulations employing force-field methods have been carried out. A good agreement between the calculations and the experimental observations was observed. es_ES
dc.description.sponsorship Financial support from the Spanish Government (projects MAT2009-14564-C04-01 and MAT2009-14564-C04-04) and the Generalitat Valencia (project PROMETEO/2009/016) is gratefully acknowledged. en_EN
dc.language Inglés es_ES
dc.publisher American Chemical Society es_ES
dc.relation.ispartof Langmuir es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject.classification INGENIERIA DE LA CONSTRUCCION es_ES
dc.subject.classification QUIMICA INORGANICA es_ES
dc.subject.classification QUIMICA ORGANICA es_ES
dc.title Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration es_ES
dc.type Artículo es_ES
dc.embargo.lift 10000-01-01
dc.embargo.terms forever es_ES
dc.identifier.doi 10.1021/la204438j
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2009-14564-C04-01/ES/Nanomateriales Hibridos Para El Desarrollo De "Puertas Moleculares" De Aplicacion En Procesos De Reconocimiento Y Terapeutica Y Para La Deteccion De Explosivos/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/Generalitat Valenciana//PROMETEO09%2F2009%2F016/ES/Ayuda prometeo 2009 para el grupo de diseño y desarrollo de sensores/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2009-14564-C04-04/ES/Nanomateriales Mesoporosos Y Particulados Para El Diseño De Sistemas Sensores, Remediacion Y Aplicaciones Relacionadas Con La Energia/ / es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Química - Departament de Química es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic es_ES
dc.description.bibliographicCitation Aznar Gimeno, E.; Sancenón Galarza, F.; Marcos Martínez, MD.; Martínez Mañez, R.; Stroeve, P.; Cano, J.; Amoros Del Toro, P. (2012). Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration. Langmuir. 28:2986-2996. https://doi.org/10.1021/la204438j es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://pubs.acs.org/doi/ipdf/10.1021/la204438j es_ES
dc.description.upvformatpinicio 2986 es_ES
dc.description.upvformatpfin 2996 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 28 es_ES
dc.relation.senia 212645
dc.contributor.funder Generalitat Valenciana es_ES


This item appears in the following Collection(s)

Show simple item record