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Real-time observation of antigen¿antibody association using a low-cost biosensing system based on photonic bandgap structures

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Real-time observation of antigen¿antibody association using a low-cost biosensing system based on photonic bandgap structures

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dc.contributor.author García Castelló, Javier es_ES
dc.contributor.author Toccafondo, Veronica es_ES
dc.contributor.author Escorihuela Fuentes, Jorge es_ES
dc.contributor.author Bañuls Polo, Mª José es_ES
dc.contributor.author Maquieira Catala, Ángel es_ES
dc.contributor.author García-Rupérez, Jaime es_ES
dc.date.accessioned 2013-07-09T11:19:20Z
dc.date.available 2013-07-09T11:19:20Z
dc.date.issued 2012
dc.identifier.issn 0146-9592
dc.identifier.uri http://hdl.handle.net/10251/30876
dc.description This paper was published in OPTICS LETTERS and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://dx.doi.org/10.1364/OL.37.003684. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law en_EN
dc.description.abstract [EN] In this letter, we present experimental results of antibody detection using a biosensor based on photonic bandgap structures, which are interrogated using a power-based readout technique. This interrogation method allows a realtime monitoring of the association process between the antigen probes and the target antibodies, allowing the instantaneous observation of any interaction event between molecules. because etunable lasers and optical spectrum analyzers are avoided for the readout, a drastic reduction of the final cost of the platform is obtained. Furthermore, the performance of the biosensing system is significantly enhanced due to the large number of data values obtained per second. es_ES
dc.description.sponsorship This work was partially funded by the European Commission under contract FP7-295043-BELERA, from the Spanish Ministerio de Ciencia e Innovacion (MICINN) under contracts TEC2008-06333 and CTQ2010-15943 (subprogram BQU), and from Generalitat Valenciana through the PROMETEO grants 2010-008 and 2012-087.
dc.language Inglés es_ES
dc.publisher Optical Society of America es_ES
dc.relation.ispartof Optics Letters es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Integrated optics es_ES
dc.subject Sensors es_ES
dc.subject Photonic crystal waveguides es_ES
dc.subject.classification QUIMICA ANALITICA es_ES
dc.subject.classification TEORIA DE LA SEÑAL Y COMUNICACIONES es_ES
dc.title Real-time observation of antigen¿antibody association using a low-cost biosensing system based on photonic bandgap structures es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1364/OL.37.003684
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/295043/EU/Reinforcing carbon nanotubes and photonics research cooperation between the Belarusian State University of Informatics and Radioelectronics and the European Research Area/ en_EN
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//CTQ2010-15943/ES/ESTUDIO DE NUEVAS VIAS DE DESARROLLO DE BIOMEMS PARA SCREENING MASIVO. DEMOSTRACION DE CONCEPTO COMO HERRAMIENTA DE ANALISIS APLICABLE EN "OMICAS"./ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//TEC2008-06333/ES/DISPOSITIVOS NANOFOTONICOS EN SILICIO/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//PROMETEO%2F2010%2F008/ES/AYUDA PARA EL GRUPO SYM-IDM/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//PROMETEO%2F2012%2F087/
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Comunicaciones - Departament de Comunicacions es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Química - Departament de Química es_ES
dc.description.bibliographicCitation García Castelló, J.; Toccafondo, V.; Escorihuela Fuentes, J.; Bañuls Polo, MJ.; Maquieira Catala, Á.; García-Rupérez, J. (2012). Real-time observation of antigen¿antibody association using a low-cost biosensing system based on photonic bandgap structures. Optics Letters. 37(17):3684-3686. https://doi.org/10.1364/OL.37.003684 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1364/OL.37.003684 es_ES
dc.description.upvformatpinicio 3684 es_ES
dc.description.upvformatpfin 3686 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 37 es_ES
dc.description.issue 17 es_ES
dc.relation.senia 224045
dc.identifier.pmid 22940990
dc.contributor.funder European Commission
dc.contributor.funder Ministerio de Ciencia e Innovación
dc.contributor.funder Generalitat Valenciana
dc.description.references Luchansky, M. S., & Bailey, R. C. (2011). High-Q Optical Sensors for Chemical and Biological Analysis. Analytical Chemistry, 84(2), 793-821. doi:10.1021/ac2029024 es_ES
dc.description.references Qavi, A. J., & Bailey, R. C. (2010). Multiplexed Detection and Label-Free Quantitation of MicroRNAs Using Arrays of Silicon Photonic Microring Resonators. Angewandte Chemie International Edition, 49(27), 4608-4611. doi:10.1002/anie.201001712 es_ES
dc.description.references García-Rupérez, J., Toccafondo, V., Bañuls, M. J., Castelló, J. G., Griol, A., Peransi-Llopis, S., & Maquieira, Á. (2010). Label-free antibody detection using band edge fringes in SOI planar photonic crystal waveguides in the slow-light regime. Optics Express, 18(23), 24276. doi:10.1364/oe.18.024276 es_ES
dc.description.references Toccafondo, V., García-Rupérez, J., Bañuls, M. J., Griol, A., Castelló, J. G., Peransi-Llopis, S., & Maquieira, A. (2010). Single-strand DNA detection using a planar photonic-crystal-waveguide-based sensor. Optics Letters, 35(21), 3673. doi:10.1364/ol.35.003673 es_ES
dc.description.references Claes, T., Molera, J. G., De Vos, K., Schacht, E., Baets, R., & Bienstman, P. (2009). Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator. IEEE Photonics Journal, 1(3), 197-204. doi:10.1109/jphot.2009.2031596 es_ES
dc.description.references Scullion, M. G., Di Falco, A., & Krauss, T. F. (2011). Slotted photonic crystal cavities with integrated microfluidics for biosensing applications. Biosensors and Bioelectronics, 27(1), 101-105. doi:10.1016/j.bios.2011.06.023 es_ES
dc.description.references Zlatanovic, S., Mirkarimi, L. W., Sigalas, M. M., Bynum, M. A., Chow, E., Robotti, K. M., … Grot, A. (2009). Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration. Sensors and Actuators B: Chemical, 141(1), 13-19. doi:10.1016/j.snb.2009.06.007 es_ES
dc.description.references Sepúlveda, B., Río, J. S. del, Moreno, M., Blanco, F. J., Mayora, K., Domínguez, C., & Lechuga, L. M. (2006). Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices. Journal of Optics A: Pure and Applied Optics, 8(7), S561-S566. doi:10.1088/1464-4258/8/7/s41 es_ES
dc.description.references Claes, T., Bogaerts, W., & Bienstman, P. (2011). Vernier-cascade label-free biosensor with integrated arrayed waveguide grating for wavelength interrogation with low-cost broadband source. Optics Letters, 36(17), 3320. doi:10.1364/ol.36.003320 es_ES
dc.description.references Zinoviev, K. E., Gonzalez-Guerrero, A. B., Dominguez, C., & Lechuga, L. M. (2011). Integrated Bimodal Waveguide Interferometric Biosensor for Label-Free Analysis. Journal of Lightwave Technology, 29(13), 1926-1930. doi:10.1109/jlt.2011.2150734 es_ES
dc.description.references Densmore, A., Vachon, M., Xu, D.-X., Janz, S., Ma, R., Li, Y.-H., … Schmid, J. H. (2009). Silicon photonic wire biosensor array for multiplexed real-time and label-free molecular detection. Optics Letters, 34(23), 3598. doi:10.1364/ol.34.003598 es_ES
dc.description.references Castelló, J. G., Toccafondo, V., Pérez-Millán, P., Losilla, N. S., Cruz, J. L., Andrés, M. V., & García-Rupérez, J. (2011). Real-time and low-cost sensing technique based on photonic bandgap structures. Optics Letters, 36(14), 2707. doi:10.1364/ol.36.002707 es_ES
dc.description.references Krishnamoorthy, G., Bianca Beusink, J., & Schasfoort, R. B. M. (2010). High-throughput surface plasmon resonance imaging-based biomolecular kinetic screening analysis. Analytical Methods, 2(8), 1020. doi:10.1039/c0ay00112k es_ES


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