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Synthesis of ordered mesoporous silica templated with biocompatible surfactants and applications in controlled release of drugs

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Synthesis of ordered mesoporous silica templated with biocompatible surfactants and applications in controlled release of drugs

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dc.contributor.author Botella Asuncion, Pablo es_ES
dc.contributor.author Corma Canós, Avelino es_ES
dc.contributor.author Quesada Vilar, Manuel es_ES
dc.date.accessioned 2013-09-04T08:39:44Z
dc.date.available 2013-09-04T08:39:44Z
dc.date.issued 2012
dc.identifier.issn 0959-9428
dc.identifier.uri http://hdl.handle.net/10251/31741
dc.description.abstract [EN] A novel series of mesoporous silica materials has been developed by using non-ionic, biocompatible alkyl maltoside surfactants as organic structure directing agents and working under biomimetic conditions (e. g., room temperature and almost neutral pH) to avoid modifications of potential drugs occluded within. The obtained mesophases were tuned by changing the template and its concentration. These sugar surfactant-silica platforms were used as drug delivery carriers for ibuprofen, by encapsulating drug molecules within the hydrophobic core of the template micelles. The obtained surfactant-assisted delivery systems constitute a new approach towards controlled release of small therapeutic molecules. es_ES
dc.description.sponsorship The authors wish to thank CICYT (MAT2006-14274-C02-01) and CSIC (200880I092) for their financial support. We kindly appreciate the technical support of the Electronic Microscopy Service of UPV.
dc.language Inglés es_ES
dc.publisher Royal Society of Chemistry es_ES
dc.relation.ispartof Journal of Materials Chemistry es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Molecular-Sieves es_ES
dc.subject Room-Temperature es_ES
dc.subject Delivery System es_ES
dc.subject Neutral Ph es_ES
dc.subject Nanoparticles es_ES
dc.subject Water es_ES
dc.subject Mixtures es_ES
dc.subject Behavior es_ES
dc.subject Mcm-41 es_ES
dc.subject Cells es_ES
dc.subject Electron Microscopy Service of the UPV
dc.subject.classification QUIMICA ORGANICA es_ES
dc.title Synthesis of ordered mesoporous silica templated with biocompatible surfactants and applications in controlled release of drugs es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1039/c2jm16291a
dc.relation.projectID info:eu-repo/grantAgreement/MEC//MAT2006-14274-C02-01/ES/DISEÑO MOLECULAR DE NANOMATERIALES ESTRUCTURADOS ORGANICOS-INORGANICOS PARA SU APLICACION EN CATALISIS, SEPARACION DE GASES Y BIOMEDICA./ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/CSIC//200880I092/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Química - Departament de Química es_ES
dc.description.bibliographicCitation Botella Asuncion, P.; Corma Canós, A.; Quesada Vilar, M. (2012). Synthesis of ordered mesoporous silica templated with biocompatible surfactants and applications in controlled release of drugs. Journal of Materials Chemistry. 22(13):6394-6401. https://doi.org/10.1039/c2jm16291a es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1039/c2jm16291a es_ES
dc.description.upvformatpinicio 6394 es_ES
dc.description.upvformatpfin 6401 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 22 es_ES
dc.description.issue 13 es_ES
dc.relation.senia 217109
dc.contributor.funder Consejo Superior de Investigaciones Científicas
dc.contributor.funder Ministerio de Educación y Ciencia es_ES
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