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Noninvasive time and frequency predictors of long-standing atrial fibrillation early recurrence after electrical cardioversion

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Noninvasive time and frequency predictors of long-standing atrial fibrillation early recurrence after electrical cardioversion

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dc.contributor.author Alcaraz, Raúl es_ES
dc.contributor.author Hornero, Fernando es_ES
dc.contributor.author Rieta Ibañez, José Joaquín es_ES
dc.date.accessioned 2013-12-09T11:05:12Z
dc.date.available 2013-12-09T11:05:12Z
dc.date.issued 2011-05-23
dc.identifier.issn 0147-8389
dc.identifier.uri http://hdl.handle.net/10251/34355
dc.description.abstract Background: Several clinical factors have been studied to predict atrial fibrillation (AF) recurrence after electrical cardioversion (ECV) with limited predictive value. Methods: A method able to predict robustly long-standing AF early recurrence by characterizing noninvasively the electrical atrial activity (AA) with parameters related to its time course and spectral features is presented. To this respect, 63 patients (20 men and 43 women; mean age 73.4 ± 9.0 years; under antiarrhythmic drug treatment with amiodarone) who were referred for ECV of persistent AF were studied. During a 4-week follow-up, AF recurrence was observed in 41 patients (65.1%). Results: RR variability and the studied AA spectral features, including dominant atrial frequency (DAF), its first harmonic and their amplitude, provided poor statistical differences between groups. On the contrary, f waves power (fWP) and Sample Entropy (SampEn) of the AA behaved as very good predictors. Patients who relapsed to AF presented lower fWP (0.036 ± 0.019 vs 0.081 ± 0.029 n.u. 2, P < 0.001) and higher SampEn (0.107 ± 0.022 vs 0.086 ± 0.033, P < 0.01). Furthermore, fWP presented the highest predictive accuracy of 82.5%, whereas SampEn provided a 79.4%. The remaining features revealed accuracies lower than 70%. A stepwise discriminant analysis (SDA) provided a model based on fWP and SampEn with 90.5% of accuracy. Conclusions: The fWP has proved to predict long-standing AF early recurrence after ECV and can be combined with SampEn to improve its diagnostic ability. Furthermore, a thorough analysis of the results allowed outlining possible associations between these two features and the concomitant status of atrial remodeling. es_ES
dc.description.sponsorship This work was supported by the projects TEC2010-20633 from the Spanish Ministry of Science and Innovation and PII2C09-0224-5983 and PPII11-0194-8121 from Junta de Comunidades de Castilla-La Mancha. en_EN
dc.format.extent 10 es_ES
dc.language Inglés es_ES
dc.publisher wiley es_ES
dc.relation.ispartof Pacing and Clinical Electrophysiology es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Atrial remodeling es_ES
dc.subject Cardioversion es_ES
dc.subject Electrocardiographic signal processing es_ES
dc.subject Fibrillatory wave power es_ES
dc.subject Long-standing atrial fibrillation es_ES
dc.subject Sample entropy es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Noninvasive time and frequency predictors of long-standing atrial fibrillation early recurrence after electrical cardioversion es_ES
dc.type Artículo es_ES
dc.embargo.terms forever es_ES
dc.identifier.doi 10.1111/j.1540-8159.2011.03125.x
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//TEC2010-20633/ES/DESARROLLO Y APLICACION DE ESTIMADORES AVANZADOS DE ORGANIZACION PARA LA CLASIFICACION TERAPEUTICA Y EL SEGUIMIENTO DE PACIENTES CON FIBRILACION AURICULAR/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/Junta de Comunidades de Castilla-La Mancha//PII2C09-0224-5983/ES/Aplicación De Metodologías No Lineales Para La Estimación Robusta Y No Invasiva De La Organización En Fibrilación Auricular/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/Junta de Comunidades de Castilla-La Mancha//PPII11-0194-8121]/ES/PPII11-0194-8121]/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Alcaraz, R.; Hornero, F.; Rieta Ibañez, JJ. (2011). Noninvasive time and frequency predictors of long-standing atrial fibrillation early recurrence after electrical cardioversion. Pacing and Clinical Electrophysiology. 34(10):1241-1250. https://doi.org/10.1111/j.1540-8159.2011.03125.x es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1111/j.1540-8159.2011.03125.x es_ES
dc.description.upvformatpinicio 1241 es_ES
dc.description.upvformatpfin 1250 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 34 es_ES
dc.description.issue 10 es_ES
dc.relation.senia 216578
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
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