- -

Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Compartir/Enviar a

Citas

Estadísticas

Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials

Mostrar el registro completo del ítem

Zemzemi, N.; Bernabeu, MO.; Saiz Rodríguez, FJ.; Cooper, J.; Pathmanathan, P.; Mirams, GR.; Pitt-Francis, J.... (2013). Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials. British Journal of Pharmacology. 168(3):718-733. doi:10.1111/j.1476-5381.2012.02200.x.

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/34675

Ficheros en el ítem

Metadatos del ítem

Título: Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials
Autor:
Entidad UPV: Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Fecha difusión:
Resumen:
BACKGROUND AND PURPOSE Understanding drug effects on the heart is key to safety pharmacology assessment and anti-arrhythmic therapy development. Here our goal is to demonstrate the ability of computational models to ...[+]
Palabras clave: ECG modelling , Computer simulation , Drug , HERG , Sodium blockers , QT prolongation , QRS widening
Derechos de uso: Cerrado
Fuente:
British Journal of Pharmacology. (issn: 0007-1188 )
DOI: 10.1111/j.1476-5381.2012.02200.x
Editorial:
Wiley-Blackwell
Versión del editor: http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02200.x/pdf
Patrocinador:
European Commission preDiCT grant [DG-INFSO224381]
Medical Research Council Career Development Award
Tipo: Artículo

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro completo del ítem