Mas Font, N.; Galiana Guillem, I.; Mondragón Martínez, L.; Aznar Gimeno, E.; Climent Terol, E.; Cabedo Escrig, N.; Sancenón Galarza, F.... (2013). Enhanced Efficacy and Broadening of Antibacterial Action of Drugs Via the Use of Capped Mesoporous Nanoparticles. Chemistry - A European Journal. 19:11167-11171. https://doi.org/10.1002/chem.201302170
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/37344
Title:
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Enhanced Efficacy and Broadening of Antibacterial Action of Drugs Via the Use of Capped Mesoporous Nanoparticles
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Author:
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Mas Font, Nuria
Galiana Guillem, Irene
Mondragón Martínez, Laura
Aznar Gimeno, Elena
Climent Terol, Estela
Cabedo Escrig, Nuria
Sancenón Galarza, Félix
Murguía Ibáñez, José Ramón
Martínez Mañez, Ramón
Marcos Martínez, María Dolores
Amoros del Toro, Pedro
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UPV Unit:
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Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic
Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Instituto Agroforestal Mediterráneo - Institut Agroforestal Mediterrani
Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
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Issued date:
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Abstract:
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[EN] A novel nanodevice consisting of mesoporous nanoparticles loaded with vancomycin and capped with epsilon-poly-L-lysine (epsilon-PL) was prepared and its interaction with different Gram-negative bacteria studied. A ...[+]
[EN] A novel nanodevice consisting of mesoporous nanoparticles loaded with vancomycin and capped with epsilon-poly-L-lysine (epsilon-PL) was prepared and its interaction with different Gram-negative bacteria studied. A remarkable improvement in the efficacy of the antimicrobial drug epsilon-PL and a broadening of the antimicrobial spectrum of vancomycin is demonstrated.
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Subjects:
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epsilon-poly-L-lysine
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Vancomycin
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Nanoparticles
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Mesoporous materials
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Gated materials
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Copyrigths:
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Cerrado |
Source:
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Chemistry - A European Journal. (issn:
0947-6539
)
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DOI:
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10.1002/chem.201302170
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Publisher:
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Wiley-VCH Verlag
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Publisher version:
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http://onlinelibrary.wiley.com/doi/10.1002/chem.201302170/pdf
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Project ID:
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info:eu-repo/grantAgreement/MINECO//MAT2012-38429-C04-01/ES/DESARROLLO DE MATERIALES FUNCIONALIZADOS CON PUERTAS NANOSCOPICAS PARA APLICACIONES DE LIBERACION CONTROLADA Y SENSORES PARA LA DETECCION DE NITRATO AMONICO, SULFIDRICO Y CO/
info:eu-repo/grantAgreement/Generalitat Valenciana//PROMETEO09%2F2009%2F016/ES/Ayuda prometeo 2009 para el grupo de diseño y desarrollo de sensores/
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Thanks:
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The authors thank the Spanish Government (project MAT2012-38429-C04-01) the Generalitat Valenciana (project PROMETEO/2009/016) and the CIBER-BBN for their support. N.M. also thanks the Ministerio de Ciencia e Innovacion ...[+]
The authors thank the Spanish Government (project MAT2012-38429-C04-01) the Generalitat Valenciana (project PROMETEO/2009/016) and the CIBER-BBN for their support. N.M. also thanks the Ministerio de Ciencia e Innovacion for her FPI grant. L.M. also thanks Generalitat Valenciana for her post-doc VALI+D contract.
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Type:
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Artículo
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