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Applicator for RF Thermokeratoplasty: Feasibility Study Using Theoretical Modeling and Ex Vivo Experiments

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Applicator for RF Thermokeratoplasty: Feasibility Study Using Theoretical Modeling and Ex Vivo Experiments

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dc.contributor.author Trujillo Guillen, Macarena es_ES
dc.contributor.author Ribera, Vicente es_ES
dc.contributor.author Quesada, Rita es_ES
dc.contributor.author Berjano, Enrique es_ES
dc.date.accessioned 2014-05-23T07:25:04Z
dc.date.issued 2012
dc.identifier.issn 0090-6964
dc.identifier.uri http://hdl.handle.net/10251/37698
dc.description.abstract Radiofrequency (RF) thermokeratoplasty uses RF currents to alter the curvature of the cornea by means of thermal lesions. An RF applicator which combined a microkeratome suction ring and a circular electrode was designed with the aim of creating circular thermal lesions in a predictable, uniform and safe way. An experimental study was conducted on ex vivo porcine eyes. A theoretical model was also designed. The experimental results showed a lesion depth of 34.2 ± 11.0% of corneal thickness at a constant voltage of 50 V up to roll-off (1000 X of impedance). With a voltage of 30 V for 30 s the mean depth was 36.8 ± 8.1%. The progress of electrical impedance throughout heating and lesion dimensions were used to compare the experimental and theoretical results. Both the impedance evolution and lesion dimensions obtained from the theoretical model showed good agreement with the experimental ¿ndings. The ¿ndings suggest that the new applicator could be a suitable option for creating uniform circular thermal lesions. es_ES
dc.description.sponsorship This work received financial support from the Spanish "Plan Nacional de I+D+I del Ministerio de Ciencia e Innovacion" Grant No. TEC2008-01369/TEC and FEDER Project MTM2010-14909. The translation of this paper was partially funded by the Universitat Politecnica de Valencia, Spain. en_EN
dc.language Inglés es_ES
dc.publisher Springer Verlag (Germany) es_ES
dc.relation.ispartof Annals of Biomedical Engineering es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Conductive keratoplasty es_ES
dc.subject Cornea es_ES
dc.subject Ex vivo experiments es_ES
dc.subject Ophthalmology es_ES
dc.subject Radiofrequency heating es_ES
dc.subject Theoretical modeling es_ES
dc.subject Thermokeratoplasty es_ES
dc.subject.classification MATEMATICA APLICADA es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Applicator for RF Thermokeratoplasty: Feasibility Study Using Theoretical Modeling and Ex Vivo Experiments es_ES
dc.type Artículo es_ES
dc.embargo.lift 10000-01-01
dc.embargo.terms forever es_ES
dc.identifier.doi 10.1007/s10439-011-0492-1
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//TEC2008-01369/ES/MODELOS COMPUTACIONALES E INVESTIGACION EXPERIMENTAL EN EL ESTUDIO DE TECNICAS QUIRURGICAS DE CALENTAMIENTO DE TEJIDOS BIOLOGICOS MEDIANTE CORRIENTES DE RADIOFRECUENCIA./ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MTM2010-14909/ES/HIPERCICLICIDAD Y CAOS DE OPERADORES/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Matemática Aplicada - Departament de Matemàtica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Trujillo Guillen, M.; Ribera, V.; Quesada, R.; Berjano, E. (2012). Applicator for RF Thermokeratoplasty: Feasibility Study Using Theoretical Modeling and Ex Vivo Experiments. Annals of Biomedical Engineering. 40(5):1182-1191. https://doi.org/10.1007/s10439-011-0492-1 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1007/s10439-011-0492-1 es_ES
dc.description.upvformatpinicio 1182 es_ES
dc.description.upvformatpfin 1191 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 40 es_ES
dc.description.issue 5 es_ES
dc.relation.senia 235498
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