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Detection of antibiotics in sheep milk by receptor-binding assays

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Detection of antibiotics in sheep milk by receptor-binding assays

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dc.contributor.author Beltrán Martínez, Mª Carmen es_ES
dc.contributor.author Althaus, R.L. es_ES
dc.contributor.author Berruga Fernandez, Maria Isabel es_ES
dc.contributor.author Molina Casanova, Ana es_ES
dc.contributor.author Molina Pons, Mª Pilar es_ES
dc.date.accessioned 2015-01-12T13:22:57Z
dc.date.available 2015-01-12T13:22:57Z
dc.date.issued 2014-02
dc.identifier.issn 0958-6946
dc.identifier.uri http://hdl.handle.net/10251/45994
dc.description.abstract Receptor-binding assays to detect antibiotics in sheep milk were evaluated. Specificity of the Betastar Combo, SNAP and Twinsensor(BT) tests was optimal using inhibitor-free bulk sheep milk (99-100%), and no differences between the visual or instrumental classification were found. For individual sheep milk free of antibiotics, specificity was elevated by the Betastar Combo and SNAP tests. However, lower specificity was obtained by the TwinsensorBT test, especially in the last weeks of the lactation period. Regarding cross-reactions, interferences related to drugs other than beta-lactams and tetracyclines were not detected. Furthermore, the use of azidiol, as a preservative of milk, had no effect on the test. In all cases, the detection capability was able to detect most b-lactams and tetracyclines at or below maximum residues limits. The receptor-binding tests evaluated showed a very good performance in the detection of antibiotics in sheep milk, thus being suitable for milk quality control programmes es_ES
dc.description.sponsorship This work forms part of the Project AGL2009-11524 financed by the Ministerio de Ciencia e Innovacion (Madrid, Spain). The authors are grateful to Fatro, S.p.A. (Bologna, Italy) and ACS Dobfar, S.p.A. (Milan, Italy) for kindly providing cefacetrile and desacetylcefapirin, respectively. Moreover, the authors wish to thank DSM Food Specialties (Delft, The Netherlands), IDEXX Laboratories (Westbrook, ME), Neogen Corporation (Lansing MI), and Unisensor (Liege, Belgium) for their technical support. en_EN
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation info:eu-repo/grantAgreement/MICINN//AGL2009-11524/ES/Estrategia Analitica Para La Deteccion De Residuos De Antibioticos En La Leche De Oveja Y Cabra/ es_ES
dc.relation.ispartof International Dairy Journal es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Beta-lactam antibiotics es_ES
dc.subject Ewes milk es_ES
dc.subject Screening-test es_ES
dc.subject Validation es_ES
dc.subject Residues es_ES
dc.subject Tests es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.title Detection of antibiotics in sheep milk by receptor-binding assays es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.idairyj.2013.09.006
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Ciencia y Tecnología Animal - Institut de Ciència i Tecnologia Animal es_ES
dc.description.bibliographicCitation Beltrán Martínez, MC.; Althaus, R.; Berruga Fernandez, MI.; Molina Casanova, A.; Molina Pons, MP. (2014). Detection of antibiotics in sheep milk by receptor-binding assays. International Dairy Journal. 34(2):184-189. https://doi.org/10.1016/j.idairyj.2013.09.006 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.idairyj.2013.09.006 es_ES
dc.description.upvformatpinicio 184 es_ES
dc.description.upvformatpfin 189 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 34 es_ES
dc.description.issue 2 es_ES
dc.relation.senia 257151
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES


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