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Determination of the parameters affecting electrospun chitosan fiber size distribution and morphology

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Determination of the parameters affecting electrospun chitosan fiber size distribution and morphology

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dc.contributor.author Sencadas, Vitor Joao Gomes Da Silva es_ES
dc.contributor.author Correia, Daniela Maria es_ES
dc.contributor.author Areias Cepa, Anabela es_ES
dc.contributor.author Botelho, G. es_ES
dc.contributor.author Fonseca, A.M. es_ES
dc.contributor.author Neves, I.C. es_ES
dc.contributor.author Gómez Ribelles, José Luís es_ES
dc.contributor.author Lanceros Mendez, Senen
dc.date.accessioned 2015-03-16T09:42:01Z
dc.date.available 2015-03-16T09:42:01Z
dc.date.issued 2012-01-15
dc.identifier.issn 0144-8617
dc.identifier.uri http://hdl.handle.net/10251/48059
dc.description.abstract The production of chitosan nanofiber mats by electrospinning presents serious difficulties due to the lack of suitable solvents and the strong influence of processing parameters on the fiber properties. Two are the main problems to be solved: to control the properties of the solution in order to obtain large area uniform fiber mats by having a stable flow rate and to avoid sparks during the process, damaging the fiber mats. In this work chitosan electrospun mats have been prepared form solutions of trifluoroacetic acid/dichloromethanemixtures, allowing solving the aforementionedproblems.Mats withuniformfibers of submicron diameters without beads were obtained. Further, the influence of the different solution and process parameters on the mean fiber diameter and on the width of the distribution of the fiber sizes has been assessed. Solvent composition, needle diameter, applied voltage and traveling distance were the parameters considered in this study. es_ES
dc.description.sponsorship This work is funded by FEDER funds through the “Programa Operacional Factores de Competitividade – COMPETE” and by national funds by FCT – Fundac ̧ ão para a Ciência e a Tecnologia, project references NANO/NMed-SD/0156/2007. VS thanks the FCT for the SFRH/BPD/63148/2009 grants. JLGR acknowledge the sup- port of the Spanish Ministry of Science and Innovation through project No. MAT2010-21611-C03-01 (including the FEDER finan- cial support) and Programa Nacional de Internacionalización de la I+D project EUI2008-00126. Funding for research in the field of Regenerative Medicine through the collaboration agreement from the Conselleria de Sanidad (Generalitat Valenciana), and the Insti- tuto de Salud Carlos III (Ministry of Science and Innovation) is also acknowledged. Thanks are due to the National NMR Network that was purchased within the framework of the National Program for Scientific Re-equipment, contract REDE/1517/RMN/2005 with funds from POCI 2010 (FEDER) and FCT. Also thank to the UPV Microscopy Service for the use of their lab. en_EN
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Carbohydrate Polymers es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Chitosan es_ES
dc.subject Electrospinning es_ES
dc.subject Nanofiber es_ES
dc.subject Processing es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title Determination of the parameters affecting electrospun chitosan fiber size distribution and morphology es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.carbpol.2011.09.017
dc.relation.projectID info:eu-repo/grantAgreement/FCT/SFRH/SFRH/BPD/63148/2009/PT/ en_EN
dc.relation.projectID info:eu-repo/grantAgreement/FCT/National Program for Scientific Re-equipment/REDE/1517/RMN/2005/PT es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2010-21611-C03-01/ES/MATERIALES BIOESTABLES Y BIOREABSORBIBLES A LARGO PLAZO COMO SOPORTES MACROPOROSOS PARA LA REGENERACION DEL CARTILAGO ARTICULAR/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F63148%2F2009/PT/ELECTROACTIVE MATERIALS BASED POROUS MEMBRANES AND SCAFFOLDS FOR BIOMEDICAL APPLICATIONS/
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//EUI2008-00126/ES/SMART JOINT IMPLANTS USING BIONANOCOMPOSITES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/FCT/5876-PPCDTI/109368/PT/“Smart joint implants using bionanocomposites-(SIMBIO)”/
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular es_ES
dc.description.bibliographicCitation Sencadas, VJGDS.; Correia, DM.; Areias Cepa, A.; Botelho, G.; Fonseca, A.; Neves, I.; Gómez Ribelles, JL.... (2012). Determination of the parameters affecting electrospun chitosan fiber size distribution and morphology. Carbohydrate Polymers. 87(2):1295-1301. https://doi.org/10.1016/j.carbpol.2011.09.017 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.carbpol.2011.09.017 es_ES
dc.description.upvformatpinicio 1295 es_ES
dc.description.upvformatpfin 1301 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 87 es_ES
dc.description.issue 2 es_ES
dc.relation.senia 239466
dc.identifier.eissn 1879-1344
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Fundação para a Ciência e a Tecnologia, Portugal


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