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Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

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Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

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Vendrell, A.; Martínez Pastor, MM.; González-Novo, A.; Pascual-Ahuir Giner, MD.; Sinclair, DA.; Proft, M.; Posas, F. (2011). Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase. EMBO Reports. 12(10):1062-1068. doi:10.1038/embor.2011.154

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Title: Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase
Author:
UPV Unit: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Issued date:
Abstract:
[EN]Exposure of yeast to high osmolarity induces a transient activation of the Hog1 stress-activated protein kinase (SAPK), which is required for cell survival under these conditions. However, sustained activation of ...[+]
Subjects: Cell death , Hog1 , SCF , SAPK , Sir2
Copyrigths: Reserva de todos los derechos
Source:
EMBO Reports. (issn: 1469-221X ) (eissn: 1469-3178 )
DOI: 10.1038/embor.2011.154
Publisher:
EMBO Press
Publisher version: http://dx.doi.org/10.1038/embor.2011.154
Project ID: info:eu-repo/grantAgreement/EC/FP7/201142
Thanks:
We thank L. Subirana, S. Ovejas and O. Fornas for technical support; G. Ammerer, J. Clotet, X. Escote and G. Mas for their helpful advice and contribution; and E. de Nadal for constant advice and support. This work was ...[+]
Type: Artículo

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