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Treatment with cholesterol-loaded methy-ß-cyclodextrin increased the cholesterol in rabbit oocytes, but did not improve developmental competence of cryopreserved oocytes

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Treatment with cholesterol-loaded methy-ß-cyclodextrin increased the cholesterol in rabbit oocytes, but did not improve developmental competence of cryopreserved oocytes

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Jiménez Trigos, ME.; Vicente Antón, JS.; Moce Cervera, ET.; Naturil Alfonso, C.; Fernández González, R.; Gutierrez Adan, A.; Marco Jiménez, F. (2013). Treatment with cholesterol-loaded methy-ß-cyclodextrin increased the cholesterol in rabbit oocytes, but did not improve developmental competence of cryopreserved oocytes. Cryobiology. 67(1):106-108. doi:10.1016/j.cryobiol.2013.05.006

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Title: Treatment with cholesterol-loaded methy-ß-cyclodextrin increased the cholesterol in rabbit oocytes, but did not improve developmental competence of cryopreserved oocytes
Author:
UPV Unit: Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal
Issued date:
Abstract:
Membrane cholesterol:phospholipids ratio is an important determinant of cell chilling sensitivity. At low temperatures, major membrane destabilisation occurs when the membrane undergoes a phase transition. To increase ...[+]
Subjects: Cholesterol , Cyclodextrin , Vitrification , Cryotop , Slow-freezing
Copyrigths: Cerrado
Source:
Cryobiology. (issn: 0011-2240 )
DOI: 10.1016/j.cryobiol.2013.05.006
Publisher:
Elsevier
Publisher version: http://dx.doi.org/10.1016/j.cryobiol.2013.05.006
Thanks:
This work was supported by the Spanish Research Project AGL2011-30170-C02-01 and by funds from the Generalitat Valenciana Research Programme (Prometeo 2009/125). Estrella Jimenez was supported by a research Grant from the ...[+]
Type: Artículo

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