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dc.contributor.author | Lago, M. A. | es_ES |
dc.contributor.author | Rupérez Moreno, María José | es_ES |
dc.contributor.author | Martínez Martínez, Francisco | es_ES |
dc.contributor.author | Monserrat Aranda, Carlos | es_ES |
dc.contributor.author | Larra, E. | es_ES |
dc.contributor.author | Gueell, J. L. | es_ES |
dc.contributor.author | Peris-Martinez, C. | es_ES |
dc.date.accessioned | 2015-06-02T11:15:16Z | |
dc.date.available | 2015-06-02T11:15:16Z | |
dc.date.issued | 2015-01 | |
dc.identifier.issn | 0021-9290 | |
dc.identifier.uri | http://hdl.handle.net/10251/51140 | |
dc.description.abstract | This work presents a methodology for the in vivo characterization of the complete biomechanical behavior of the human cornea of each patient. Specifically, the elastic constants of a hyperelastic, second-order Ogden model were estimated for 24 corneas corresponding to 12 patients. The finite element method was applied to simulate the deformation of human corneas due to non-contact tonometry, and an iterative search controlled by a genetic heuristic was used to estimate the elastic parameters that most closely approximates the simulated deformation to the real one. The results from a synthetic experiment showed that these parameters can be estimated with an error of about 5%. The results of 24 in vivo corneas showed an overlap of about 90% between simulation and real deformed cornea and a modified Hausdorff distance of 25 mu m, which indicates the great accuracy of the proposed methodology. (C) 2014 Elsevier Ltd. All rights reserved. | es_ES |
dc.description.sponsorship | This project has been partially funded by MECD (reference AP2009-2414) and MINECO (INNPACTO, IPT-2012-0495-300000). | en_EN |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Journal of Biomechanics | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Biomechanical characterization | es_ES |
dc.subject | Parameter optimization | es_ES |
dc.subject | Cornea | es_ES |
dc.subject.classification | LENGUAJES Y SISTEMAS INFORMATICOS | es_ES |
dc.title | A new methodology for the in vivo estimation of the elastic constants that characterize the patient-specific biomechanical behavior of the human cornea | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.jbiomech.2014.11.009 | |
dc.relation.projectID | info:eu-repo/grantAgreement/ME//AP2009-2414/ES/AP2009-2414/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//IPT-2012-0495-300000/ES/Planificación quirúrgica en el tratamiento de Ectasias y Cirugía Refractiva. ECTASIA/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano - Institut Interuniversitari d'Investigació en Bioenginyeria i Tecnologia Orientada a l'Ésser Humà | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Sistemas Informáticos y Computación - Departament de Sistemes Informàtics i Computació | es_ES |
dc.description.bibliographicCitation | Lago, MA.; Rupérez Moreno, MJ.; Martínez Martínez, F.; Monserrat Aranda, C.; Larra, E.; Gueell, JL.; Peris-Martinez, C. (2015). A new methodology for the in vivo estimation of the elastic constants that characterize the patient-specific biomechanical behavior of the human cornea. Journal of Biomechanics. 48(1):38-43. https://doi.org/10.1016/j.jbiomech.2014.11.009 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.jbiomech.2014.11.009 | es_ES |
dc.description.upvformatpinicio | 38 | es_ES |
dc.description.upvformatpfin | 43 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 48 | es_ES |
dc.description.issue | 1 | es_ES |
dc.relation.senia | 278630 | |
dc.contributor.funder | Ministerio de Educación | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad | es_ES |