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Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy

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Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy

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dc.contributor.author Shepherd, Tony es_ES
dc.contributor.author Teräs, Mika es_ES
dc.contributor.author Beichel, Reinhard R. es_ES
dc.contributor.author Boellaard, Ronald es_ES
dc.contributor.author Bruynooghe, Michel es_ES
dc.contributor.author Dicken, Volker es_ES
dc.contributor.author Gooding, Mark J. es_ES
dc.contributor.author Julyan, Peter J. es_ES
dc.contributor.author Lee, John A. es_ES
dc.contributor.author Lefèvre, Sébastien es_ES
dc.contributor.author Mix, Michael es_ES
dc.contributor.author Naranjo Ornedo, Valeriana es_ES
dc.contributor.author Wu, Xiaodong es_ES
dc.contributor.author Zaidi, Habib es_ES
dc.contributor.author Zeng,Ziming es_ES
dc.contributor.author Minn, Heikki es_ES
dc.date.accessioned 2015-10-21T06:13:21Z
dc.date.available 2015-10-21T06:13:21Z
dc.date.issued 2012-11
dc.identifier.issn 0278-0062
dc.identifier.uri http://hdl.handle.net/10251/56282
dc.description.abstract [EN] The impact of positron emission tomography (PET) on radiation therapy is held back by poor methods of defining functional volumes of interest. Many new software tools are being proposed for contouring target volumes but the different approaches are not adequately compared and their accuracy is poorly evaluated due to the ill-definition of ground truth. This paper compares the largest cohort to date of established, emerging and proposed PET contouring methods, in terms of accuracy and variability. We emphasize spatial accuracy and present a new metric that addresses the lack of unique ground truth. Thirty methods are used at 13 different institutions to contour functional volumes of interest in clinical PET/CT and a custom-built PET phantom representing typical problems in image guided radiotherapy. Contouring methods are grouped according to algorithmic type, level of interactivity and how they exploit structural information in hybrid images. Experiments reveal benefits of high levels of user interaction, as well as simultaneous visualization of CT images and PET gradients to guide interactive procedures. Method-wise evaluation identifies the danger of over-automation and the value of prior knowledge built into an algorithm. es_ES
dc.description.sponsorship For retrospective patient data and manual ground truth delineation, the authors wish to thank S. Suilamo, K. Lehtio, M. Mokka, and H. Minn at the Department of Oncology and Radiotherapy, Turku University Hospital, Finland. This study was funded by the Finnish Cancer Organisations.
dc.language Inglés es_ES
dc.publisher Institute of Electrical and Electronics Engineers (IEEE) es_ES
dc.relation Finnish Cancer Organisations es_ES
dc.relation.ispartof IEEE Transactions on Medical Imaging es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Human computer interaction es_ES
dc.subject Image segmentation es_ES
dc.subject Oncology es_ES
dc.subject Performance evaluation es_ES
dc.subject Phantoms es_ES
dc.subject Positron emission tomography (PET) es_ES
dc.subject.classification TEORIA DE LA SEÑAL Y COMUNICACIONES es_ES
dc.title Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1109/TMI.2012.2202322
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Comunicaciones - Departament de Comunicacions es_ES
dc.description.bibliographicCitation Shepherd, T.; Teräs, M.; Beichel, RR.; Boellaard, R.; Bruynooghe, M.; Dicken, V.; Gooding, MJ.... (2012). Comparative Study With New Accuracy Metrics for Target Volume Contouring in PET Image Guided Radiation Therapy. IEEE Transactions on Medical Imaging. 31(12):2006-2024. doi:10.1109/TMI.2012.2202322 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion Http://dx.doi.org/10.1109/TMI.2012.2202322 es_ES
dc.description.upvformatpinicio 2006 es_ES
dc.description.upvformatpfin 2024 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 31 es_ES
dc.description.issue 12 es_ES
dc.relation.senia 234590 es_ES
dc.identifier.pmid 22692898
dc.identifier.pmcid PMC5570440


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