- -

Synthesis of the ortho/meta/para Isomers of relevant pharmaceutical compounds by coupling a sonogashira reaction with a regioselective hydration

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

Synthesis of the ortho/meta/para Isomers of relevant pharmaceutical compounds by coupling a sonogashira reaction with a regioselective hydration

Show full item record

Leyva Perez, A.; Cabrero Antonino, JR.; Rubio Marqués, P.; Al-Resayes, SI.; Corma Canós, A. (2014). Synthesis of the ortho/meta/para Isomers of relevant pharmaceutical compounds by coupling a sonogashira reaction with a regioselective hydration. ACS Catalysis. 4(3):722-731. doi:10.1021/cs401075z

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/58372

Files in this item

Item Metadata

Title: Synthesis of the ortho/meta/para Isomers of relevant pharmaceutical compounds by coupling a sonogashira reaction with a regioselective hydration
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
Aryl ketones substituted in ortho, meta, and para position are prepared by a palladium-catalyzed Sonogashira reaction followed by a regioselective hydration of the soformed alkyne with triflimidic acid or a gold catalyst, ...[+]
Subjects: Butyrophenones , Antipsychotics , NSAIDs , Sonogashira reaction , Regioselective hydration
Copyrigths: Cerrado
Source:
ACS Catalysis. (issn: 2155-5435 )
DOI: 10.1021/cs401075z
Publisher:
American Chemical Society
Publisher version: http://dx.doi.org/10.1021/cs401075z
Description: This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Catalysis, copyright © American Chemical Society after peer review and technical editing by the publisher.
Thanks:
Financial support by the Severo Ochoa program and Consolider-Ingenio 2010 (proyecto MULTICAT) from MCIINN is acknowledged, and also to the King Saud University. A.L.-P. thanks ITQ for a contract. J.R. C.-A. and P.R.M. thank ...[+]
Type: Artículo

This item appears in the following Collection(s)

Show full item record