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Mapping and Introgression of QTL Involved in Fruit Shape Transgressive Segregation into 'Piel de Sapo' Melon (Cucucumis melo L.)

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Mapping and Introgression of QTL Involved in Fruit Shape Transgressive Segregation into 'Piel de Sapo' Melon (Cucucumis melo L.)

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dc.contributor.author Díaz Bermúdez, Aurora es_ES
dc.contributor.author Zarouri, Belkacem es_ES
dc.contributor.author Fergany, Mohamed es_ES
dc.contributor.author Eduardo, Iban es_ES
dc.contributor.author Álvarez, José A. es_ES
dc.contributor.author Picó Sirvent, María Belén es_ES
dc.contributor.author Monforte Gilabert, Antonio José es_ES
dc.date.accessioned 2016-01-13T12:37:27Z
dc.date.available 2016-01-13T12:37:27Z
dc.date.issued 2014-08
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/10251/59822
dc.description.abstract A mapping F-2 population from the cross 'Piel de Sapo' x PI124112 was selectively genotyped to study the genetic control of morphological fruit traits by QTL (Quantitative Trait Loci) analysis. Ten QTL were identified, five for FL (Fruit Length), two for FD (Fruit Diameter) and three for FS (Fruit Shape). At least one robust QTL per character was found, flqs8.1 (LOD = 16.85, R-2 = 34%), fdqs12.1 (LOD = 3.47, R-2 = 11%) and fsqs8.1 (LOD = 14.85, R-2 = 41%). flqs2.1 and fsqs2.1 cosegregate with gene a (andromonoecious), responsible for flower sex determination and with pleiotropic effects on FS. They display a positive additive effect (a) value, so the PI124112 allele causes an increase in FL and FS, producing more elongated fruits. Conversely, the negative a value for flqs8.1 and fsqs8.1 indicates a decrease in FL and FS, what results in rounder fruits, even if PI124112 produces very elongated melons. This is explained by a significant epistatic interaction between fsqs2.1 and fsqs8.1, where the effects of the alleles at locus a are attenuated by the additive PI124112 allele at fsqs8.1. Roundest fruits are produced by homozygous for PI124112 at fsqs8.1 that do not carry any dominant A allele at locus a (PiPiaa). A significant interaction between fsqs8.1 and fsqs12.1 was also detected, with the alleles at fsqs12.1 producing more elongated fruits. fsqs8.1 seems to be allelic to QTL discovered in other populations where the exotic alleles produce elongated fruits. This model has been validated in assays with backcross lines along 3 years and ultimately obtaining a fsqs8.1-NIL (Near Isogenic Line) in 'Piel de Sapo' background which yields round melons. es_ES
dc.description.sponsorship This work was supported by grants AGL2009-12698-C02-02 and AGL2012-40130-C02-02 from the Spanish Ministry of Economy and Competitiveness to AJM. AD was supported by a JAE-Doc contract from CSIC, MF by a Postdoctoral contract from GRAG, IE by a fellowship from the former Spanish Ministry of Education and BZ by a fellowship from Instituto Agronomico Mediterraneo de Zaragoza (IAMZ), Spain. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. en_EN
dc.language Inglés es_ES
dc.publisher Public Library of Science es_ES
dc.relation.ispartof PLoS ONE es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Melón piel de sapo es_ES
dc.subject.classification GENETICA es_ES
dc.title Mapping and Introgression of QTL Involved in Fruit Shape Transgressive Segregation into 'Piel de Sapo' Melon (Cucucumis melo L.) es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1371/journal.pone.0104188
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//AGL2009-12698-C02-02/ES/El Control Genetico De La Forma Del Fruto Y Domesticacion Del Melon En Varias Fuentes De Germoplasma/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//AGL2012-40130-C02-02/ES/DESCIFRANDO LA BASE GENETICA DE LA MORFOLOGIA DEL FRUTO Y LA DOMESTICACION DE MELON/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario de Conservación y Mejora de la Agrodiversidad Valenciana - Institut Universitari de Conservació i Millora de l'Agrodiversitat Valenciana es_ES
dc.description.bibliographicCitation Díaz Bermúdez, A.; Zarouri, B.; Fergany, M.; Eduardo, I.; Álvarez, JA.; Picó Sirvent, MB.; Monforte Gilabert, AJ. (2014). Mapping and Introgression of QTL Involved in Fruit Shape Transgressive Segregation into 'Piel de Sapo' Melon (Cucucumis melo L.). PLoS ONE. 9(8):104188-104188. https://doi.org/10.1371/journal.pone.0104188 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1371/journal.pone.0104188 es_ES
dc.description.upvformatpinicio 104188 es_ES
dc.description.upvformatpfin 104188 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 9 es_ES
dc.description.issue 8 es_ES
dc.relation.senia 276206 es_ES
dc.identifier.pmid 25126852 en_EN
dc.identifier.pmcid PMC4134209 en_EN
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
dc.contributor.funder Instituto Agronómico Mediterráneo de Zaragoza es_ES
dc.contributor.funder Ministerio de Educación es_ES
dc.contributor.funder Consejo Superior de Investigaciones Científicas es_ES
dc.description.references FAO (2014) Food and Agricultural Organization of the United Nations: FAOSTAT http://faostat3.fao.org/faostat-gateway/go/to/download/Q/QC/E es_ES
dc.description.references Ferguson, A. R. (1999). KIWIFRUIT CULTIVARS: BREEDING AND SELECTION. Acta Horticulturae, (498), 43-52. doi:10.17660/actahortic.1999.498.4 es_ES
dc.description.references Butelli, E., Titta, L., Giorgio, M., Mock, H.-P., Matros, A., Peterek, S., … Martin, C. (2008). Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nature Biotechnology, 26(11), 1301-1308. doi:10.1038/nbt.1506 es_ES
dc.description.references Stepansky, A., Kovalski, I., & Perl-Treves, R. (1999). Intraspecific classification of melons (Cucumis melo L.) in view of their phenotypic and molecular variation. Plant Systematics and Evolution, 217(3-4), 313-332. doi:10.1007/bf00984373 es_ES
dc.description.references José, M. A., Iban, E., Silvia, A., & Pere, A. (2005). Inheritance mode of fruit traits in melon: Heterosis for fruit shape and its correlation with genetic distance. Euphytica, 144(1-2), 31-38. doi:10.1007/s10681-005-0201-y es_ES
dc.description.references Pitrat M (2008) Melon. In: Prohens J, Nuez F, editors. Handbook of Plant Breeding, vol Vegetables I: <italic>Asteraceae</italic>, <italic>Brassicaceae</italic>, <italic>Chenopodiaceae</italic>, and <italic>Cucurbitaceae</italic>. Heidelberg: Springer, pp. 283–315. es_ES
dc.description.references Roy, A., Bal, S. S., Fergany, M., Kaur, S., Singh, H., Malik, A. A., … Dhillon, N. P. S. (2011). Wild melon diversity in India (Punjab State). Genetic Resources and Crop Evolution, 59(5), 755-767. doi:10.1007/s10722-011-9716-3 es_ES
dc.description.references Monforte, A. J., Garcia-Mas, J., & Arus, P. (2003). Genetic variability in melon based on microsatellite variation. Plant Breeding, 122(2), 153-157. doi:10.1046/j.1439-0523.2003.00848.x es_ES
dc.description.references Esteras, C., Formisano, G., Roig, C., Díaz, A., Blanca, J., Garcia-Mas, J., … Picó, B. (2013). SNP genotyping in melons: genetic variation, population structure, and linkage disequilibrium. Theoretical and Applied Genetics, 126(5), 1285-1303. doi:10.1007/s00122-013-2053-5 es_ES
dc.description.references Boualem, A., Fergany, M., Fernandez, R., Troadec, C., Martin, A., Morin, H., … Bendahmane, A. (2008). A Conserved Mutation in an Ethylene Biosynthesis Enzyme Leads to Andromonoecy in Melons. Science, 321(5890), 836-838. doi:10.1126/science.1159023 es_ES
dc.description.references C., P., L., H., N., G., D., B., C., D., & M., P. (2002). Genetic control of fruit shape acts prior to anthesis in melon ( Cucumis melo L.). Molecular Genetics and Genomics, 266(6), 933-941. doi:10.1007/s00438-001-0612-y es_ES
dc.description.references Monforte, A. J., Oliver, M., Gonzalo, M. J., Alvarez, J. M., Dolcet-Sanjuan, R., & Arús, P. (2003). Identification of quantitative trait loci involved in fruit quality traits in melon (Cucumis melo L.). Theoretical and Applied Genetics, 108(4), 750-758. doi:10.1007/s00122-003-1483-x es_ES
dc.description.references Eduardo, I., Arús, P., Monforte, A. J., Obando, J., Fernández-Trujillo, J. P., Martínez, J. A., … van der Knaap, E. (2007). Estimating the Genetic Architecture of Fruit Quality Traits in Melon Using a Genomic Library of Near Isogenic Lines. Journal of the American Society for Horticultural Science, 132(1), 80-89. doi:10.21273/jashs.132.1.80 es_ES
dc.description.references Paris, M. K., Zalapa, J. E., McCreight, J. D., & Staub, J. E. (2008). Genetic dissection of fruit quality components in melon (Cucumis melo L.) using a RIL population derived from exotic × elite US Western Shipping germplasm. Molecular Breeding, 22(3), 405-419. doi:10.1007/s11032-008-9185-3 es_ES
dc.description.references Fernández-Silva, I., Moreno, E., Eduardo, I., Arús, P., Álvarez, J. M., & Monforte, A. J. (2008). On the Genetic Control of Heterosis for Fruit Shape in Melon (Cucumis Melo L.). Journal of Heredity, 100(2), 229-235. doi:10.1093/jhered/esn075 es_ES
dc.description.references Fernandez-Silva, I., Moreno, E., Essafi, A., Fergany, M., Garcia-Mas, J., Martín-Hernandez, A. M., … Monforte, A. J. (2010). Shaping melons: agronomic and genetic characterization of QTLs that modify melon fruit morphology. Theoretical and Applied Genetics, 121(5), 931-940. doi:10.1007/s00122-010-1361-2 es_ES
dc.description.references Tomason, Y., Nimmakayala, P., Levi, A., & Reddy, U. K. (2013). Map-based molecular diversity, linkage disequilibrium and association mapping of fruit traits in melon. Molecular Breeding, 31(4), 829-841. doi:10.1007/s11032-013-9837-9 es_ES
dc.description.references Syvänen, A.-C. (2001). Accessing genetic variation: genotyping single nucleotide polymorphisms. Nature Reviews Genetics, 2(12), 930-942. doi:10.1038/35103535 es_ES
dc.description.references Davey, J. W., Hohenlohe, P. A., Etter, P. D., Boone, J. Q., Catchen, J. M., & Blaxter, M. L. (2011). Genome-wide genetic marker discovery and genotyping using next-generation sequencing. Nature Reviews Genetics, 12(7), 499-510. doi:10.1038/nrg3012 es_ES
dc.description.references Fridman, E., Pleban, T., & Zamir, D. (2000). A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484 bp within an invertase gene. Proceedings of the National Academy of Sciences, 97(9), 4718-4723. doi:10.1073/pnas.97.9.4718 es_ES
dc.description.references Frary, A. (2000). fw2.2: A Quantitative Trait Locus Key to the Evolution of Tomato Fruit Size. Science, 289(5476), 85-88. doi:10.1126/science.289.5476.85 es_ES
dc.description.references Liu, J., Van Eck, J., Cong, B., & Tanksley, S. D. (2002). A new class of regulatory genes underlying the cause of pear-shaped tomato fruit. Proceedings of the National Academy of Sciences, 99(20), 13302-13306. doi:10.1073/pnas.162485999 es_ES
dc.description.references Cong, B., Barrero, L. S., & Tanksley, S. D. (2008). Regulatory change in YABBY-like transcription factor led to evolution of extreme fruit size during tomato domestication. Nature Genetics, 40(6), 800-804. doi:10.1038/ng.144 es_ES
dc.description.references Xiao, H., Jiang, N., Schaffner, E., Stockinger, E. J., & van der Knaap, E. (2008). A Retrotransposon-Mediated Gene Duplication Underlies Morphological Variation of Tomato Fruit. Science, 319(5869), 1527-1530. doi:10.1126/science.1153040 es_ES
dc.description.references Li, C. (2006). Rice Domestication by Reducing Shattering. Science, 311(5769), 1936-1939. doi:10.1126/science.1123604 es_ES
dc.description.references Yano, M., Katayose, Y., Ashikari, M., Yamanouchi, U., Monna, L., Fuse, T., … Sasaki, T. (2000). Hd1, a Major Photoperiod Sensitivity Quantitative Trait Locus in Rice, Is Closely Related to the Arabidopsis Flowering Time Gene CONSTANS. The Plant Cell, 12(12), 2473-2483. doi:10.1105/tpc.12.12.2473 es_ES
dc.description.references Takahashi, Y., Shomura, A., Sasaki, T., & Yano, M. (2001). Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the   subunit of protein kinase CK2. Proceedings of the National Academy of Sciences, 98(14), 7922-7927. doi:10.1073/pnas.111136798 es_ES
dc.description.references Kojima, S., Takahashi, Y., Kobayashi, Y., Monna, L., Sasaki, T., Araki, T., & Yano, M. (2002). Hd3a, a Rice Ortholog of the Arabidopsis FT Gene, Promotes Transition to Flowering Downstream of Hd1 under Short-Day Conditions. Plant and Cell Physiology, 43(10), 1096-1105. doi:10.1093/pcp/pcf156 es_ES
dc.description.references Doi, K. (2004). Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1. Genes & Development, 18(8), 926-936. doi:10.1101/gad.1189604 es_ES
dc.description.references Doebley, J., Stec, A., & Hubbard, L. (1997). The evolution of apical dominance in maize. Nature, 386(6624), 485-488. doi:10.1038/386485a0 es_ES
dc.description.references Thornsberry, J. M., Goodman, M. M., Doebley, J., Kresovich, S., Nielsen, D., & Buckler, E. S. (2001). Dwarf8 polymorphisms associate with variation in flowering time. Nature Genetics, 28(3), 286-289. doi:10.1038/90135 es_ES
dc.description.references Salvi, S., Sponza, G., Morgante, M., Tomes, D., Niu, X., Fengler, K. A., … Tuberosa, R. (2007). Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize. Proceedings of the National Academy of Sciences, 104(27), 11376-11381. doi:10.1073/pnas.0704145104 es_ES
dc.description.references Salvi S, Tuberosa R (2007) Cloning QTLs in plants. In: Varshney R, Tuberosa R, editors. Genomics-assisted crop improvement, vol 1. Netherlands: Springer, pp. 207–225. es_ES
dc.description.references Alonso-Blanco, C., Aarts, M. G. M., Bentsink, L., Keurentjes, J. J. B., Reymond, M., Vreugdenhil, D., & Koornneef, M. (2009). What Has Natural Variation Taught Us about Plant Development, Physiology, and Adaptation? The Plant Cell, 21(7), 1877-1896. doi:10.1105/tpc.109.068114 es_ES
dc.description.references Eduardo, I., Arús, P., & Monforte, A. J. (2005). Development of a genomic library of near isogenic lines (NILs) in melon (Cucumis melo L.) from the exotic accession PI161375. Theoretical and Applied Genetics, 112(1), 139-148. doi:10.1007/s00122-005-0116-y es_ES
dc.description.references Vegas, J., Garcia-Mas, J., & Monforte, A. J. (2013). Interaction between QTLs induces an advance in ethylene biosynthesis during melon fruit ripening. Theoretical and Applied Genetics, 126(6), 1531-1544. doi:10.1007/s00122-013-2071-3 es_ES
dc.description.references Essafi, A., Díaz-Pendón, J. A., Moriones, E., Monforte, A. J., Garcia-Mas, J., & Martín-Hernández, A. M. (2008). Dissection of the oligogenic resistance to Cucumber mosaic virus in the melon accession PI 161375. Theoretical and Applied Genetics, 118(2), 275-284. doi:10.1007/s00122-008-0897-x es_ES
dc.description.references Hayden, M. J., Nguyen, T. M., Waterman, A., & Chalmers, K. J. (2008). Multiplex-Ready PCR: A new method for multiplexed SSR and SNP genotyping. BMC Genomics, 9(1), 80. doi:10.1186/1471-2164-9-80 es_ES
dc.description.references Deleu, W., Esteras, C., Roig, C., González-To, M., Fernández-Silva, I., Gonzalez-Ibeas, D., … Garcia-Mas, J. (2009). A set of EST-SNPs for map saturation and cultivar identification in melon. BMC Plant Biology, 9(1), 90. doi:10.1186/1471-2229-9-90 es_ES
dc.description.references Lander, E. S., Green, P., Abrahamson, J., Barlow, A., Daly, M. J., Lincoln, S. E., & Newburg, L. (1987). MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics, 1(2), 174-181. doi:10.1016/0888-7543(87)90010-3 es_ES
dc.description.references KOSAMBI, D. D. (1943). THE ESTIMATION OF MAP DISTANCES FROM RECOMBINATION VALUES. Annals of Eugenics, 12(1), 172-175. doi:10.1111/j.1469-1809.1943.tb02321.x es_ES
dc.description.references Voorrips, R. E. (2002). MapChart: Software for the Graphical Presentation of Linkage Maps and QTLs. Journal of Heredity, 93(1), 77-78. doi:10.1093/jhered/93.1.77 es_ES
dc.description.references Wang S, Basten CJ, Zeng ZB (2007) Windows QTL cartographer 2.5. Department of Statistics, North Carolina State University, Raleigh, NC. es_ES
dc.description.references Zeng, Z. B. (1993). Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci. Proceedings of the National Academy of Sciences, 90(23), 10972-10976. doi:10.1073/pnas.90.23.10972 es_ES
dc.description.references Diaz, A., Fergany, M., Formisano, G., Ziarsolo, P., Blanca, J., Fei, Z., … Monforte, A. J. (2011). A consensus linkage map for molecular markers and Quantitative Trait Loci associated with economically important traits in melon (Cucumis melo L.). BMC Plant Biology, 11(1), 111. doi:10.1186/1471-2229-11-111 es_ES
dc.description.references Noguera, F. J., Capel, J., Alvarez, J. I., & Lozano, R. (2005). Development and mapping of a codominant SCAR marker linked to the andromonoecious gene of melon. Theoretical and Applied Genetics, 110(4), 714-720. doi:10.1007/s00122-004-1897-0 es_ES
dc.description.references Esteras, C., Gomez, P., Monforte, A. J., Blanca, J., Vicente-Dolera, N., Roig, C., … Pico, B. (2012). High-throughput SNP genotyping in Cucurbita pepo for map construction and quantitative trait loci mapping. BMC Genomics, 13(1), 80. doi:10.1186/1471-2164-13-80 es_ES
dc.description.references Kenigsbuch, D., & Cohen, Y. (1990). The inheritance of gynoecy in muskmelon. Genome, 33(3), 317-320. doi:10.1139/g90-049 es_ES
dc.description.references Marguerit, E., Boury, C., Manicki, A., Donnart, M., Butterlin, G., Némorin, A., … Decroocq, S. (2009). Genetic dissection of sex determinism, inflorescence morphology and downy mildew resistance in grapevine. Theoretical and Applied Genetics, 118(7), 1261-1278. doi:10.1007/s00122-009-0979-4 es_ES
dc.description.references Monforte AJ, Díaz A, Caño-Delgado A, van der Knaap E (2014) The genetic basis of fruit morphology in horticultural crops: lessons from tomato and melon. J Exp Bot (online). es_ES
dc.description.references Harel-Beja, R., Tzuri, G., Portnoy, V., Lotan-Pompan, M., Lev, S., Cohen, S., … Katzir, N. (2010). A genetic map of melon highly enriched with fruit quality QTLs and EST markers, including sugar and carotenoid metabolism genes. Theoretical and Applied Genetics, 121(3), 511-533. doi:10.1007/s00122-010-1327-4 es_ES
dc.description.references Chen, K.-Y., & Tanksley, S. D. (2004). High-Resolution Mapping and Functional Analysis of se2.1. Genetics, 168(3), 1563-1573. doi:10.1534/genetics.103.022558 es_ES
dc.description.references Khavkin, E., & Coe, E. H. (1997). Mapped genomic locations for developmental functions and QTLs reflect concerted groups in maize (Zea mays L.). Theoretical and Applied Genetics, 95(3), 343-352. doi:10.1007/s001220050569 es_ES
dc.description.references TUBEROSA, R. (2002). Mapping QTLs Regulating Morpho-physiological Traits and Yield: Case Studies, Shortcomings and Perspectives in Drought-stressed Maize. Annals of Botany, 89(7), 941-963. doi:10.1093/aob/mcf134 es_ES
dc.description.references Yuan, X. J., Pan, J. S., Cai, R., Guan, Y., Liu, L. Z., Zhang, W. W., … Zhu, L. H. (2008). Genetic mapping and QTL analysis of fruit and flower related traits in cucumber (Cucumis sativus L.) using recombinant inbred lines. Euphytica, 164(2), 473-491. doi:10.1007/s10681-008-9722-5 es_ES
dc.description.references Li, D., Cuevas, H. E., Yang, L., Li, Y., Garcia-Mas, J., Zalapa, J., … Weng, Y. (2011). Syntenic relationships between cucumber (Cucumis sativus L.) and melon (C. melo L.) chromosomes as revealed by comparative genetic mapping. BMC Genomics, 12(1). doi:10.1186/1471-2164-12-396 es_ES
dc.description.references Garcia-Mas, J., Benjak, A., Sanseverino, W., Bourgeois, M., Mir, G., Gonzalez, V. M., … Puigdomenech, P. (2012). The genome of melon (Cucumis melo L.). Proceedings of the National Academy of Sciences, 109(29), 11872-11877. doi:10.1073/pnas.1205415109 es_ES
dc.description.references Fazio, G., Staub, J. E., & Stevens, M. R. (2003). Genetic mapping and QTL analysis of horticultural traits in cucumber (Cucumis sativus L.) using recombinant inbred lines. Theoretical and Applied Genetics, 107(5), 864-874. doi:10.1007/s00122-003-1277-1 es_ES
dc.description.references Van der Knaap, E., & Tanksley, S. D. (2003). The making of a bell pepper-shaped tomato fruit: identification of loci controlling fruit morphology in Yellow Stuffer tomato. Theoretical and Applied Genetics, 107(1), 139-147. doi:10.1007/s00122-003-1224-1 es_ES
dc.description.references E., F., Y., L., L., C.-G., A., G., M., S., T., P., … D., Z. (2002). Two tightly linked QTLs modify tomato sugar content via different physiological pathways. Molecular Genetics and Genomics, 266(5), 821-826. doi:10.1007/s00438-001-0599-4 es_ES
dc.description.references Van der Knaap, E., Lippman, Z. B., & Tanksley, S. D. (2002). Extremely elongated tomato fruit controlled by four quantitative trait loci with epistatic interactions. Theoretical and Applied Genetics, 104(2), 241-247. doi:10.1007/s00122-001-0776-1 es_ES


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