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Enantioselective LaIII-pyBOX-Catalyzed Nitro-Michael Addition to (E)-2-Azachalcones

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Enantioselective LaIII-pyBOX-Catalyzed Nitro-Michael Addition to (E)-2-Azachalcones

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dc.contributor.author Blay Llinares, Gonzalo es_ES
dc.contributor.author Incerti, Celia es_ES
dc.contributor.author Muñoz Roca, María del Carmen es_ES
dc.contributor.author Pedro Llinares, Jose Ramón es_ES
dc.date.accessioned 2016-02-08T12:10:40Z
dc.date.issued 2013-03
dc.identifier.issn 1434-193X
dc.identifier.uri http://hdl.handle.net/10251/60692
dc.description.abstract A [La(OTf)3] complex with a new pyBOX ligand bearing a bulky 1-naphthylmethyl substituent at the 4-position of the oxazoline ring catalyzes the conjugate addition of nitroalkanes to a broad range of (E)-2-azachalcones, providing the expected nitro-Michael products with good yields and enanItiomeric excesses up to 87%. The optical purity of the products can be increased by a single crystallization. A plausible stereochemical model to account for the observed stereochemistry has been proposed. es_ES
dc.description.sponsorship Financial support from the Ministerio de Ciencia e Innovacion (MICINN) and Fundo Europeu de Desenvolvimento Regional (FEDER) (grant number CTQ2009-13083) and from Generalitat Valenciana (grant numbers ACOMP/2012/212 and ISIC 2012/001) is acknowledged. en_EN
dc.language Inglés es_ES
dc.publisher Wiley-VCH Verlag es_ES
dc.relation.ispartof European Journal of Organic Chemistry es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Asymmetric catalysis es_ES
dc.subject C–C coupling es_ES
dc.subject Michael addition es_ES
dc.subject Lanthanum es_ES
dc.subject Enones es_ES
dc.subject.classification FISICA APLICADA es_ES
dc.title Enantioselective LaIII-pyBOX-Catalyzed Nitro-Michael Addition to (E)-2-Azachalcones es_ES
dc.type Artículo es_ES
dc.embargo.lift 10000-01-01
dc.embargo.terms forever es_ES
dc.identifier.doi 10.1002/ejoc.201201579
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//CTQ2009-13083/ES/Desarrollo de nuevos procesos enantioselectivos de formación de enlaces C-C mediante catálisis asimétrica/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//ACOMP%2F2012%2F212/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//ISIC%2F2012%2F001/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada es_ES
dc.description.bibliographicCitation Blay Llinares, G.; Incerti, C.; Muñoz Roca, MDC.; Pedro Llinares, JR. (2013). Enantioselective LaIII-pyBOX-Catalyzed Nitro-Michael Addition to (E)-2-Azachalcones. European Journal of Organic Chemistry. 1696-1705. https://doi.org/10.1002/ejoc.201201579 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1002/ejoc.201201579. es_ES
dc.description.upvformatpinicio 1696 es_ES
dc.description.upvformatpfin 1705 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.relation.senia 246054 es_ES
dc.identifier.eissn 099-0690
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
dc.contributor.funder Generalitat Valenciana es_ES
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