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Photosensitization by Imatinib. A Photochemical and Photobiological Study of the Drug and Its Substructures

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Photosensitization by Imatinib. A Photochemical and Photobiological Study of the Drug and Its Substructures

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Nardi, G.; Lhiaubet, VL.; Miranda Alonso, MÁ. (2014). Photosensitization by Imatinib. A Photochemical and Photobiological Study of the Drug and Its Substructures. Chemical Research in Toxicology. 27(11):1990-1995. doi:10.1021/tx500328q

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/60925

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Title: Photosensitization by Imatinib. A Photochemical and Photobiological Study of the Drug and Its Substructures
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Imatinib (IMT) is a promising tyrosine kinase inhibitor used in the treatment of some types of human cancer. It constitutes a successful example of rational drug design based on the optimization of the chemical structure ...[+]
Subjects: Adverse cutaneous reactions , ABC transporter ABCG2 , In-vitro , Mesylate , Flurbiprofen , Inhibition , Therapies , Efficacy , Cancer , Skin
Copyrigths: Cerrado
Source:
Chemical Research in Toxicology. (issn: 0893-228X ) (eissn: 1520-5010 )
DOI: 10.1021/tx500328q
Publisher:
American Chemical Society
Publisher version: http://dx.doi.org/10.1021/tx500328q
Thanks:
The Spanish Government (CTQ2012-32621, RyC-2007-00476, and PFIS FI09/00312), Severo Ochoa Program SEV-2012-0267, the Carlos III Institute of Health (Grant RIRAAF, RETICS Program RD 12/0013/0009), and Generalitat Valenciana ...[+]
Type: Artículo

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