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Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains

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Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains

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Vayá Pérez, I.; Bonancía Roca, P.; Jiménez Molero, MC.; Markovitsi, D.; Gustavsson, T.; Miranda Alonso, MÁ. (2013). Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains. Physical Chemistry Chemical Physics. 15(13):4727-4734. doi:10.1039/c3cp43847c.

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Título: Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains
Autor:
Entidad UPV: Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Fecha difusión:
Resumen:
We report here on the interaction dynamics between flurbiprofen (FBP) and tryptophan (Trp) covalently linked in model dyads and in a complex of FBP with human serum albumin (HSA) probed by time-resolved fluorescence ...[+]
Palabras clave: HUMAN SERUM-ALBUMIN , NONSTEROIDAL ANTIINFLAMMATORY DRUGS , BIOLOGICAL NANOCAVITIES , SPECTROSCOPIC ANALYSIS , OCHRATOXIN-A , BINDING , DYNAMICS , SOLVATION , RESONANCE , PHOSPHORESCENCE
Derechos de uso: Reserva de todos los derechos
Fuente:
Physical Chemistry Chemical Physics. (issn: 1463-9076 ) (eissn: 1463-9084 )
DOI: 10.1039/c3cp43847c
Editorial:
Royal Society of Chemistry
Versión del editor: http://dx.doi.org/10.1039/c3cp43847c
Patrocinador:
Spanish Government CTQ2010-14882 CTQ2009-13699 JCI-2011-09926 BES-2008-003314 PR2011-0581
Generalitat Valenciana 2008/090
Universitat Politecnica de Valencia PAID 05-11 2766
Tipo: Artículo

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