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Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells

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Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells

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Ultimo, A.; Giménez Morales, C.; Bartovsky, P.; Aznar, E.; Sancenón Galarza, F.; Marcos Martínez, MD.; Amoros Del Toro, PJ.... (2016). Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells. Chemistry - A European Journal. 22(5):1582-1586. https://doi.org/10.1002/chem.201504629

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Title: Targeting Innate Immunity with dsRNA-Conjugated Mesoporous Silica Nanoparticles Promotes Antitumor Effects on Breast Cancer Cells
Author: Ultimo, Amelia Giménez Morales, Cristina BARTOVSKY, PAVEL Aznar, Elena Sancenón Galarza, Félix Marcos Martínez, María Dolores Amoros del Toro, Pedro Jose Bernardo, Ana R. Martínez-Máñez, Ramón Jiménez Lara, Ana M. Murguía, Jose R.
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic
Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Issued date:
Abstract:
The authors describe herein a Toll-like receptor 3 (TLR3) targeting delivery system based on mesoporous silica nanoparticles capped with the synthetic double stranded RNA polyinosinic-polycytidylic acid (poly(I:C)) for ...[+]
Subjects: Antitumor agents , Breast carcinoma , Drug delivery , Mesoporous gated materials , Polyinosinic polycytidylic acid
Copyrigths: Reserva de todos los derechos
Source:
Chemistry - A European Journal. (issn: 0947-6539 ) (eissn: 1521-3765 )
DOI: 10.1002/chem.201504629
Publisher:
Wiley
Publisher version: http://dx.doi.org/10.1002/chem.201504629
Project ID:
info:eu-repo/grantAgreement/MICINN//SAF2010-21195/ES/CHIP-SEQ PARA IDENTIFICAR LA RED TRANSCRIPCIONAL DIANA DE LOS RECEPTORES DE ACIDO RETINOICO EN CELULAS DE CANCER DE MAMA/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F047/ES/Nuevas aproximaciones para el diseño de materiales de liberación controlada y la detección de compuestos peligrosos/
info:eu-repo/grantAgreement/MINECO//MAT2012-38429-C04-01/ES/DESARROLLO DE MATERIALES FUNCIONALIZADOS CON PUERTAS NANOSCOPICAS PARA APLICACIONES DE LIBERACION CONTROLADA Y SENSORES PARA LA DETECCION DE NITRATO AMONICO, SULFIDRICO Y CO /
Thanks:
We thank the Spanish Government (projects SAF2010-21195 and MAT2012-38429-C04-01) and the Generalitat Valenciana (project PROMETEOII/2014/047) for support. A.U. and C.G. are grateful to the Ministry of Education, Culture ...[+]
Type: Artículo

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