- -

In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome

Show full item record

Romero Pérez, L.; Trenor Gomis, BA.; Yang, P.; Saiz Rodríguez, FJ.; Clancy, CE. (2014). In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome. Journal of Molecular and Cellular Cardiology. 72:126-137. doi:10.1016/j.yjmcc.2014.02.018

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/63433

Files in this item

Item Metadata

Title: In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome
Author:
UPV Unit: Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Universitat Politècnica de València. Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano - Institut Interuniversitari d'Investigació en Bioenginyeria i Tecnologia Orientada a l'Ésser Humà
Issued date:
Abstract:
Accurate diagnosis of predisposition to long QT syndrome is crucial for reducing the risk of cardiac arrhythmias. In recent years, drug-induced provocative tests have proved useful to unmask some latent mutations linked ...[+]
Subjects: Mutations , Drug-induced long-QT syndrome , Drug-induced arrhythmias , Computer modeling , Potassium channels , Genetics
Copyrigths: Reserva de todos los derechos
Source:
Journal of Molecular and Cellular Cardiology. (issn: 0022-2828 ) (eissn: 1095-8584 )
DOI: 10.1016/j.yjmcc.2014.02.018
Publisher:
Elsevier
Publisher version: http://dx.doi.org/10.1016/j.yjmcc.2014.02.018
Thanks:
This work was partially supported by the "VI Plan Nacional de Investigacion Cientifica, Desarrollo e Innovacion Tecnologica" from the Ministerio de Economia y Competitividad of Spain (TIN2012-37546-CO3-01) and the European ...[+]
Type: Artículo

This item appears in the following Collection(s)

Show full item record