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Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering

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Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering

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dc.contributor.author Demirdogen, Bermali es_ES
dc.contributor.author Plazas Bonilla, Clara Eugenia es_ES
dc.contributor.author Trujillo, Sara es_ES
dc.contributor.author Perilla, J.E. es_ES
dc.contributor.author Elcin, A.E. es_ES
dc.contributor.author Elcin, Yasar Murat es_ES
dc.contributor.author Gómez Ribelles, José Luís es_ES
dc.date.accessioned 2016-05-17T07:27:03Z
dc.date.available 2016-05-17T07:27:03Z
dc.date.issued 2014-09
dc.identifier.issn 1549-3296
dc.identifier.uri http://hdl.handle.net/10251/64182
dc.description.abstract Polycaprolactone/silica microporous hybrid membranes were produced in two steps: A microporous polycaprolactone membrane with an interconnected porosity of 80% was obtained via a freeze extraction procedure, then silica was formed by a sol-gel reaction inside the micropores using tetraethyl orthosilicate, TEOS, as silica precursor. It is shown that silica forms a thin coating layer homogeneously distributed over the pore walls when sol-gel reaction is catalyzed by hydrochloric acid, while it forms submicron spherical particles when using basic catalyzer. Some physical properties and the viability and osteoblastic differentiation of bone marrow rat mesenchymal stem cells cultured on pure and hybrid membranes were studied. es_ES
dc.description.sponsorship Contract grant sponsors: COOPEN Project. Turkish Academy of Sciences, TUBA; VI National R&D&I Plan 2008-2011; Iniciativa Ingenio 2010; Consolider Program; CIBER Actions; Instituto de Salud Carlos III; European Regional Development Fund en_EN
dc.language Inglés es_ES
dc.publisher Wiley es_ES
dc.relation.ispartof Journal of Biomedical Materials Research Part A es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject polycaprolactone-silica es_ES
dc.subject hybrid composites es_ES
dc.subject mesenchymal stem cells es_ES
dc.subject osteogenic differentiation es_ES
dc.subject silica coating es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1002/jbm.a.34999
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2010-21611-C03-01/ES/MATERIALES BIOESTABLES Y BIOREABSORBIBLES A LARGO PLAZO COMO SOPORTES MACROPOROSOS PARA LA REGENERACION DEL CARTILAGO ARTICULAR/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular es_ES
dc.description.bibliographicCitation Demirdogen, B.; Plazas Bonilla, CE.; Trujillo, S.; Perilla, J.; Elcin, A.; Elcin, YM.; Gómez Ribelles, JL. (2014). Silica coating of the pore walls of a microporous polycaprolactone membrane to be used in bone tissue engineering. Journal of Biomedical Materials Research Part A. 102(9):3229-3236. https://doi.org/10.1002/jbm.a.34999 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1002/jbm.a.34999 es_ES
dc.description.upvformatpinicio 3229 es_ES
dc.description.upvformatpfin 3236 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 102 es_ES
dc.description.issue 9 es_ES
dc.relation.senia 284983 es_ES
dc.identifier.eissn 1552-4965
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
dc.contributor.funder European Commission es_ES
dc.contributor.funder Turkish Academy of Sciences es_ES
dc.contributor.funder Instituto de Salud Carlos III es_ES
dc.contributor.funder European Regional Development Fund es_ES


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