Pandis, C.; Madeira, S.; Matos, J.; Kyritsis, A.; Mano, J.; Gómez Ribelles, JL. (2014). Chitosan-silica hybrid porous membranes. Materials Science and Engineering: C. 42:553-561. https://doi.org/10.1016/j.msec.2014.05.073
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/64202
Title:
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Chitosan-silica hybrid porous membranes
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Author:
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Pandis, Christos
Madeira, Sara
Matos, Joana
Kyritsis, Apostolos
Mano, Joao
Gómez Ribelles, José Luís
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UPV Unit:
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Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada
Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular
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Issued date:
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Abstract:
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Chitosan-silica porous hybrids were prepared by a novel strategy in order to improve the mechanical properties of chitosan (CHT) in the hydrogel state. The inorganic silica phase was introduced by sal-gel reactions in ...[+]
Chitosan-silica porous hybrids were prepared by a novel strategy in order to improve the mechanical properties of chitosan (CHT) in the hydrogel state. The inorganic silica phase was introduced by sal-gel reactions in acidic medium inside the pores of already prepared porous scaffolds. In order to make the scaffolds insoluble in acidic media chitosan was cross-linked by genipin (GEN) with an optimum GEN concentration of 32 wt%. Sol-gel reactions took place with Tetraethylorthosilicate (TEOS) and 3-glycidoxypropyltrimethoxysilane (GPTMS) acting as silica precursors. GPTMS served also as a coupling agent between the free amino groups of chitosan and the silica network The morphology study of the composite revealed that the silica phase appears as a layer covering the chitosan membrane pore walls. The mechanical properties of the hybrids were characterized by means of compressive stress-strain measurements. By immersion in water the hybrids exhibit an increase in elastic modulus up to two orders of magnitude.
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Subjects:
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Chitosan
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Silica
,
Genipin
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Scaffolds
,
Hybrid
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Mechanical properties
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Copyrigths:
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Cerrado |
Source:
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Materials Science and Engineering: C. (issn:
0928-4931
) (eissn:
1873-0191
)
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DOI:
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10.1016/j.msec.2014.05.073
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Publisher:
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Elsevier
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Publisher version:
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http://dx.doi.org/10.1016/j.msec.2014.05.073
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Project ID:
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info:eu-repo/grantAgreement/GSRT//NARGEL-PE5 (2551)/
info:eu-repo/grantAgreement/FCT/5876-PPCDTI/115048/PT/SupraRelax: Molecular mobility of biodegradable polymer in ultra-confined supramolecular organized geometries/
info:eu-repo/grantAgreement/MINECO//MAT2013-46467-C4-1-R/ES/ESTIMULACION MECANICA LOCAL DE CELULAS MESENQUIMALES DE CARA A SU DIFERENCIACION OSTEOGENICA Y CONDROGENICA EN MEDICINA REGENERATIVA/
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Thanks:
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The research project is implemented within the framework of the Action "Supporting Postdoctoral Researchers" of the Operational Program "Education and Lifelong Learning" (Action's Beneficiary: General Secretariat for ...[+]
The research project is implemented within the framework of the Action "Supporting Postdoctoral Researchers" of the Operational Program "Education and Lifelong Learning" (Action's Beneficiary: General Secretariat for Research and Technology), and is co-financed by the European Social Fund (ESF) and the Greek State, Grant Number: NARGEL-PE5(2551). JFM thanks the Portuguese Foundation for Science and Technology (FCT) for financial support through the PTDC/FIS/115048/2009 project. JLGR acknowledges the support of the Ministerio de Economia y Competitividad, MINECO, through the MAT2013-46467-C4-1-R project.
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Type:
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Artículo
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