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Physical-chemical properties of cross-linked chitosan electrospun fiber mats

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Physical-chemical properties of cross-linked chitosan electrospun fiber mats

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dc.contributor.author Sencadas, Vitor Joao Gomes Da Silva es_ES
dc.contributor.author Correia, Daniela es_ES
dc.contributor.author Ribeiro, Clarisse es_ES
dc.contributor.author Moreira, S. es_ES
dc.contributor.author Botelho, G. es_ES
dc.contributor.author Gómez Ribelles, José Luís es_ES
dc.contributor.author Lanceros Mendez, Senen es_ES
dc.date.accessioned 2016-05-17T09:16:43Z
dc.date.available 2016-05-17T09:16:43Z
dc.date.issued 2012-12
dc.identifier.issn 0142-9418
dc.identifier.uri http://hdl.handle.net/10251/64210
dc.description.abstract Chitosan fiber mats were successfully processed by electrospinning. The as-spun fiber mats were neutralized with ethanol and cross-linked with glutaraldehyde. A decrease of the fiber average diameter from 243 +/- 43 nm down to 215.53 nm was observed for the neutralized and cross-linking chitosan membrane. It was found that the processing conditions do not alter the initial deacetylation degree of the polymer. Polymer crystallinity index showed a decrease from 61% for the Protasan material down to 17% for the cross-linking fiber mats. A swelling index up to 1000% was observed for the cross-linked samples. Preliminary MC-3T3-E1 cell culture results showed good cell adhesion and proliferation in the cross-linked chitosan fiber mats. es_ES
dc.description.sponsorship This work is funded by FEDER funds through the "Programa Operacional Factores de Competitividade - COMPETE" and by national funds by FCT - Fundacao para a Ciencia e a Tecnologia, project references NANO/NMed-SD/0156/2007. V.S. and SM thanks the FCT grants SFRH/BPD/63148/2009 and SFRH/BPD/64726/2009, respectively. The authors also thank the support of the COST Action MP1003, 2010 'European Scientific Network for Artificial Muscles' (ESNAM). JLGR acknowledge the support of the Spanish Ministry of Science and Innovation through project No. MAT2010-21611-C03-01 (including the FEDER financial support) and Programa Nacional de Internacionalizacion de la I+D project EUI2008-00126. The authors also thank the National NMR Network (National Program for Scientific Re-equipment, REDE/1517/RMN/2005, funds from POCI 2010 (FEDER) and FCT) and Microscopy Service of the UPV for the use of their lab. en_EN
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Polymer Testing es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Chitosan scaffolds es_ES
dc.subject Electrospinning es_ES
dc.subject Crystallinity es_ES
dc.subject Biomaterials es_ES
dc.subject Nanofibers es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title Physical-chemical properties of cross-linked chitosan electrospun fiber mats es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.polymertesting.2012.07.010
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2010-21611-C03-01/ES/MATERIALES BIOESTABLES Y BIOREABSORBIBLES A LARGO PLAZO COMO SOPORTES MACROPOROSOS PARA LA REGENERACION DEL CARTILAGO ARTICULAR/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/J4FCT/SFRH/SFRH/BPD/64726/2009/PT/
dc.relation.projectID info:eu-repo/grantAgreement/J4FCT/SFRH/SFRH/BPD/63148/2009/PT/
dc.relation.projectID info:eu-repo/grantAgreement/FCT//MCTES%2FREDE%2F1517%2FRMN%2F2005/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//EUI2008-00126/ES/SMART JOINT IMPLANTS USING BIONANOCOMPOSITES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/J4FCT/5876-PPCDTI/109368/PT/
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Sencadas, VJGDS.; Correia, D.; Ribeiro, C.; Moreira, S.; Botelho, G.; Gómez Ribelles, JL.; Lanceros Mendez, S. (2012). Physical-chemical properties of cross-linked chitosan electrospun fiber mats. Polymer Testing. 31(8):1062-1069. https://doi.org/10.1016/j.polymertesting.2012.07.010 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.polymertesting.2012.07.010 es_ES
dc.description.upvformatpinicio 1062 es_ES
dc.description.upvformatpfin 1069 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 31 es_ES
dc.description.issue 8 es_ES
dc.relation.senia 239471 es_ES
dc.contributor.funder Fundação para a Ciência e a Tecnologia, Portugal es_ES


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